Increased Phase Angle Reflects Improvement in Activities of Daily Living and Muscle Health in Post-Stroke Rehabilitation

 Without telling us how to improve this; TOTALLY FUCKING USELESS!

Definition:
In the context of stroke, the phase angle (PhA) is a non-invasive measure of muscle quality and cellular health derived from a bioelectrical impedance analysis (BIA) test. It reflects the integrity and function of cell membranes, indicating cellularity, fluid distribution, and overall nutritional status. A higher phase angle is generally associated with better cellular health and physical function, while a low phase angle can predict poor outcomes, such as decreased functional independence and increased nutritional risk in stroke patients.

Increased Phase Angle Reflects Improvement in Activities of Daily Living and Muscle Health in Post-Stroke Rehabilitation

Kouki Yoneda 1, Yoshihiro Yoshimura 1, Hidetaka Wakabayashi 2, Ayaka Matsumoto 1, Fumihiko Nagano 1, Sayuri Shimazu 1, Yoshifumi Kido 1, Takahiro Bise 1, Takenori Hamada 1, Ai Shiraishi 3

Affiliations 

• PMID: 41328616
 
• DOI: 10.4235/agmr.25.0083

Free article

Abstract

Background: Phase angle (PhA) reflects cellular integrity and muscle quality. However, evidence is limited regarding whether an increase in PhA is associated with improvements in activities of daily living (ADL) and skeletal muscle mass. This study aimed to investigate the association between change in PhA and prognosis in terms of ADL and skeletal muscle mass in post-stroke patients undergoing rehabilitation.

Methods: This retrospective cohort study was conducted at a convalescent rehabilitation hospital in Japan. Patients with a PhA at admission below the cutoff values (4.76° for males and 4.11° for females) were included. Patients were categorized into a PhA-increase group (>0) and a non-increase group (≤0). Outcomes included the Functional Independence Measure (FIM)-motor score and skeletal muscle mass index (SMI) at discharge. Multivariate regression was used to assess associations.

Results: A total of 253 patients were included (mean age 78.0 ± 10.9 years; 51% women). The median [IQR] PhA at admission was 3.70° [3.20, 4.10], and the median change during hospitalization was 0.00° [-0.20, 0.30]. Of these, 119 patients had increased PhA and 134 did not. Change in PhA was independently associated with higher FIM-motor scores (β = 0.078, P = 0.040) and greater SMI (β = 0.454, P < 0.001) at discharge.

Conclusions: In post-stroke patients, an increase in PhA during hospitalization was associated with better functional and muscular outcomes. PhA may therefore serve as a valuable biomarker for assessing the efficacy of rehabilitation.

Keywords: Activities of daily living; Bioelectrical impedance analysis; Phase angle; Sarcopenia; Skeletal muscle mass; Stroke rehabilitation.

Phase Angle as a Predictor of Walking Independence in Patients Undergoing Stroke Rehabilitation: A Preliminary Study

Are you that blitheringly stupid? Survivors don't want predictions; they want EXACT RECOVERY PROTOCOLS! Right now, stroke rehab is a complete failure; 10% full recovery! Why aren't you solving that problem? Predictions are fucking lazy crapola; YOU'RE FIRED!

Definition:
In the context of stroke, the phase angle (PhA) is a non-invasive measure of muscle quality and cellular health derived from a bioelectrical impedance analysis (BIA) test. It reflects the integrity and function of cell membranes, indicating cellularity, fluid distribution, and overall nutritional status. A higher phase angle is generally associated with better cellular health and physical function, while a low phase angle can predict poor outcomes, such as decreased functional independence and increased nutritional risk in stroke patients.

 Phase Angle as a Predictor of Walking Independence in Patients Undergoing Stroke Rehabilitation: A Preliminary Study

 Naoya IKEDA, PT and Yasuhiro MINAMIMURA, PT Department of Rehabilitation, Saiseikai Kibi Hospital, Japan 

 ABSTRACT. 

Objectives: 

This study examined the relationship between phase angle (PhA), an indicator of muscle quality, and independent walking in stroke patients. The objective was to determine the predictive value of a PhA at admission for walking independence at discharge. 

Methods: 

This study included 220 stroke patients (121 males, 99 females), categorized based on their functional independence measure (FIM) mobility scores at discharge: independent (FIM ≥6; n = 100) and dependent (FIM ≤5; n = 120). Logistic regression analysis assessed whether PhA at admission predicted ambulatory independence at discharge. Additionally, receiver-operating characteristic curve analysis determined optimal cutoff values. 

Results: 

Logistic regression analysis showed that PhA at admission and the National Institutes of Health Stroke Scale (NIHSS) were sig nificant predictors of independent walking. The optimal cutoff values for PhA were determined to be 4.35° for men and 4.1° for women. Similarly, the cutoff scores for the NIHSS were 7.5 points for men and 5.5 points for women. 

Conclusions: 

In stroke patients, PhA and NIHSS at admission were significantly associated with ambulatory independence at discharge. Evaluation of PhA and NIHSS at admission may be useful for more accurate prediction of gait outcomes. Key words: Stroke, Phase angle, Muscle quality, Walking