Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label specific. Show all posts
Showing posts with label specific. Show all posts

Saturday, February 23, 2019

One more reason to get moving

One more reason to blame your doctor for not getting you 100% recovered. Make sure you tell that to your doctor in person. You need to see the reaction when you call out their incompetency. 

One more reason to get moving


Rosemary Black, for MDLinx | February 21, 2019
You already know that exercise can reduce the risk of everything from type 2 diabetes and heart disease to depression. Now, it turns out that being more physically active may protect against dementia as well. Older adults who either engage in daily exercise or just do everyday tasks, such as housework, may maintain more of their thinking skills and memory than their less active counterparts—and that holds true even if they have the brain lesions or biomarkers that are linked to dementia, according to a recently published study in Neurology.

Older adults who either engage in daily exercise or just do everyday tasks, such as housework, may maintain more of their thinking skills and memory than their less active counterparts.
In the study, researchers assessed 454 older adults (191 with dementia and 263 without dementia) who underwent physical examination and cognitive testing annually for 20 years. All participants consented to brain donation upon their passing (mean age at death: 91 years). Participants’ physical activity was monitored with an accelerometer. Upon collection and analysis of individualized movement data, the researchers calculated an average daily activity score for each participant.
When scientists examined the decedents’ brains for lesions and biomarkers of dementia and Alzheimer’s disease, they found a link between a higher level of physical activity and better cognition that was independent of the presence of biomarkers of dementia, Alzheimer’s disease, or related cognitive disorders.
The study authors concluded that, “Physical activity in older adults may provide cognitive reserve to maintain function independent of the accumulation of diverse brain pathologies. Further studies are needed to identify the molecular mechanisms underlying this potential reserve and to ensure the causal effects of physical activity.”(So they know nothing specific, but feel obligated to tell you this to assuage their conscience. )
Exercise is already touted for its beneficial effects on health.(Yes, we know your are touting your laziness.)
“Prior studies have indicated that higher levels of aerobic exercise, along with a diet low in saturated fat and refined sugars, combined with increased amounts of lean proteins and healthy grains and fiber, are an important component to control blood pressure and reduce cholesterol and triglycerides,” said Robert Glatter, MD, emergency physician, Lenox Hill Hospital, New York City, NY. “Keeping yourself physically active to improve cardiac fitness translates to improved vascular health, which has clear neuroprotective effects.”
As far as which types of physical activity older Americans should try to get, Dr. Glatter recommended “practical interventions” such as taking the stairs instead of using the elevator or escalator. Also, try walking to your destination rather than driving, he added.
“Simply taking ‘standing breaks’ at work, instead of sitting, is also going to benefit your vascular health overall, by reducing stasis and improving blood flow,” Dr. Glatter noted.
The key to enticing older people—or anyone, for that matter—to exercise is to “find things they enjoy doing,” said Scott Going, PhD, exercise physiologist and professor, Department of Nutritional Sciences, The University of Arizona College of Agriculture and Life Sciences, Tucson, AZ. “Ask what do they like to do? Maybe they enjoy social dancing, or moving around the yard doing chores,” he said. It doesn’t matter what they do, as long as it’s on a regular basis, he added. Even low-intensity exercise can be beneficial.
It's key to remember that exercise needn’t take place at a gym, explained Shawn Anthony, MD, sports medicine surgeon, Mount Sinai West, New York City, NY. “Any time not spent sitting can be made part of an exercise program,” he said. “Body weight exercises are a great way to build core and muscle strength, improve balance, and gain benefits for cardiovascular health.”
Simple exercises may include heel-toe walking, one-leg balancing, and standing marches, he added.
“Exercises can be performed while waiting in line at the supermarket or during TV commercial breaks,” Dr. Anthony said. “Everyday house chores like laundry and cleaning also are efficient ways to keep moving.” (My God, what fucking lazy incomparable stupidity.)
About 30 minutes a day of exercise is recommended, and it can be broken up into 5 and 10-minute increments, Dr. Going said.
Those who are wheelchair-bound can do upper body activities, he added. The American Academy of Retired Persons offers suggestions for exercise and fitness routines for older adults as well.
According to Dr. Glatter, while exercise is important, there are other factors that come into play as well when weighing risk factors for Alzheimer’s disease and dementia.
“The contributions of adequate sleep, treating depression, and reducing isolation may be equally important as we age, since they ultimately affect blood pressure and lipid profile,” he said. “Keep in mind that one of the key aspects of reducing the risk for dementia centers around vascular health. Along with aerobic exercise, your blood pressure and lipid profile are important determinants that influence the pliability and reduce stiffness in small blood vessels.”
 

Wednesday, July 19, 2017

A heart-healthy diet may lower risk of cognitive impairment in old age, studies suggest

Are you getting specifics on your diet protocols from your hospitals? Or do you get generalized crap statements like follow the DASH or Mediterranean diets? Nothing here tells me SPECIFICS. So this is fucking useless.
http://www.news-medical.net/news/20170718/A-heart-healthy-diet-may-lower-risk-of-cognitive-impairment-in-old-age-studies-suggest.aspx
A diet designed to improve cardiovascular health is associated with improved cognitive maintenance in old age, say researchers.
The finding comes from four large-scale, population-based studies that were reported on at the 2017 Alzheimer’s Association International Conference (AAIC) in London.
Keith Fargo from the Alzheimer’s Association says: “Although the idea that a healthy diet can help protect against cognitive decline as we age is not new, the size and length of these four studies demonstrate how powerful good dietary practices may be in maintaining brain health and function.”
The Mediterranean and DASH (Dietary Approaches to Stop Hypertension) diets were originally designed to improve cardiovascular health. A combination of these diets, called the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, has also been associated with potential positive effects on cognitive function and reduced dementia risk in older people.

Image: Food examples in the Mediterranean diet. ©Foxys Forest Manufacture/ Shutterstock.com
In the Health and Retirement Study, which included almost 6,000 older adults, US researchers found that those who followed the Mediterranean diet and MIND diet were at a 30 to 35% lower risk of impaired cognition and demonstrated significant preservation of cognitive function.
Also reporting at the AAIC were researchers from the Karolinska Institute in Sweden who examined the effects of following the Nordic Diet, a traditional Scandinavian diet rich in berries, oily fish, poultry and non-root vegetables. The team found that people who stuck to the diet had improved cognitive function over people who followed a less healthy diet.
In the US-based Women’s Health Initiative Memory Study, which included more than 7,000 women, researchers found that older women who followed heart-healthy diets, particularly the MIND diet, had a significantly reduced risk of developing dementia.
Finally, Columbia University researchers reported on the effects of following a poor diet. They presented data suggesting that such diets are associated with premature brain aging and smaller brain volume as a result of inflammatory mechanisms.
Fargo says that although the studies demonstrate the powerful effects healthy eating may have on brain health, it must be understood that diet is only one aspect of the overall picture.
“Adapting our lifestyles as we get older – for example by exercising regularly, watching what we eat and engaging in lifelong learning – is important in order to maximize the potential to reduce risk of cognitive decline and dementia,” he advises.

Tuesday, May 23, 2017

The Relation of Hypertension to Performance in Immediate and Delayed Cued Recall and Working Memory in Old Age: The Role of Cognitive Reserve

You'll have to ask your doctor SPECIFICALLY how to create cognitive reserve and how to measure if you have enough to survive another stroke and prevent dementia, Not just general blathering statements. SPECIFICS.

The Relation of Hypertension to Performance in Immediate and Delayed Cued Recall and Working Memory in Old Age: The Role of Cognitive Reserve  


First Published May 15, 2017



Objective: We investigated the relation of hypertension to cognitive performance and its interplay with key markers of cognitive reserve in a large sample of older adults.  
Method: We assessed tests of immediate and delayed cued recall and working memory in 701 older adults. We measured systolic blood pressure and interviewed individuals on their education, past occupation, and cognitive leisure activity.
Results: Hypertension (≥140 mmHg) was related to lower performance in all three cognitive measures. Moderation analyses suggested that these relations were reduced in individuals with greater engaging in cognitive leisure activity. Hierarchical regression analyses showed that hypertension was not related to any of the three investigated cognitive performance measures when education, cognitive level of job, and cognitive leisure activity were simultaneously taken into account.
Discussion: The detrimental influences of hypertension on cognitive functioning in old age may be reduced in individuals with greater cognitive reserve accumulated during the life course.

Monday, February 13, 2017

Mediterranean Diet Boosts HDL Function

Pretty much useless information. They don't point to a SPECIFIC diet protocol. But it is great conscience laundering for them, thinking they are providing help.

Mediterranean Diet Boosts HDL Function

  • by
    Staff Writer, MedPage Today
  • This article is a collaboration between MedPage Today® and:
    Medpage Today

Action Points

  • Adherence to a traditional Mediterranean diet (TMD) enriched with virgin olive oil improved HDL function in humans, according to a year-long dietary study.
  • Note that the data indicated a dissociation between the effects of a TMD on HDL-C levels, which trended lower, versus effects on HDL cholesterol efflux capacity (CEC), which was significantly increased.
A Mediterranean diet rich in virgin olive oil improved high-density lipoprotein (HDL) function in individuals with high-cardiovascular risk, reported researchers.
Compared with both a traditional Mediterranean diet (TMD) enriched with nuts and a low-fat control diet, adherence to a TMD enriched with olive oil decreased cholesteryl ester transfer protein activity (relative to baseline, P=0.028), reported Montserrat Fitó, MD, PhD, coordinator of the Cardiovascular Risk and Nutrition Research Group at the Hospital del Mar Medical Research Institute in Barcelona, and colleagues.
It also increased HDL's ability to esterify cholesterol, paraoxonase-1 arylesterase activity, and HDL vasodilatory capacity (relative to control, P=0.039, P=0.012, and P=0.026, respectively), they wrote in Circulation.
"Following a Mediterranean diet rich in virgin olive oil could protect our cardiovascular health in several ways, including making our 'good cholesterol' work in a more complete way," Fitó stated in a press release.
Writing in an accompanying editorial, Daniel J. Radar, MD, of the University of Pennsylvania in Philadelphia, noted that the findings increase understanding of how dietary intervention can affect HDL functionality.
"Hernáez et al demonstrate a dissociation between the effects of a TMD on HDL-C levels (trending lower) versus on HDL CEC [cholesterol efflux capacity] (significantly higher) and greater positive effects of the TMD on CEC compared with those of a low-fat diet.
"Although efforts to promote HDL CEC through pharmacological means are still in clinical development, these results indicate that a Mediterranean diet is a practical lifestyle-focused approach to improving HDL function and has the proven benefit of reducing cardiovascular risk and the potential to reduce the progression of age-related macular degeneration. Whether promotion of HDL CEC causally contributes to the benefits of the Mediterranean diet remains to be established," he wrote online.
Fitó and colleagues randomly selected a subsample of 296 people at high risk of cardiovascular disease among those participating in the PREDIMED (PREvención con DIeta MEDiterránea) study. The participants (mean age 66) provided blood samples at both the beginning and the end of the 1-year study period. They were randomly assigned to one of three diets:
  • A traditional Mediterranean diet enriched with virgin olive oil (about 4 tablespoons) each day (n=100)
  • A traditional Mediterranean diet enriched with extra nuts (about a fistful) each day (n=100)
  • A healthy "control" diet that reduced consumption of red meat, processed food, high-fat dairy products and sweets (n=96)
Both Mediterranean diets emphasized fruits, vegetables, legumes, and whole grains, as well as moderate amounts of fish and poultry.
Using statistical analyses, Fitó's team assessed the effects of both TMDs on the role of HDL particles on reverse cholesterol transport (cholesterol efflux capacity, HDL ability to esterify cholesterol, and cholesteryl ester transfer protein activity), HDL antioxidant properties (paraoxonase-1 arylesterase activity and total HDL antioxidant capacity on low-density lipoproteins), and HDL vasodilatory capacity (HDL ability to induce the release of nitric oxide in endothelial cells).
The researchers also studied the effects of a TMD on several HDL quality-related characteristics (HDL particle oxidation, resistance against oxidative modification, main lipid and protein composition, and size distribution).
Fitó and colleagues found a decline in total cholesterol levels among those on the low-fat control diet (P=0.039 and P=0.007 relative to baseline and the TMD olive oil, respectively) -- mainly due to a decrease in LDL cholesterol levels (P=0.019 and P=0.004 relative to baseline and the TMD olive oil, respectively).
The TMD with olive oil and with nuts both increased cholesterol efflux capacity relative to baseline (P=0.018 and P=0.013, respectively), but the low-fat diet did not yield significant results.
Additionally, the content of triglycerides in HDL core decreased significantly after both the TMD olive oil and TMD nuts interventions compared with the low-fat diet (P=0.027 and P=0.035, respectively).
All three diets increased the percentage of large HDL particles (relative to baseline, P<0 .001="" p=""> Fitó and colleagues wrote they were surprised that the low-fat diet, which was rich in fruits and vegetables just like the Mediterranean diets, had a negative impact on HDL's anti-inflammatory properties.
They also discussed several possible explanations for the TMD-mediated increase in HDL functionality, including an improvement in the oxidative status of the lipoprotein and a better HDL composition profile.
Radar, too, had several theories for the differences observed between the TMD and the low-fat diet: "One possible difference is alcohol intake. The TMD participants were instructed that 'when the volunteer consumed alcohol, to moderately drink red wine (1 small glass/meal),' whereas the low-fat diet participants were given no similar instructions. Alcohol consumption is known to influence HDL-C levels and has been shown in a small experimental study to promote CEC."
The researchers concluded that "further studies are warranted to investigate the mechanism by which the TMD improves HDL function and whether these properties convey cardioprotective effects."
"Our study could be useful to remind that the Mediterranean Diet is beneficial even through unexpected mechanisms, highlighting again the importance of taking care of our cardiovascular health through a simple and cheap way such as a healthy diet," Fitó explained to MedPage Today.
Studying the cardioprotective mechanisms of an antioxidant-rich diet may contribute to the development of future therapeutic targets oriented to improve HDL functions, he added.
Study limitations were the inclusion of elderly people at high cardiovascular risk which may prevent extrapolation of the results to the general population.
Fitó noted a final limitation: "Some of the techniques used to measure HDL functions, although they were non-invasive and highly-sensitive, were in vitro simulations of processes that happen in our arteries (such as the removal of cholesterol or the ability of HDLs to induce the relaxation of blood vessels). These tests may not fully reflect the real complexity of the previous cardiovascular phenomena," he wrote to MedPage Today.

This work was funded by Agència de Gestió d'Ajuts Universitaris i de Recerca, CIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, and the Spanish Ministry of Education, Culture and Sport.
The researchers reported no financial disclosures of interest.