Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label survivor recovery?. Show all posts
Showing posts with label survivor recovery?. Show all posts

Monday, May 4, 2026

A narrative review of AI-driven stroke rehabilitation systems through the lens of human motor learning

 I can't tell if this got anywhere closer to getting survivors recovered!

A narrative review of AI-driven stroke rehabilitation systems through the lens of human motor learning


  • 1. School of Computer Science, University of Nottingham, Nottingham, United Kingdom

  • 2. School of Psychology, University of Nottingham, Nottingham, United Kingdom

Abstract

Introduction: 

Stroke represents a leading global cause of disability, often causing motor impairments that diminish quality of life. Neurorehabilitation that leverages human motor learning (HML) theories is crucial for post-stroke recovery. Therapists guide repetitive practice that supports re-learning, and they adjust assistance to individual needs and progress. Robot-assisted rehabilitation has advanced this approach, and recent work shows AI-driven systems can improve adaptability to patient behavior beyond earlier technologies. However, notably few systems aim to explicitly replicate therapist assistance from the perspective that physical assistance is a motor skill in itself.


Methodology: 

This narrative review examines advances in AI-driven stroke rehabilitation, analyzing how systems facilitate HML within patients and how their models approximate HML mechanisms. By breaking down the four core HML processes to their essentials, using Marr's tri-level hypothesis, we compare machine learning models used within rehabilitation systems to the HML processes.


Results: 

Many of the reviewed systems appear to primarily facilitate use-dependent and sensory-prediction error-based learning, with limited facilitation of reinforcement learning or strategy-based learning. Explicit modeling of therapist HML within control frameworks appears relatively rare. Implicitly, many of the reviewed AI systems functionally represent one or two HML processes.


Conclusion: 

Current research often considers HML primarily in patients, whereas therapists' own HML likely underpins the robustness and adaptability of clinical assistance. Interpreting the reviewed rehabilitation systems through this lens highlights opportunities for therapist-inspired multi-process controllers, improved benchmarking with clinical scales, longitudinal retention studies, and AI-driven closed-loop neuromodulation to enhance personalization, adaptability, and outcomes, and to support clinical translation into routine practice.

Monday, March 16, 2026

Efficacy of digital health technologies as adjunctive functional training in occupational therapy for stroke rehabilitation: a meta-analysis

 NO efficacy percentages, so completely failed at your research!

Efficacy of digital health technologies as adjunctive functional training in occupational therapy for stroke rehabilitation: a meta-analysis

Review Article Published:14 March 2026Volume 47344 2026Cite this article Save articleNeurological SciencesAims and scopeSubmit manuscript

Abstract

Background

Post-stroke rehabilitation is essential for achieving functional recovery. Using digital health technologies as adjunctive functional training within occupational therapy offers a promising approach to improve training outcomes. However, a comprehensive and updated synthesis of the efficacy of this adjunctive approach is needed.

Methods

Utilizing a systematic search strategy, we identified pertinent randomized controlled trials (RCTs) from eight databases. The emphasis was placed on stroke rehabilitation studies that incorporated both digital health technologies and occupational therapy (search date: May 27, 2025). The primary outcomes assessed included upper limb motor function and activities of daily living, while secondary outcomes encompassed hand function, balance, and cognitive function. Data were synthesized using Stata 18.0, accompanied by subgroup analyses to investigate heterogeneity.

Results

This meta-analysis included 822 stroke survivors from 18 studies. The mean difference (MD) and its 95% confidence interval (CI) were used to assess the between-group comparison at post-intervention. The results showed that adjunctive DHT intervention led to significant improvements compared to controls in upper limb motor function (MD: 6.46; 95%CI [5.29, 7.63]; P < 0.001) and activities of daily living (MD: 9.52; 95%CI [5.63, 13.41]; P < 0.001). Additionally, benefits were noted in hand function and cognitive performance. However, no statistically significant difference was found between the groups for balance function.

Conclusion

Current evidence indicates that digital health technologies, when used as an adjunctive functional training tool alongside occupational therapy, enhance upper limb motor function(NOT GOOD ENOUGH! You incompetently don't know that survivors want 100% recovery? Or you do know and are OK with failure of your survivor requirements! Take your pick: FAILURE OR INCOMPETENCE! No other options exist!)  and activities of daily living for stroke survivors.Additionally, benefits have been noted in hand function and cognitive performance. However, the impact of these technologies on balance function remains inconclusive.

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Friday, April 15, 2022

Should we adjudicate outcomes in stroke trials? A systematic review

No idea what this means in clinical trials. Regardless, what the fuck good did this research do in getting survivors recovered?

Adjudication is the legal process by which an arbiter or judge reviews evidence and argumentation, including legal reasoning set forth by opposing parties

Should we adjudicate outcomes in stroke trials? A systematic review

First Published April 4, 2022 Research Article 

Background: 

Central adjudication of outcomes is common in randomised clinical trials in stroke. The rationale for adjudication is clear; centrally adjudicated outcomes should have less random and systematic errors than outcomes assessed locally by site investigators. However, adjudication brings added complexities to a clinical trial and can be costly.

Aim: 

To assess the evidence for outcome adjudication in stroke trials.

Summary of review: 

We identified twelve studies evaluating central adjudication in stroke trials. The majority of these were secondary analyses of these studies, and the results of all of these would have remained unchanged had central adjudication not taken place, even for trials without sufficient blinding. The largest differences between site-assessed and adjudicator-assessed outcomes were between the most subjective outcomes, such as causality of serious adverse events. We found that the cost of adjudication could be upwards of £100,000 for medium to large prevention trials. These findings suggest that the cost of central adjudication may outweigh the advantages it brings in many cases. However, through simulation, we found that only a small amount of bias is required in site investigators’ outcome assessments before adjudication becomes important.

Conclusions: 

Central adjudication may not be necessary in stroke trials with blinded outcome assessment. However, for open-label studies, central adjudication may be more important.

 

Wednesday, January 13, 2021

Stroke is proud to present the Top 10 most discussed articles published in 2020 using Altmetric Scores.

Notice very specifically that NONE OF THEM are about stroke recovery. The takeaway from that is that Stroke readers don't give a shit about survivor recovery. 

 Stroke is proud to present the Top 10 most discussed articles published in 2020 using Altmetric Scores.

The majority of these listed articles are Original Research, while excluding AHA Scientific Statements. We invite you to peruse the list of these excellent articles, and we congratulate each author team for their innovative research. Altmetrics are used to report how often journal articles are discussed, shared, or mentioned on social or traditional media throughout the world.

Acute Cerebrovascular Events in Hospitalized COVID-19 Patients
Aaron Rothstein, Olivia Oldridge, Hannah Schwennesen, David Do, Brett L. Cucchiara

Smoking Causes Fatal Subarachnoid Hemorrhage: A Case-Control Study of Finnish Twins
Ilari Rautalin, Miikka Korja, Jaakko Kaprio

SARS-CoV-2 and Stroke in a New York Healthcare System
Shadi Yaghi, Koto Ishida, Jose Torres, Brian Mac Grory, Eytan Raz, Kelley Humbert, Nils Henninger, Tushar Trivedi, Kaitlyn Lillemoe, Shazia Alam, Matthew Sanger, Sun Kim, Erica Scher, Seena Dehkharghani, Michael Wachs, Omar Tanweer, Frank Volpicelli, Brian Bosworth, Aaron Lord, Jennifer Frontera

Utility of Apical Lung Assessment on Computed Tomography Angiography as a COVID-19 Screen in Acute Stroke
Charles Esenwa, Ji-Ae Lee, Taha Nisar, Anna Shmukler, Inessa Goldman, Richard Zampolin, Kevin Hsu, Daniel Labovitz, David Altschul, Linda B. Haramati

Hypothetical Lifestyle Strategies in Middle-Aged Women and the Long-Term Risk of Stroke
Priyanka Jain, Claudia K. Suemoto, Kathryn Rexrode, JoAnn E. Manson, James M. Robins, Miguel A. Hernán, Goodarz Danaei

Urban-Rural Inequities in Acute Stroke Care and In-Hospital Mortality
Gmerice Hammond, Alina A. Luke, Lauren Elson, Amytis Towfighi, Karen E. Joynt Maddox

Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Ischemic Stroke
Eduard Valdes Valderrama, Kelley Humbert, Aaron Lord, Jennifer Frontera, Shadi Yaghi

Marijuana Use Among Young Adults (18–44 Years of Age) and Risk of Stroke: A Behavioral Risk Factor Surveillance System Survey Analysis
Tarang Parekh, Sahithi Pemmasani, Rupak Desai

Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke: The Global COVID-19 Stroke Registry
George Ntaios, Patrik Michel, Georgios Georgiopoulos, Yutao Guo, Wencheng Li, Jing Xiong, Patricia Calleja, Fernando Ostos, Guillermo González-Ortega, Blanca Fuentes, María Alonso de Leciñana, Exuperio Díez-Tejedor, Sebastian García-Madrona, Jaime Masjuan, Alicia DeFelipe, Guillaume Turc, Bruno Gonçalves, Valerie Domigo, Gheorghe-Andrei Dan, Roxana Vezeteu, Hanne Christensen, Louisa Marguerite Christensen, Per Meden, Lejla Hajdarevic, Angela Rodriguez-Lopez, Fernando Díaz-Otero, Andrés García-Pastor, Antonio Gil-Nuñez, Errikos Maslias, Davide Strambo, David J. Werring, Arvind Chandratheva, Laura Benjamin, Robert Simister, Richard Perry, Rahma Beyrouti, Pascal Jabbour, Ahmad Sweid, Stavropoula Tjoumakaris, Elisa Cuadrado-Godia, Ana Rodríguez Campello, Jaume Roquer, Tiago Moreira, Michael V. Mazya, Fabio Bandini, Karl Matz, Helle K. Iversen, Alejandra González-Duarte, Cristina Tiu, Julia Ferrari, Milan R. Vosko, Helmut J.F. Salzer, Bernd Lamprecht, Martin W. Dünser, Carlo W. Cereda, Ángel Basilio Corredor Quintero, Eleni Korompoki, Eduardo Soriano-Navarro, Luis Enrique Soto-Ramírez, Paulo F. Castañeda-Méndez, Daniela Bay-Sansores, Antonio Arauz, Vanessa Cano-Nigenda, Espen Saxhaug Kristoffersen, Marjaana Tiainen, Daniel Strbian, Jukka Putaala, Gregory Y.H. Lip

Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults
Reed Mszar, Shiwani Mahajan, Javier Valero-Elizondo, Tamer Yahya, Richa Sharma, Gowtham R. Grandhi, Rohan Khera, Salim S. Virani, Judith Lichtman, Safi U. Khan, Miguel Cainzos-Achirica, Farhaan S. Vahidy, Harlan M. Krumholz, Khurram Nasir

 

Sunday, September 6, 2020

Asymmetrical cortical vein sign predicts early neurological deterioration in acute ischemic stroke patients with severe intracranial arterial stenosis or occlusion

 Under what scenario did you think anything here is going to get survivors recovered? SOLVE STROKE YOU BLITHERING IDIOTS, PREDICTIONS ARE USELESS.  I would fire the lot of you.

Asymmetrical cortical vein sign predicts early neurological deterioration in acute ischemic stroke patients with severe intracranial arterial stenosis or occlusion


Abstract

Background

Susceptibility weighted imaging (SWI) provides an approximate assessment of tissue perfusion and shows prominent hypointense cortical veins in the ischemic territory because of the increased concentration of deoxyhemoglobin. We aimed to evaluate whether asymmetrical prominent cortical vein sign (APCVS) on SWI can predict early neurological deterioration (END) in acute ischemic stroke patients with severe intracranial arterial stenosis or occlusion (SIASO).

Methods

One hundred and nine acute ischemic stroke patients with SIASO who underwent SWI were retrospectively recruited. END was defined as an increase in the National Institutes of Health Stroke Scale score 2 points despite standard treatment in the first 72 h after admission. The APCVS was defined as more and/or large vessels with greater signal loss than those in the opposite hemisphere on SWI.

Results

Thirty out of the 109 (27.5%) patients developed END. Sixty (55.0%) patients presented with APCVS on SWI. APCVS occurred in 24 (80%) patients with END, whereas it only occurred in 36 (45.6%) patients without END (P = 0.001). Patients with APCVS were more likely to have END (40.0%, vs. 12.2%, P = 0.001) than those without END. Multivariate logistic regression indicated that APCVS (OR = 4.349, 95% C.I. = 1.580–11.970, P = 0.004) was a significant predictor of END in acute ischemic stroke patients with SIASO, adjusted for previous stroke history and acute infarct volume.

Conclusions

In acute ischemic stroke patients with SIASO, the APCVS might be a useful neuroimaging marker for predicting END, which suggests the importance of evaluation of perfusion status.

 

Wednesday, February 5, 2020

Review Article Lower-Limb Robotic Rehabilitation: Literature Review and Challenges

So absolutely nothing useful came from this review. NOTHING that will get survivors recovered. Useless. 

Review Article Lower-Limb Robotic Rehabilitation: Literature Review and Challenges


I˜naki D´ıaz, Jorge Juan Gil, and Emilio S´anchez
 Applied Mechanics Department, CEIT, Paseo Manuel Lardiz ´abal 15, 20018 San Sebasti´an, Spain
Correspondence should be addressed to I˜naki D´ıaz, idiaz@ceit.esReceived 20 April 2011; Revised 11 August 2011; Accepted 5 September 2011Academic Editor: Doyoung JeonCopyright © 2011 I˜naki D´ıaz et al. This is an open access article distributed under the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This paper presents a survey of existing robotic systems for lower-limb rehabilitation. It is a general assumption that robotics will play an important role in therapy activities within rehabilitation treatment. In the last decade, the interest in the field has grown exponentially mainly due to the initial success of the early systems and the growing demand caused by increasing numbers of stroke patients and their associate rehabilitation costs. As a result, robot therapy systems have been developed worldwide for training of both the upper and lower extremities. This work reviews all current robotic systems to date for lower-limb rehabilitation, as well as main clinical tests performed with them, with the aim of showing a clear starting point in the field. It also remarks some challenges that current systems still have to meet in order to obtain a broad clinical and market acceptance.