Prediction of late seizures after ischemic stroke using cognitive scores

 

Are you that blitheringly stupid? Survivors don't want predictions; they want EXACT RECOVERY PROTOCOLS! Right now, stroke rehab is a complete failure; 10% full recovery! Why aren't you solving that problem? Predictions are fucking lazy crapola; YOU'RE FIRED!

You've known of seizures for years, PREVENT THEIR OCCURENCE! At least leaders would do that. I guess you're not leadership material, just a mouse!

We've known of this problem a long time. Provide solutions you blithering idiots!

10% seizures post stroke (19 posts to April 2017)

5% epileptic seizures after stroke (10 posts to April 2021)

epileptic seizures (6 posts to December 2015)

post-stroke epilepsy (14 posts to December 2016) 

The latest here:

Prediction of late seizures after ischemic stroke using cognitive scores

• Hiroya Ohara, 
• Hironori Shimizu, 
• Masami Yamanaka, 
• Nanami Yamada, 
• Naoya Kikutsuji, 
• Ryuhei Miyoshi, 
• Hiromi Kanesaki, 
• Takahiro Kanda, 
• Keisuke Honda, 
• Masako Kinoshita & 
• Kazuma Sugie 

BMC Neurology volume 25, Article number: 410 (2025) Cite this article

Abstract

Background

Late seizures are well-known sequelae after stroke. Previous history of stroke and dementia is common etiology of epilepsy, however, the effect of cognitive impairment on late seizures has not been fully investigated. We investigated the clinical significance of cognitive scores in predicting the occurrence of post-stroke late seizures.

Methods

Adult patients with acute cerebral infarction were analyzed. Their cognitive function was evaluated using the Addenbrooke’s Cognitive Examination (ACE)-III and the Japanese version of Montreal Cognitive Assessment (MoCA-J) within two weeks after stroke. Factors associated with late seizures and accuracy of cognitive scores to predict late seizures were analyzed.

Results

Of 45 patients enrolled (28 males, age 77.2 ± 8.5 years, mean ± SD), eight patients had late seizures within 123.8 ± 126.5 days after cerebral infarction. Cognitive evaluation was performed at 8.0 ± 3.9 days. ACE-III and MoCA-J scores were significantly lower in patients with late seizures than in those without late seizures (ACE-III: 27.5 ± 17.3 vs. 59.1 ± 27.2, MoCA-J: 7.6 ± 5.9 vs. 15.4 ± 8.6, p < 0.05, unpaired t-test). Receiver operating characteristic curve analysis revealed that area under curve of ACE-III was larger than that of MoCA-J and size of cerebral infarction. The optimum cut-off scores of ACE-III were ≤ 58.5 (Sensitivity: 1.00, specificity: 0.62) and ≤ 45.0 (0.88, 0.73). Kaplan-Meier estimates showed that each cut-off score significantly associated with late seizures. Sizes of infarcts and of cortical lesion were not significantly different between patients with and without late seizures. ROC curve and Kaplan-Meier survival analyses showed a significant association between size of infarct and late seizures, however, ACE-III scores more strongly associated with late seizures than the size of infarct did.

Conclusion

Cognitive scores, especially ACE-III, within two weeks after cerebral infarction can be useful for predicting post-stroke late seizures.