Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, June 3, 2021

Functional plasticity induced by mirror training: the mirror as the element connecting both hands to one hemisphere

 At least they seem to have a protocol although I'd have to get a much larger mirror. I guess orthogonal( intersecting or lying at right angles), is between your legs. So I wonder, is this better than the iPsiHand?    WHOM will be doing the research to determine the best method for recovering the hand?

FDA-Approved Device Will Help Stroke Victims Regain Use Of Hands

The latest here:

Functional plasticity induced by mirror training: the mirror as the element connecting both hands to one hemisphere

First Published January 13, 2012 Research Article Find in PubMed 

Background

Mirror therapy (MT) is a promising therapeutic approach in stroke patients with severe hand paresis.  

Objective

The ipsilateral (contralesional) primary sensorimotor cortex (SMC) and the mirror neuron system have been suggested to play decisive roles in the MT network. The present study investigated its underlying neural plasticity.  

Methods

Two groups of healthy participants (n = 13 in each group) performed standardized fine motor tasks moving pegs and marbles (20 min/d for 4 days) with their right hand with either a mirror (mirror training group, MG) or a nonreflective board (control training group, CG) positioned orthogonally in front of them. The number of items moved by each hand was tested after each training session. Functional MRI (fMRI) was acquired before and after the training procedure to investigate the mirror training (MTr)-specific network by the analysis of the factors Time and Group.  

Results

The hand performance test of the trained right hand did not differ between the 2 groups. The untrained left hand improved significantly more in the MG compared with the CG. fMRI analysis of action observation and imitation of grasping tasks demonstrated MTr-specific activation changes within the right dorsal and left ventral premotor cortex as well as in the left SMC (SMCleft). Analysis of functional and effective connectivity showed a MTr-specific increase of functional coupling between each premotor region and the left supplementary motor area, which in turn showed an increased functional interaction with the ipsilateral SMCleft.  

Conclusions

MTr remodels the motor system by functionally connecting hand movement to the ipsilateral SMC. On a system level, it leads to interference of the neural circuit related to motor programming and observation of the trained hand with the illusionary movement of the untrained hand.

Effective stroke management is important as the treatment of stroke consumes a significant amount of resources.1 Functional recovery can occur even in the chronic stage of stroke with plastic changes induced in the affected primary motor cortex (M1) by intense motor training of the paretic hand.2,3 Additional commitment of noninvasive stimulation over the affected M1 by repetitive transcranial magnetic stimulation (TMS)4 or by transcranial direct current stimulation5 promotes functional recovery in association with plastic changes within the affected M1. However, the effectiveness of such strategies is limited to patients with mild to moderate hand paresis. Thus, an effective therapy regime for patients with severe hand paresis or loss of hand function is still lacking.

Mirror therapy (MT) is a promising therapeutic approach in stroke patients, even in those with complete loss of hand function. By using a mirror that is positioned orthogonally in front of the patient, the reflection of the right arm in the mirror provides an illusion that the left arm is being moved. MT was first described by Ramachandran and colleagues6 in patients with phantom pain after limb amputation and has been suggested to improve hand functional deficit in stroke patients.7 Ramachandran and Altschuler8 suggested that the ipsilateral (contralesional) corticospinal tracts from the M1 play a role while training with a mirror,8 but a recent functional MRI (fMRI) study reported an activation shift toward the ipsilesional sensorimotor cortex (SMC) after MT in chronic stroke patients in contrast with a control group.9 It has also been suggested that the mirror neuron system (MNS) plays an important role while observing one’s hand in the mirror and training via action observation (AO) and imitation (IMI).8,10

The underlying neural plasticity of MT is currently unknown. Therefore, in the present study, fMRI was used to address this issue. We focused on training-induced plasticity by training with a mirror rather than the direct effect of observing one’s hand in the mirror, as was investigated with the use of functional imaging11,12 or TMS.13-15

 
 

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