A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

 WOW! Crapola research; 'monitoring' NOT CURING SPASTICITY! And it's a useless observational trial. I'd fire everyone involved!

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

ClinicalTrials.gov IDNCT06055725

SponsorIpsen

Information Provided byIpsen Medical Director

Study Start (Actual)2023-11-01

Primary Completion (Estimated) 2027-11-30

Study Completion (Estimated)2027-11-30

Enrollment (Estimated)1058

Study TypeObservational

Last Update Posted2026-05-01

Brief Summary

This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain. The main aim of the study will be to find out how many of those who experience their first-ever stroke then go on to develop spasticity that would benefit from treatment with medication. Spasticity is a common post-stroke condition that causes stiff or ridged muscles. The results of this study will provide a standard guideline on the best way to monitor the development of post-stroke spasticity.

To learn more, visitClinicalTrials.gov

Validity of FuncUseRatio for ecological monitoring of functional arm use after stroke: toward precision neurorehabilitation

 Since you DID NOTHING to map EXACT recovery protocols to the deficits found; COMPLETELY FUCKING USELESS RESEARCH! You're fired! 

Comeuppance is going to be a real bitch for you when you are the 1 in 4 per WHO that has a stroke!

Validity of FuncUseRatio for ecological monitoring of functional arm use after stroke: toward precision neurorehabilitation

• Gaël Le Perf,
• Benoit Pratola,
• Denis Mottet,
• Isabelle Laffont &
• Karima Bakhti 

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Abstract

Background

The use of the paretic arm in activities of daily living after stroke is critical to prevent further decline in function over time. Accelerometers offer the opportunity to monitor arm activity during real-life daily activities in home environments. However, commonly used accelerometric metrics may be influenced by passive movements unrelated to functional arm use. In this study, we evaluate the validity of FuncUseRatio for monitoring activities of daily living after stroke.

Methods

Two experiments were conducted. Experiment 1 enrolled 23 healthy participants who performed 22 arm functional movements representative of activities of daily living. Movements of both arms were simultaneously recorded using wrist-worn accelerometers and a Vicon motion capture system allowing a direct comparison between accelerometer-derived forearm orientation and Vicon measurements (gold standard). Experiment 2 included 25 individuals after stroke who performed ecological activities (meal preparation, eating, and dressing). Arm movements were recorded using accelerometers and synchronized video analysis (ground truth), enabling comparison between accelerometer-derived FuncUseRatio and structured video-based arm-use computation.

Results

In Experiment 1, forearm orientation estimated from accelerometer data showed excellent consistency with Vicon measurements under dynamic conditions required for FuncUse computation. The intraclass correlation coefficients (ICC) were ICC(C,1) = 0.92 (95% CI 0.82–0.96, p < 0.01) for the right forearm and ICC(C,1) = 0.94 (95% CI 0.86–0.97, p < 0.01) for the left forearm, confirming strong agreement between the two systems. In Experiment 2, FuncUseRatio derived from accelerometer data demonstrated excellent agreement with the structured video-based analysis ratio, considered the ground truth, with (ICC(A,1) = 0.96, 95% CI 0.90–0.98, p < 0.01).

Conclusion

The FuncUseRatio is a valid measure for assessing functional arm use during activities of daily living in ecologically relevant settings. Its implementation may enable early detection of reduced paretic arm use, including when the patient is at home, facilitate timely reassessment to understand its underlying causes, and thereby allow the implementation of specific arm rehabilitation strategies before any decline in function or participation occurs.

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

WHAT ABSOLUTE FUCKING STUPIDITY! 'Monitoring' spasticity rather than curing it!  YOU'RE ALL FIRED FOR EXTREME INCOMPETENCE!

You don't know about this earlier research? 

30% get spasticity (28 posts to March 2016)

Proving your absolute incompetence?
A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

ClinicalTrials.gov ID NCT06055725

 Sponsor Ipsen Information Provided by Ipsen Medical Director Study Start (Actual)2023-11-01 Primary Completion (Estimated) 2027-11-03 Study Completion (Estimated)2027-11-30 Enrollment (Estimated) 1051 Study Type Observational Last Update Posted2025-08-27 

Brief Summary

This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain. The main aim of the study will be to find out how many of those who experience their first-ever stroke then go on to develop spasticity that would benefit from treatment with medication. Spasticity is a common post-stroke condition that causes stiff or ridged muscles. The results of this study will provide a standard guideline on the best way to monitor the development of post-stroke spasticity.

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

 

For FUCKING STUPIDITY'S SAKE!  Monitoring DOES NOTHING FOR RECOVERY! 

I'd have all of you fired for extreme stupidity!

Send me personal hate mail on this: oc1dean@gmail.com. I'll print your complete statement with your name and my response in my blog. Or are you afraid to engage with my stroke-addled mind? No excuses are allowed! You're medically trained; it should be simple to precisely state EXACTLY HOW monitoring gets spasticity cured with NO EXCUSES! Your definition of competence in stroke is obviously much lower than stroke survivors' definition of your competence! Swearing at me is allowed, I'll return the favor. Don't even attempt to use the excuse that brain research is hard.

Have you ever thought' 'Just maybe survivors want spasticity cured?' Or doesn't that even compute?

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its DevelopmentClinicalTrials.gov IDNCT06055725

ClinicalTrials.gov IDNCT06055725

SponsorIpsen

Information Provided byIpsen Medical Director

Study Start (Actual)2023-11-01

Primary Completion (Estimated) 2027-11-03

Study Completion (Estimated)2027-11-30

Enrollment (Estimated)1051

Study TypeObservational

Last Update Posted2025-07-30

Last Update Posted2025-07-30

Study Overview

Brief Summary

This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain. The main aim of the study will be to find out how many of those who experience their first-ever stroke then go on to develop spasticity that would benefit from treatment with medication. Spasticity is a common post-stroke condition that causes stiff or ridged muscles. The results of this study will provide a standard guideline on the best way to monitor the development of post-stroke spasticity.ClinicalTrials.gov