http://www.ncbi.nlm.nih.gov/pubmed/26557863
Abstract
Objective.
The objective is to observe whether the traditional Chinese medicine
(TCM) Nao-Xue-Shu oral liquid improves aphasia of mixed stroke. Methods.
A total of 102 patients with aphasia of mixed stroke were divided into
two groups by a single blind random method. The patients treated by
standard Western medicine plus Nao-Xue-Shu oral liquid (n = 58) were
assigned to the treatment group while the remaining patients treated
only by standard Western medicine (n = 58) constituted the control
group. Changes in the Western Aphasia Battery (WAB), Modified Rankin
Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), and
hemorheology parameters were assessed to evaluate the effects of the
treatments. Results. Excluding the patients who dropped out, 54 patients
in the treatment group and 51 patients in the control group were used
to evaluate the effects. Significant and persistent improvements in the
WAB score, specifically comprehension, repetition, naming, and
calculating, were found in the treatment group when the effects were
evaluated at the end of week 2 and week 4, respectively, compared with
baseline. The naming and writing scores were also improved at the end of
week 4 in this group. The comprehension and reading scores were
improved at the end of week 4 in the control group compared with the
baseline, but the improvements were smaller than those in the treatment
group. The percentages of patients at the 0-1 range of mRS were
increased at the end of week 2 and week 4 in both groups, but the
improvements in the treatment group were much larger than those in the
control group. Greater improvements in the NIHSS scores and the
hemorheology parameters in the treatment group were also observed
compared with the control group at the end of week 2 and week 4.
Conclusion. Nao-Xue-Shu oral liquid formulation improved aphasia in
mixed stroke patients and thus might be a potentially effective drug for
treating stroke aphasia.
- PMID:
- 26557863
- [PubMed]
- PMCID:
- PMC4629027
No comments:
Post a Comment