When I had a fitbit it assumed any 10 foot gain in elevation was a flight of stairs. Is this talking about real stairs or fitbit stairs?
Daily stair climbing, disease susceptibility, and risk of atherosclerotic cardiovascular disease: A prospective cohort study
Published:September 15, 2023DOI:https://doi.org/10.1016/j.atherosclerosis.2023.117300
Highlights
- •This large cohort of UK adults demonstrated that climbing more than five flights of stairs daily was associated with over a 20% lower risk of ASCVD.
- •The associations were broadly concordant in populations with varying susceptibilities to ASCVD.
- •Participants who discontinued stair climbing between the baseline and resurvey exhibited a higher risk of ASCVD in comparison to those who never engaged in stair climbing.
Abstract
Background and aims
The associations between intensity of stair climbing and atherosclerotic cardiovascular
disease (ASCVD) and how these vary by underlying disease susceptibility are not fully
understood. We aim to evaluate the intensity of stair climbing and risk of ASCVD types
and whether these vary with the presence of ASCVD risk factors.
Methods
This prospective study used data of 458,860 adult participants from the UK Biobank.
Information about stair climbing, sociodemographic, and lifestyle factors was collected
at baseline and a resurvey 5 years after baseline. ASCVD was defined as coronary artery
disease (CAD), ischemic stroke (IS), or acute complications. Associations between
flights of stair climbing and ASCVD were examined as hazard ratios (HRs) from Cox
proportional hazards models. The modification role of disease susceptibility on such
associations was assessed by analyses stratified by levels of genetic risk score (GRS),
10-year risks of ASCVD, and self-reported family history of ASCVD.
Results
During a median of 12.5 years of follow-up, 39,043 ASCVD, 30,718 CAD, and 10,521 IS
cases were recorded. Compared with the reference group (reported climbing stairs 0
times/day at baseline), the multivariable-adjusted HRs for ASCVD were 0.97 (95% CI,
0.93–1.01), 0.84 (0.82–0.87), 0.78 (0.75–0.81), 0.77 (0.73–0.80) and 0.81 (0.77–0.85)
for stair climbing of 1–5, 6–10, 11–15, 16–20 and ≥21 times/day, respectively. Comparable
results were obtained for CAD and IS. When stratified by different disease susceptibility
based on the GRS for CAD/IS, 10-year risk, and family history of ASCVD, the protection
association of stair climbing was attenuated by increasing levels of disease susceptibility.
Furthermore, compared with people who reported no stair climbing (<5 times/d) at two
examinations, those who climbed stairs at baseline and then stopped at resurvey experienced
a 32% higher risk of ASCVD (HR 1.32, 95% CI:1.06–1.65).
Conclusions
Climbing more than five flights of stairs (approx 50 steps) daily was associated with
a lower risk of ASCVD types independent of disease susceptibility. Participants who
stopped stair climbing between baseline and resurvey had a higher risk of ASCVD compared
with those who never climbed stairs.
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