Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, June 15, 2025

Brain Adapts to Neuron Loss Through Rapid Rewiring

 Ask your competent? doctor EXACTLY HOW TO ENGAGE THIS post stroke!

This is what your doctor is up against, I'd suggest charging your hospital $1000 a dead neuron, that might get them to solve stroke, nothing else gets them off their asses!

 In each  untreated minute,

1.9 million neurons die

14 billion synapses die

12 km (7.5 miles) of myelinated fibers die

brain ages 3.6 years each hour without treatment

If Pedro Bach-y-Rita can recover you can solve most stroke problems.

Pedro Bach-y-Rita had a stroke in 1958, it destroyed a large portion of his brain stem and yet over the last 7 years of his life he recovered most of his faculties.  We have the methods he used, your doctor should be able to modify them to help you. If you have a competent doctor!

Brainstem stroke recovery How Pedro recovered in here.

And negative Nellie here, don't listen to her, she knows nothing!

Brain can't rewire itself: A new study on brain damage and recovery

The latest here:

Brain Adapts to Neuron Loss Through Rapid Rewiring

Summary: New research shows that the brain’s cortex can rapidly reorganize itself after losing neurons, allowing other nerve cells to take over lost functions. Scientists studied neural networks in the auditory cortex and found that although sound-processing patterns were briefly disrupted, the brain formed nearly identical patterns within days.

Neurons previously uninvolved in processing stimuli stepped in to compensate for the loss. This adaptive mechanism could help explain how the brain maintains function during aging or in diseases like Alzheimer’s and Parkinson’s.

Key Facts:

  • Rapid Reorganization: Neural networks re-establish activity patterns just days after neuron loss.
  • Functional Compensation: Unused neurons can adapt to take over the roles of lost cells.
  • Clinical Implication: May explain brain resilience in aging and neurodegenerative conditions.

Source: Johannes Gutenberg University Mainz

How the brain largely maintains its function when neurons are lost—this is what researchers at the University Medical Center Mainz, the Frankfurt Institute for Advanced Studies (FIAS) and Hebrew University (Jerusalem) have deciphered.

They show that neuronal networks in the cerebral cortex reorganize within a short period of time, with other nerve cells taking over the tasks of the lost neurons.

This shows a brain.
Nerve cells (neurons) are the most important building blocks of the brain. Credit: Neuroscience News

These findings could form the basis for future research into natural aging processes and neurodegenerative diseases such as Alzheimer’s or Parkinson’s.

The study is published in the journal Nature Neuroscience.

Nerve cells (neurons) are the most important building blocks of the brain.

They form the basis for all mental and physical functions such as thinking, feeling, movement, and perception. In the course of life, nerve cells in the brain can be lost for various reasons: They die off due to age-related processes, are damaged by toxins such as alcohol, or neurodegenerative diseases such as Alzheimer’s and Parkinson’s lead to a more rapid progressive loss of neurons.

While most body organs regularly replace old or damaged cells with new ones in order to maintain their organ function, new neurons only form in certain regions of the brain. In the cerebral cortex, which is responsible for complex thought processes and perception, the ability to form new neurons is very limited in adulthood.

“Nevertheless, clinical studies have shown that cortical brain function is often surprisingly resistant to the loss of neurons that occurs in the course of aging or neurodegenerative diseases,” explains Simon Rumpel, head of the Systems Neurophysiology research group at the Institute of Physiology at the University Medical Center Mainz.

Until now, it was not known how the brain can compensate for the loss of nerve cells and maintain its function. To find this out, the research team used an animal model to investigate the neuronal networks in the auditory cortex, which is responsible for processing acoustic stimuli.

The perception of sounds is based on activity patterns that are triggered in the brain by acoustic stimuli. These patterns are very complex. Ph.D. student Bastian Eppler and Senior Fellow Matthias Kaschube at FIAS contributed significantly to the analysis of these data and the interpretation of the results with their expertise.

The researchers found that the activity patterns initially destabilize when the loss of a few specific nerve cells is deliberately induced. This indicates that the neuronal network responsible for sound perception is in a delicate balance.

After just a few days, very similar activity patterns form again. The nerve cells that were not previously activated by the acoustic stimuli now acquire the ability to take the place of the lost neurons.

“We assume that this newly discovered neuronal mechanism plays an important role in the loss of nerve cells in natural aging processes as well as in neurodegenerative diseases,” says Rumpel. Future research efforts could aim to support this neuronal reorganization.

About this neuroscience research news

Author: Simon Rumpel
Source: Johannes Gutenberg University Mainz
Contact: Simon Rumpel – Johannes Gutenberg University Mainz
Image: The image is credited to Neuroscience News

Original Research: Open access.
Homeostasis of a representational map in the neocortex” by Simon Rumpel et al. Nature Neuroscience

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