My doctor told me I must have had a number of these small white matter strokes. Of course he never showed my any of my scans so he could have been pulling stuff out of thin air.
http://m.medicalxpress.com/news/2016-12-brain-silent.html
UCLA researchers have shown that the brain can be repaired—and
brain function can be recovered—after a stroke in animals. The discovery
could have important implications for treating a mind-robbing condition
known as a white matter stroke, a major cause of dementia.
White matter stroke is a type of ischemic stroke, in which a blood vessel carrying oxygen to the brain is blocked. Unlike large artery blockages or transient ischemic attacks,
individual white matter strokes, which occur in tiny blood vessels deep
within the brain, typically go unnoticed but accumulate over time. They
accelerate Alzheimer's disease due to damage done to areas of the brain
involved in memory, planning, walking and problem-solving.
"Despite how common and devastating white matter stroke is there has
been little understanding of how the brain responds and if it can
recover," said Dr. Thomas Carmichael, senior author of the study and a
professor of neurology at the David Geffen School of Medicine at UCLA.
"By studying the mechanisms and limitations of brain repair in this type
of stroke, we will be able to identify new therapies to prevent disease
progression and enhance recovery."
In a five-year study, Carmichael's team looked at white matter strokes in animals and found that the brain
initiated repair by sending replacement cells to the site, but then the
process stalled. The team had a short list of molecular suspects from
previous research that they thought might be responsible. Researchers
identified a molecular receptor as the likely culprit in stalling the
repair; when they blocked the receptor, the animals began to recover
from the stroke.
"White matter stroke is an important clinical target for the development of new therapies," Carmichael said.
Annually in the United States, about 795,000 suffer a stroke,
resulting in nearly 130,000 deaths. Multiply the number of strokes by
six, and you'll have an estimate of the number of strokes that are
"silent," in that they do not produce symptoms that lead to
hospitalization. Most of these silent strokes are white matter strokes.
The paper was published in the electronic edition of the Proceedings of the National Academy of Sciences.
More information: Elif G. Sozmen et al. Nogo receptor
blockade overcomes remyelination failure after white matter stroke and
stimulates functional recovery in aged mice, Proceedings of the National Academy of Sciences (2016). DOI: 10.1073/pnas.1615322113
Provided by: University of California, Los Angeles
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,112 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
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Doesn't this research have a lot of potential? Does it ever address for how long the repair efforts last? For example, is my brain continuing to try or has it been blocked for too long? How long is that? So many opportunities for additional research.
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