https://www.mdlinx.com/internal-medicine/medical-news-article/2016/04/06/anxiety-epidemiology-stroke/6604565/?
The authors assessed the association
between anxiety and the risk of incident stroke. Anxiety disorders were
not associated with stroke in the general population study. Anxiety
symptoms were only related to stroke in the short term, which needs
further exploration.
Methods
- This population-based cohort study was based on 2 rounds of the Rotterdam Study.
- Each round was taken separately as baseline.
- In 1993 to 1995, anxiety symptoms were measured using the Hospital Anxiety and Depression Scale-Anxiety (HADS-A).
- In 2002 to 2004, anxiety disorders were assessed using the Munich version of the Composite International Diagnostic Interview.
- Participants were followed up for incident stroke until January 2012.
Results
- In the sample undergoing HADS-A (N=2625; mean age at baseline, 68.4 years), 332 strokes occurred during 32 720 years of follow-up.
- HADS-A score was not associated with the risk of stroke during complete follow-up (adjusted hazard ratio, 1.02; 95% confidence interval, 0.74–1.43; for HADS-A≥8 compared with HADS-A <8), although the authors did find an increased risk after a shorter follow-up of 3 years (adjusted hazard ratio, 2.68; 95% confidence interval, 1.33-5.41).
- In the sample undergoing the Munich version of the Composite International Diagnostic Interview (N=8662; mean age at baseline, 66.1 years), 340 strokes occurred during 48 703 years of follow-up.
- Participants with any anxiety disorder had no higher risk of stroke than participants without anxiety disorder (adjusted hazard ratio, 0.95; 95% confidence interval, 0.64-1.43).
- They also did not observe an increased risk of stroke for the different subtypes of anxiety.
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