Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, December 4, 2024

Understanding the biological effects of hypoxia in ischemic stroke: implications for rehabilitation and recovery


Nothing in this earlier research tells me if ANY RECOVERY WAS ACHIEVED. Useless. 

Hypoxic postconditioning promotes neurogenesis by modulating the metabolism of neural stem cells after cerebral ischemia September 2021

So, ask your competent? doctor if this latest research proves viability.

 Understanding the biological effects of hypoxia in ischemic stroke:
implications for rehabilitation and recovery

Vol.:(0123456789)Discover Medicine (2024) 1:130 | https://doi.org/10.1007/s44337-024-00161-0

Nicholas Aderinto1 · Gbolahan Olatunji2 · Emmanuel Kokori3 · Bonaventure Ukoaka 4 ·
Adetola Emmanuel Babalola5 · Ikponmwosa Jude Ogieuhi6 · Abdulrahmon Moradeyo 1 · Ismaila Ajayi Yusuf7 ·
Apampa Oluwatobiloba Oluwatomisin8 · Adefusi Temiloluwa Oluwakorede9 · Oluwatobi Omoworare10 ·
Yewande Abigail Adebayo11
Received: 20 July 2024 / Accepted: 22 November 2024
© The Author(s) 2024 OPEN

Abstract

Ischemic stroke can leave patients with lasting disabilities. Rehabilitation is crucial, but new approaches are needed. One promising avenue is hypoxia exposure therapy. This involves controlled exposure to low oxygen levels. While it may sound counterintuitive, this approach triggers the brain to adapt. Studies suggest hypoxia stimulates the growth of new blood vessels, boosting oxygen delivery to the damaged area. Additionally, it may promote neuroplasticity, the brain’s ability to reorganize and form new connections. This can lead to the creation of new nerve cells, potentially replacing those lost in the stroke. Furthermore, hypoxia exposure might help regulate inflammation, a key contributor to stroke damage. Early research, particularly with intermittent hypoxia training, shows promise for improved motor function recovery. However, challenges remain. Stroke severity, location, and individual health vary greatly, requiring personalized treatment plans.
Determining the optimal dose, timing, and frequency of hypoxia exposure is crucial for maximizing benefits. Additionally, the precise mechanisms by which hypoxia aids recovery need further investigation. Future research will focus on tailoring protocols to individual patients, exploring combinations with other rehabilitation methods, and conducting large-scale trials to solidify the safety and effectiveness of hypoxia therapy.
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