Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, October 21, 2022

New genetic engineering company aims to develop neuroactive compounds from plants, fungi

With all this research already out there and the US setting up additional research maybe we'll finally get somewhere in using these to treat stroke.

U.S. gets its first psychedelics research center September 2019

 

The latest here:

New genetic engineering company aims to develop neuroactive compounds from plants, fungi 

Empyrean Neuroscience Inc. has announced its launch as a genetic engineering company dedicated to developing fungi- and plant-based therapeutics for the treatment of neuropsychiatric and neurologic disorders.

According to a company release, Empyrean was backed by $22 million Series A funding and founded on a platform designed to identify therapeutic fungal alkaloids, cannabinoids and other small molecules with enhanced efficacy and safety. The platform will also be used for the discovery of new small molecules with potential therapeutic benefits.

Psychotropic substances on display
Empyrean Neuroscience launches with platform to advance pipeline of neuroactive compounds to treat central nervous system disorders. Source: Adobe Stock.

“There is an enormous medical need for safe and effective therapeutics that treat neuropsychiatric and neurologic disorders, and we believe genetic engineering provides the answer,” Usman Azam, MD, CEO of Empyrean, said in the release. “By applying our genetic engineering platform to make precise modifications to the genomes of fungi and plants, we can change the amount and kind of neuroactive small molecules they produce, with the goal of developing safe and effective treatments for difficult-to-treat diseases of the CNS.”

The company’s developmental pipeline includes neuroactive compounds such as N,N-Dimethyltryptamine for the potential treatment of major depressive disorder, PTSD, neurologic disorders, substance abuse and dependence, and chronic pain, the release stated. Empyrean’s first genetically engineered encapsulated mushroom drug product is currently being studied.

As part of its genetic engineering platform, the company licensed CRISPR/Cas9 technology from ERS Genomics for genetic engineering applications related to its therapeutic pipeline, Empyrean said.

“Fungal alkaloids and cannabinoids have shown promise in treating depression, PTSD, anxiety and other neuropsychiatric and neurologic disorders,” Fred Grossman, DO, FAPA, Empyrean’s chief medical officer, said in the release. “We believe our approach of genetically engineering fungi and plants can improve their safety and efficacy and will ultimately help to address the substantial unmet medical need in patients who suffer from these diseases.”

 

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