A translational roadmap for transcranial magnetic and direct current stimulation in stroke rehabilitation: Consensus- based core recommendations from the third stroke recovery and rehabilitation roundtable

Thiis 'expert' panel totally missed the only goal in stroke: 100% RECOVERY! With stroke medical 'professionals' not even trying for the right goals, stroke survivors will be forever screwed!

 A translational roadmap for transcranial magnetic and direct current stimulation
in stroke rehabilitation: Consensus-based core recommendations from the
third stroke recovery and rehabilitation roundtable

https://doi.org/10.1177/17474930231203982
International Journal of Stroke
1 –13
© 2023 World Stroke Organization
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DOI: 10.1177/17474930231203982
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International Journal of Stroke, 00(0)
A translational roadmap for transcranial
magnetic and direct current stimulation
in stroke rehabilitation: Consensus-
based core recommendations from the
third stroke recovery and rehabilitation
roundtable
Jodi D Edwards1,2 , Adan Ulises Dominguez-Vargas3 ,
Charlotte Rosso4
, Meret Branscheidt5
, Lisa Sheehy6
,
Fanny Quandt7 , Simon A Zamora5
, Melanie K Fleming8
,
Valentina Azzollini9
, Ronan A Mooney10
, Charlotte J Stagg8
,
Chiristian Gerloff 7 , Simone Rossi11
, Leonardo G Cohen9
,
Pablo Celnik 10
, Michael A Nitsche12
, Cathrin M Buetefisch13
and Numa Dancause3

Abstract

Background and Aims:  

The purpose of this Third Stroke Recovery and Rehabilitation Roundtable (SRRR3) was
to develop consensus recommendations to address outstanding barriers for the translation of preclinical and clinical research using the non-invasive brain stimulation (NIBS) techniques Transcranial Magnetic Stimulation (TMS) and Transcranial Direct Current Stimulation (tDCS) and provide a roadmap for the integration of these techniques into clinical practice.
Methods: International NIBS and stroke recovery experts (N = 18) contributed to the consensus process. Using a nominal group technique, recommendations were reached via a five-stage process, involving a thematic survey, two priority ranking surveys, a literature review and an in-person meeting.
 

Results and Conclusions:  

Results of our consensus process yielded five key evidence-based and feasibility barriers for
the translation of preclinical and clinical NIBS research, which were formulated into five core consensus recommendations. Recommendations highlight an urgent need for (1) increased understanding of NIBS mechanisms, (2) improved methodological rigor in both preclinical and clinical NIBS studies, (3) standardization of outcome measures, (4) increased clinical relevance in preclinical animal models, and (5) greater optimization and individualization of NIBS protocols.
To facilitate the implementation of these recommendations, the expert panel developed a new SRRR3 Unified NIBS Research Checklist. These recommendations represent a translational pathway for the use of NIBS in stroke rehabilitation research and practice.
1University of Ottawa Heart Institute, Ottawa, ON, Canada
2School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada
3Université de Montréal, Montréal, QC, Canada
4Institut du Cerveau et de la Moelle épinière, Paris, France
5Cereneo Center for Neurology and Rehabilitation, Vitznau, Switzerland
6Bruyére Research Institute, Ottawa, ON, Canada
7University Medical Center Hamburg-Eppendorf, Hamburg, Germany
8University of Oxford, Oxford, UK
9National Institutes of Health, Bethesda, MD, USA
10 Johns Hopkins University, Baltimore, MD, USA
11 University of Siena, Siena, Italy
12 Leibniz Research Center for Working Environment and Human Factors, Dortmund, Germany
13 Emory University, Atlanta, GA, USA
This contribution, first published in International Journal of Stroke, is being co-published in the following journals: Neurorehabilitation and Neural Repair.