Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, August 10, 2025

Crocus sativus(saffron) and Neurological Health: A Review on Depression and Impaired Neurogenesis

 I'm sure your competent? doctor never got further research going on saffron almost a decade ago, right? Oh NO, you DON'T have a functioning stroke doctor, do you? Well, so what, they are still getting paid while being incompetent. Until we get pay for performance our doctors will never improve!

  • saffron (10 posts to January 2017)

    • Crocus sativus and Neurological Health: A Review on Depression and Impaired Neurogenesis


    Abstract

    Crocus sativus (saffron) is a valuable medicinal plant with a rich phytochemical profile, including bioactive carotenoids, flavonoids, and terpenoids. The key constituents of saffron-crocin, crocetin, picrocrocin, and safranal-exhibit potent neuroprotective properties, with crocin, a water-soluble carotenoid, playing a crucial role in promoting neurogenesis and mitigating depressive symptoms. Depression, affecting approximately 280 million individuals globally (WHO, 2023), is closely associated with impaired neurogenesis, highlighting the need for novel treatment strategies. Crocus sativus, particularly in its nanotherapeutic form, offers promise in the treatment of depression by effectively crossing the blood-brain barrier and modulating neurotransmitter systems. In addition to its carotenoids, saffron contains flavonoids, such as kaempferol and quercetin derivatives, which contribute to its antioxidant and anti-inflammatory activities. This review explores the phytochemical composition of Crocus sativus, its role in neurogenesis, and its potential as a therapeutic agent for depression and neurodegenerative disorders.

    Keywords: Crocin; crocetin; depression; neurogenesis; saffron; safranal..

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