Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, October 27, 2022

Best Evidence Yet That Lowering Blood Pressure Can Prevent Dementia

But we don't know how low is good enough, there is no protocol here so your doctor will be just guessing as what to do. Hope they guess right. 

Best Evidence Yet That Lowering Blood Pressure Can Prevent Dementia

A global study of over 28,000 people, published in the European Heart Journal, has provided the strongest evidence to date that lowering blood pressure in later life can cut the risk of dementia.

Ruth Peters, University of New South Wales, Sydney, Australia, said that in the absence of significant dementia treatment breakthroughs, reducing the risk of developing the disease would be a welcome step forward.

“Given population ageing and the substantial costs of caring for people with dementia, even a small reduction could have considerable global impact,” she said. “Our study suggests that using readily available treatments to lower blood pressure is currently one of our ‘best bets’ to tackle this insidious disease.”

Dr. Peters explained that while many trials have looked at the health benefits of lowering blood pressure, not many included dementia outcomes and even fewer were placebo-controlled.

“Most trials were stopped early because of the significant impact of blood pressure lowering on cardiovascular events, which tend to occur earlier than signs of dementia,” she said.

To examine the relationship between blood pressure and dementia more closely, the researchers analysed 5 double-blind placebo-controlled randomised trials that used different blood pressure-lowering treatments and followed patients until the development of dementia. A total of 28,008 individuals with an average age of 69 years and a history of high blood pressure from 20 countries were included. Across these studies, the mid-range of follow up was just over 4 years.

“We found there was a significant effect of treatment in lowering the odds of dementia associated with a sustained reduction in blood pressure in this older population,” said Dr Peters. “Our results imply a broadly linear relationship between blood pressure reduction and lower risk of dementia, regardless of which type of treatment was used.”

The researchers hope the results will help in designing public health measures to slow the advance of dementia as well as informing treatment, where there may be hesitations around how far to lower blood pressure in older age.

“Our study provides the highest grade of available evidence to show that blood pressure lowering treatment over several years reduces the risk of dementia, and we did not see any evidence of harm,” said Dr Peters. “But what we still don’t know is whether additional blood pressure-lowering in people who already have it well-controlled or starting treatment earlier in life would reduce the long-term risk of dementia.”

Reference: https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehac584/6770632

SOURCE: George Institute for Global Health

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