http://journals.lww.com/jtrauma/Abstract/publishahead/Early_feeds_not_force_feeds___enteral_nutrition_in.99541.aspx
Azim, Asad MD; Haider, Ansab A. MD; Rhee, Peter MD, MPH; Verma, Ket MD; Windell, Elizabeth MD; Orouji Jokar, Tahereh MD; Kulvatunyou, Narong MD; Meer, Mary RD, CNSC; Latifi, Rifat MD; Joseph, Bellal MD
Published Ahead-of-Print
BACKGROUND: Brain Trauma Foundation guidelines recommend
the early use of enteral nutrition to optimize recovery following
traumatic brain injury (TBI). Our aim was to examine the effect of early
feeds (<=24 hours) on clinical outcomes after TBI.
MATERIALS: We performed a 3-year retrospective study of
patients with severe TBI (GCS<8) who were intubated, admitted to the
ICU, and received tube feeds. Early tube feeds (Early-TF) was defined as
initiation of tube feeds within 24 hours, while Late tube feeds
(Late-TF) was defined as initiation of tube feeds after 24 hours.
Outcome measures included pneumonia rates, days on ventilator, hospital
and ICU stay, and mortality rates.
RESULTS: A total of 90 patients (Early-TF: 58, Late-TF:
32) were included of which 73.3% were male, mean age was 42+/-20 years,
and median h-AIS was 4 [3-5]. There was no difference in age (p=0.1),
h-AIS (p=0.5), or admission GCS (p=0.9) between the 2 groups. Patients
with Early-TF were associated with higher no of ICU days (p=0.03) and
higher pneumonia rates (p=0.04) but there was no significant difference
in mortality (p=0.44) as compared to those who underwent Late-TF.
CONCLUSION: Although early tube feeds are known to
improve outcomes in TBI patients, our data suggests that early feeds in
TBI patients are associated with higher rates of pneumonia and greater
hospital resource utilization.
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