Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label take charge. Show all posts
Showing posts with label take charge. Show all posts

Tuesday, December 1, 2020

Applying the Knowledge-to-Action Framework to Implement Gait and Balance Assessments in Inpatient Stroke Rehabilitation

 This to me indicates that the top down approach is completely wrong, you give the survivors the protocols that are out there with efficacy ratings and the survivors give them to the therapists and doctors to implement.  Survivors would ensure that they get the protocols they need and if they don't exist the doctors and therapists are in charge of getting them created.  The current situation of non-existent stroke protocols is the result of nobody taking charge. Survivors would take charge since their recovery hangs in the balance. 

Survivors don't give a fuck about assessments, they want the real thing; PROTOCOLS THAT DELIVER RECOVERY.

Applying the Knowledge-to-Action Framework to Implement Gait and Balance Assessments in Inpatient Stroke Rehabilitation

Published:November 26, 2020DOI:https://doi.org/10.1016/j.apmr.2020.10.133

This paper is only available as a PDF. To read, Please Download here.

Abstract

Objective

The overall objectives of this project were to implement and sustain use of a gait assessment battery (GAB) that included the Berg Balance Scale, 10 Meter Walk Test, and 6 Minute Walk Test during inpatient stroke rehabilitation. The study objective was to assess the impact of the study intervention on clinician adherence to the recommendations and its impact on clinician perceptions and the organization.

Design

Pre and post-training intervention study.

Setting

Subacute inpatient rehabilitation facility.

Participants

Six Physical therapists and two physical therapist assistants.

Intervention.

The intervention comprised a bundle of activities including co-developing and executing the plan with clinicians and leaders. The multi-component implementation plan was based on the Knowledge-to-Action Framework, and included implementation facilitation, implementation leadership, and a bundle of knowledge translation interventions that targeted barriers. Implementation was an iterative process in which results from one implementation phase informed planning of the next phase.

Main Outcome Measures.

Clinician administration adherence, surveys of perceptions, and organizational outcomes.

Results

Initial adherence to the GAB was 46% and increased to >85% after 6 months. These adherence levels remained consistent 48 months after implementation. Clinician perceptions of measure use were initially high (>63%), with significant improvements in knowledge and use of one measure after implementation.

Conclusions

We successfully implemented the assessment battery with high levels of adherence to recommendations, likely as a consequence of using the bundle of knowledge translation activities, facilitation, and use of a framework to co-develop the plan. These changes in practice were sustainable, as determined by a 4-year follow-up.
 

Monday, October 12, 2020

A systematic review of bilateral upper limb training devices for poststroke rehabilitation

8 years. WHAT EXACTLY DID YOUR HOSPITAL DO WITH THIS?

Do you prefer your hospital incompetence NOT KNOWING? OR NOT DOING?

You will have to take charge, your hospital is a complete failure.

 

A systematic review of bilateral upper limb training devices for poststroke rehabilitation

2012, Stroke research and treatment

 

 
 A.(Lex)E.Q.vanDelden, 1
C.(Lieke)E.Peper, 1
GertKwakkel, 1,2
andPeterJ.Beek  1
1 Research Institute MOVE, Faculty of Human Movement Sciences, VU University Amsterdam, Van der Boechorststraat 9,1081 BT Amsterdam, The Netherlands
 2 Research Institute MOVE, Department of Rehabilitation Medicine, VU University Medical Center, De Boelelaan 1117,1081 HV Amsterdam, The Netherlands
Correspondence should be addressed to A. (Lex) E. Q. van Delden, l.van.delden@vu.nlReceived 20 July 2012; Accepted 8 October 2012Academic Editor: Stefano PaolucciCopyright © 2012 A. (Lex) E. Q. van Delden et al. This is an open access article distributed under the Creative CommonsAttribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work isproperly cited.

Introduction

. In stroke rehabilitation, bilateral upper limb training is gaining ground. As a result, a growing number of mechanicaland robotic bilateral upper limb training devices have been proposed.
 Objective
. To provide an overview and qualitative evaluation of the clinical applicability of bilateral upper limb training devices.
 Methods
. Potentially relevant literature was searched in the PubMed, Web of Science, and Google Scholar databases from 1990 onwards. Devices were categorized as mechanical or robotic(according to the PubMed MeSH term of robotics).
 Results
. In total, 6 mechanical and 14 robotic bilateral upper limb training devices were evaluated in terms of mechanical and electromechanical characteristics, supported movement patterns, targeted partand active involvement of the upper limb, training protocols, outcomes of clinical trials, and commercial availability.
 Conclusion
.Initial clinical results are not yet of such caliber that the devices in question and the concepts on which they are based are firmly established. However, the clinical outcomes do not rule out the possibility that the concept of bilateral training and the accompanied devices may provide a useful extension of currently available forms of therapy. To actually demonstrate their(surplus)value, more research with adequate experimental, dose-matched designs, and sufficient statistical power are required.

Thursday, May 21, 2015

Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice

Is this enough evidence to create clinical trials in humans? Whom can we ask that question of? There is no one because no one is in charge of stroke. . Because every stroke professional in the world is waiting for SOMEONE ELSE TO SOLVE THE PROBLEM.
Three years ago this was reported;

GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice

yet we are no farther along in this because why?

http://onlinelibrary.wiley.com/doi/10.1111/jnc.13169/abstract 
  1. Yazhou Li1,†,*,
  2. Miaad Bader2,†,
  3. Ian Tamargo1,
  4. Vardit Rubovitch2,
  5. David Tweedie1,
  6. Chaim G. Pick2,3,‡ and
  7. Nigel H. Greig1,‡,*
DOI: 10.1111/jnc.13169



Abstract

Traumatic brain injury (TBI), a brain dysfunction for which there is no present effective treatment, is often caused by a concussive impact to the head and affects an estimated 1.7 million Americans annually. Our laboratory previously demonstrated that exendin-4, a long-lasting glucagon-like peptide 1 receptor (GLP-1R) agonist, has neuroprotective effects in cellular and animal models of TBI. Here, we demonstrate neurotrophic and neuroprotective effects of a different GLP-1R agonist, liraglutide, in neuronal cultures and a mouse model of mild TBI (mTBI). Liraglutide promoted dose-dependent proliferation in SH-SY5Y cells and in a GLP-1R over-expressing cell line at reduced concentrations. Pretreatment with liraglutide rescued neuronal cells from oxidative stress- and glutamate excitotoxicity-induced cell death. Liraglutide produced neurotrophic and neuroprotective effects similar to those of exendin-4 in vitro. The cAMP/PKA/pCREB pathway appears to play an important role in this neuroprotective activity of liraglutide. Furthermore, our findings in cell culture were well-translated in a weight-drop mTBI mouse model. Post-treatment with a clinically relevant dose of liraglutide for 7 days in mice ameliorated memory impairments caused by mTBI when evaluated 7 and 30 days post trauma. These data cross-validate former studies of exendin-4 and suggest that liraglutide holds therapeutic potential for the treatment of mTBI.



Tuesday, August 19, 2014

Targeted stimulation of specific brain cells boosts stroke recovery in mice

So who is going to take charge of getting this into human clinical trials? We know it is not going to be the ASA, NSA or WSO because obviously their boards of directors have no intention of ever solving any stroke problem.
Only a GREAT STROKE ASSOCIATION will ever tackle all the hardest problems in stroke.
http://scopeblog.stanford.edu/2014/08/19/targeted-stimulation-of-specific-brain-cells-boosts-stroke-recovery-in-mice/