Deans' stroke musings: The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, June 11, 2021

The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion

No clue what use this is for recovery. If you can do complex finger movements you are extremely high functioning.

The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion

The Journal of Neuroscience, May 31, 2006
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26(22):6096–6102
MartinLotze, 1,2
JochenMarkert, 1
PaulSauseng, 3
JuliaHoppe, 1,4
ChristianPlewnia, 5
andChristianGerloff 1,4

1 Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, D-72076 Tuebingen, Germany,
2 Institute of Medical Psychology and Behavioral Neurobiology, University of Tuebingen, D-72074 Tuebingen, Germany,
3 Department of Psychology, University of Salzburg, A-5020 Salzburg, Austria,
4 Department of Neurology, University Medical Center Hamburg–Eppendorf, D-20246 Hamburg, Germany, and
5 Department of Psychiatry and Psychotherapy, University of Tuebingen, D-72072 Tuebingen, Germany

Abstract

Imaging techniques document enhanced activity in multiple motor areas of the damaged and contralesional (intact) hemisphere (CON-H) after stroke. In the subacute stage, increased activity within motor areas in the CON-H during simple movements of the affected hand has been shown to correlate with poorer motor outcome. For those patients in the chronic stage who recovered well, the functional relevance of an increased activation within the CON-H is unclear. Using trains of repetitive transcranial magnetic stimulation (TMS) during performance of complex finger movements, we tested the behavioral relevance of regional functional magnetic resonance imaging (fMRI) activation within the CON-H for sequential finger movement performance of the recovered hand in seven patients who had experienced a subcortical stroke. TMS was navigated over fMRI activation maxima within anatomically preselected regions of the CON-H, and effects were compared with those of healthy controls. Stimulation over the dorsal premotor cortex (dPMC), the primary motor cortex (M1), and the superior parietal lobe (SPL) resulted in significant interference with recovered performance in patients. Interference with the dPMC and M1 induced timing errors only, SPL stimulation caused both timing and accuracy deficits. The present results argue for a persistent beneficial role of the dPMC, M1, and SPL of the CON-H on some aspects of effectively recovered complex motor behavior after subcortical stroke.