Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label research incompetence?. Show all posts
Showing posts with label research incompetence?. Show all posts

Monday, February 9, 2026

Natural History of Stroke: Cause and Development

The natural response of stroke survivors is: Get stroke solved to 100% recovery! 

If you can't see and work on that, you're dumber than a bag of rocks!

Oops, I'm not being humble enough for the failed stroke medical 'professionals' out there! The scare quotes are there because they are true. 

There are hundreds if not thousands of pieces of research needing followup and YOU DON'T KNOW ABOUT THEM?

  • human testing (256 posts to March 2011)
  • further research (301 posts to August 2012)
  • Natural History of Stroke: Cause and Development

    ClinicalTrials.gov IDNCT00009243
    SponsorNational Institute of Neurological Disorders and Stroke (NINDS)
    Information Provided byLawrence L Latour, Ph.D.
    Study Start (Actual)2001-01-26
    Enrollment (Estimated)4000
    Study TypeObservational
    Last Update Posted2026-01-12

    Study Overview

    Brief Summary

    The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations. It will 1) establish a registry of patients with cerebrovascular disease (stroke); 2) characterize the natural history of acute stroke and transient ischemic attacks (TIA)-an interruption of blood flow to the brain that causes stroke symptoms for a short period of time); and 3) evaluate the data to generate ideas for future studies(WOW! Not being up-to-date on research just completely proved your INCOMPETENCY!). Patients 18 years of age or older with suspected acute stroke or TIA may be eligible for this study. Subjects will be recruited from patients who present with stroke at the emergency department of Suburban Hospital in Bethesda, Maryland. The study will gather data collected from diagnostic and laboratory tests the patient undergoes as part of standard medical care, including findings of medical and neurological examinations and other tests. In addition, studies will be done for research purposes only to gather data about stroke and TIA. These may include the following: * Blood and urine tests not more than 2 tablespoons of blood will be drawn for various tests. * Electrocardiogram (EKG) (heart tracing)-electrodes placed on the chest wall detect the heartbeat and heart rhythm. * Computed tomography (CT) scan of the head-specialized X-rays are used to obtain images of the brain. * Magnetic resonance imaging (MRI) of the brain-a strong magnetic field and radio waves are used to produce images that provide information about the brain tissue and blood vessels. * Transcranial Doppler (TCD)-sound waves are used to image the arteries of the brain and neck. * Echocardiogram-sound waves are used to image the heart and evaluate heart function. Patients may be asked to return to Suburban Hospital for follow-up testing in 1, 3, and/or 12 months, when some of these tests may be repeated to assess changes over time ...

    Contacts and Locations

    Contact Information

    Study Contact

    NameNicole L Peterkin

    Phone(301) 435-2395

    United States Locations

    District of Columbia

    Washington D.C., District of Columbia, United States 20010
    Medstar Washington Hospital CenterBethesda, Maryland, United States 20814Suburban Hospital - Johns Hopkins Medicine

    Eligibility Criteria

    • INCLUSION CRITERIA:

    In order to be eligible to participate in this study, an individual must meet all of the following criteria:

    1. Aged >=18
    2. Presented to participating study site (ED, ICU, or inpatient unit) with or at risk of acute stroke, TIA, or other disturbances of cerebrovascular circulation

    EXCLUSION CRITERIA:

     

    An individual who meets any of the following criteria will be excluded from participation in this study:

    1. Subjects with contraindication to MRI scanning will be excluded from any testing which involves the use of MRI. The contraindications include subjects with the following devices or conditions:

      • Central nervous system aneurysm clips
      • Implanted neural stimulator
      • Implanted cardiac pacemaker or defibrillator
      • Cochlear implant
      • Ocular foreign body (e.g. metal shavings)
      • Insulin pump
      • Metal shrapnel or bullet
      • Any implanted device that is incompatible with MRI

      Subjects with a condition precluding entry in the scanner (e.g. morbid obesity, Claustrophobia, etc.) will not be included in the MRI portion of this study.

    2. Pregnancy

    Ages Eligible for Study

    Minimum Eligible Age Not available

    Maximum Eligible Age Elderly

    Age Groups adult, older_adult

    Eligible Sexes all

    Accepts Healthy VolunteersNo

    Study Contact Backup

    NameLawrence L Latour, Ph.D.

    Phone(301) 435-2395

    Saturday, November 25, 2023

    IC3 protocol: a longitudinal observational study of cognition after stroke using novel digital health technology

    You do realize that it is much more important to solve cognition problems than to assess them. This DOES NOTHING to get survivors recovered! I'd have you all fired and I'm a nice guy except when it comes to stroke incompetence.

     IC3 protocol: a longitudinal observational study of cognition after stroke using novel digital health technology

    Dragos-Cristian Gruia1,2,

    1. William Trender1,
    2. Peter Hellyer3,
    3. Soma Banerjee1,2,
    4. Joseph Kwan1,2,
    5. Henrik Zetterberg4,5,6,7,8,9,
    6. Adam Hampshire1,
    7. Fatemeh Geranmayeh1,2
    1. Correspondence to Dr Fatemeh Geranmayeh; fatemeh.geranmayeh00@imperial.ac.uk

    Abstract

    Introduction Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors. These deficits negatively impact recovery and therapy engagement, and their treatment is consistently rated as high priority by stakeholders and clinicians. Although clinical guidelines endorse cognitive screening for poststroke management, there is currently no gold-standard approach for identifying cognitive deficits after stroke, and clinical stroke services lack the capacity for long-term cognitive monitoring and care. Currently, available assessment tools are either not stroke-specific, not in-depth or lack scalability, leading to heterogeneity in patient assessments.

    Methods and analysis To address these challenges, a cost-effective, scalable and comprehensive screening tool is needed to provide a stroke-specific assessment of cognition. The current study presents such a novel digital tool, the Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3), designed to detect both domain-general and domain-specific cognitive deficits in patients after stroke with minimal input from a health professional. To ensure its reliability, we will use multiple validation approaches, and aim to recruit a large normative sample of age-matched, gender-matched and education-matched UK-based controls. Moreover, the IC3 assessment will be integrated within a larger prospective observational longitudinal clinical trial, where poststroke cognition will be examined in tandem with brain imaging and blood biomarkers to identify novel multimodal biomarkers of recovery after stroke. This study will enable deeper cognitive phenotyping of patients at a large scale, while identifying those with highest risk of progressive cognitive decline, as well as those with greatest potential for recovery.

    Ethics and dissemination This study has been approved by South West—Frenchay Research Ethics Committee (IRAS 299333) and authorised by the UK’s Health Research Authority. Results from the study will be disseminated at conferences and within peer-reviewed journals.

    Trial registration number NCT05885295. Stage: Pre-results.

    https://creativecommons.org/licenses/by/4.0/

    This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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