Deans' stroke musings: Optimised ladder‐climbing rehabilitation training for various stroke severity levels in rats

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, October 22, 2022

Optimised ladder‐climbing rehabilitation training for various stroke severity levels in rats

This should easily translate to human testing using stair climbers, even your doctor could set up research on that.

Optimised ladder‐climbing rehabilitation training for various stroke severity levels in rats

Chi‐ChunChen1|Yu‐LinWang2,3,4|Ching‐PingChang5

1. Department of Electronic Engineering, National ChinYi University of Technology, Taichung, Taiwan

2. Center of General Education, Southern Taiwan University of Science and Technology, Tainan, Taiwan 3. College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

4. Department of Rehabilitation, Chi Mei Medical Center,Tainan,Taiwan

5. Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan

Abstract

To develop an optimised rehabilitation training system for various severity strokes in rats.The method provided feedback regarding the rat's measured position to a microprocessor, which adjusted the training speed accordingly and enables the rat to continuously exercise in the middle position of the ladder. This created a cyclic control system that provided various training intensities based on timely evaluations of the ladder climbing capabilities of each rat, thus providing a suitable rehabilitation method for subjects with various stroke severities. The modified neurological severity score, rotarod and cerebral infarction volume results for the 60‐and 90‐min middle cerebral artery occlusion(MCAO) treadmill groups did not differ significantly from those of the control group.Conversely, the cerebral infarction volumes of the ladder climbing rehabilitation groups in the 30‐, 60‐, and 90‐min MCAO were all significantly lower than those of the control group(84.03�23.24vs. 256.77�85.63(mm3), 265.19�41.12versus377.17�90.97(mm3), and 303.80�47.15versus452.68�90.44(mm3) respectively), therebyindicatingthe optimisedladder‐climbingmethodas effective for subjectswithvariousstrokese-verities. Individualdifferencesmay causedifferentexercise capacitiesfor each participant.To accommodatefor theseexercise capacities, an optimisedladder‐climbingrehabilitationtrainingsystemwas proposed,whichprovided trainingaccordingto the physical abilitiesof eachparticipant.