Effectiveness and safety of music-supported therapy on mood in post-stroke rehabilitation patients

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Effectiveness and safety of music-supported therapy on mood in post-stroke rehabilitation patients

A protocol for systematic review and meta-analysis

Ding, Jie MM^a; Xiao, Yuanyi MM^b; Yuan, Fuqiang MM^b; Luo, Zhaona MM^b; Hu, Jinyu MM^c,∗

Author Information

Medicine: March 26, 2021 - Volume 100 - Issue 12 - p e25077

doi: 10.1097/MD.0000000000025077

• Open

Abstract

Background: 

Music-supported therapy has been widely used clinically to relieve post-stroke rehabilitation. However, the efficacy of Music-supported therapy in the treatment of Mood in post-stroke rehabilitation Patients is uncertain. The purpose of this study is to determine the effectiveness and safety of Music-supported therapy in the treatment of Mood in post-stroke rehabilitation Patients.

Methods: 

Search PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure Database, Wanfang Database, China Science and Technology Journal Database, China Biomedical Literature Database, and search related randomized controlled trials. Two reviewers will independently select studies, collect data, and evaluate methodological quality through the Cochrane Deviation Risk Tool. Revman V.5.3 will be used for meta-analysis.

Results: 

This study will evaluate the current status of Music-supported therapy treatment for mood in post-stroke rehabilitation Patients, aiming to illustrate the effectiveness and safety of Music-supported therapy treatment.

Conclusion: 

This study will provide a basis for judging whether Music-supported therapy is effective in treating mood in post-stroke rehabilitation Patients.

INPLASY registration number: 

INPLASY202120011.

1 Introduction

Stroke is one of the main diseases that seriously damage human health. It has the characteristics of high morbidity, high disability and high mortality.^[1] The main clinical manifestations of post-stroke patients are long-term physical and psychological problems, including movement and function, balance, pain, sensation, perception, cognition, attention, memory, and emotional problems.^[2] Among them, motor dysfunction, anxiety and depression are the most important factors that hinder patients from participating in daily activities after stroke and restrict their occupational rehabilitation.^[3,4] According to epidemiological studies Post-stroke depression is presented in 32.9% to 35.9% of stroke patients, which is significantly higher than the prevalence of depression in the general population (10%).^[5] Rehabilitation after stroke has caused many social problems, including patients’psychological depression and increasing the country's overall medical expenses.^[6]

The etiology of stroke was divided by hemorrhage and infarction, In addition, other evidence suggests it is usually caused by many factors such as the obesity epidemic, diabetes, heart failure, and the overall lack of physical activity among the general population.^[7] At present, major goals of treatment are to reduce depressive symptoms, improve mood and quality of life, and reduce the risk of medical complications as well as the relapse of post-stroke depression.^[8] However, antidepressants are generally not indicated in mild forms because the balance of benefit and risk is not satisfactory in stroke patients.^[9]

Music-supported therapy (MST) is a promising new treatment,^[10] and extensive research suggests that it could be useful because of its promotion of relaxation and both cognitive and motor improvement in stroke rehabilitation.^[11] There are many studies with music therapy on mood in post-stroke patients, although music therapy has been used in rehabilitation to stimulate brain functions involved in emotion, cognition, speech, and sensory perceptions.^[12,13]

The focus of this study is the efficacy of Music-supported therapy on mood in post-stroke rehabilitation Patients. Therefore, we conducted this study to systematically evaluate the impact of Music-supported therapy on post-stroke rehabilitation Patients. It can provide a basis for the diagnosis and treatment of MST for post-stroke rehabilitation Patients.