Would this work on CPSP(Central post-stroke pain)?
Central post-stroke pain (CPSP) is a neuropathic pain syndrome that can occur after a cerebrovascular accident.
If your doctor does nothing, no initiation of research, you don't have a functioning stroke doctor! Over a decade of incompetence! WOW!
CPSP (22 posts to December 2011)
Repetitive High Concentration Capsaicin Patch Applications Effective for Nerve Pain in a Real-World Setting
Real-world use of a high concentration capsaicin patch (HCCP) reduced pain intensity and concomitant opioid use in patients with neuropathic pain, according to a study published in Pain Practice.
“Consistent with the progressive response seen in prospective clinical trials involving repeated use of topical capsaicin, our research indicates that patients
The researchers analysed data from 97 patients who received at least 2 HCCP treatments between January 2011 and July 2022 at an outpatient pain centre in Wiesbaden. Patients were receiving treatment due to neuropathic back pain, postoperative or post-traumatic neuropathic pain, or postherpetic neuralgia.
On average, patients were 1.7 years on HCCP treatment, received 5.9 repeated treatments, and 1.2 patches per application. Average time between applications was 3 months. The majority of patients received concomitant medications, with opioids, anticonvulsants, and antidepressants being the most common.
The average morphine equivalent daily dose was 88 mg at the beginning of HCCP treatment and was significantly (P = .0446) reduced by 5 mg when comparing with the average daily dose received within 2 years (83 mg). The average daily dose increased in 13 patients, decreased in 21 patients, and remained constant within the HCCP treatment in 18 patients.
Reduction in the average daily dose of morphine equivalent was higher in patients with at least 3 applications (-6.8 mg) compared with patients who received exactly two applications (-3.1 mg).
“Our results demonstrate that two-thirds of patients treated with at least 2 HCCP applications experienced an improvement in pain intensity,” the authors wrote. “This finding underscores the potential benefits of HCCP as an effective treatment modality for pain relief. Importantly, the proportion of patients experiencing a significant improvement in pain intensity was substantially higher among those who received at least 3 applications compared with those with exactly 2 applications, suggesting an increase in response with multiple HCCP application.”
The authors stated that further research and larger-scale studies are warranted to validate the results of their study and elucidate the optimal treatment protocols for maximising the benefits of HCCP in pain management.
Reference: https://onlinelibrary.wiley.com/doi/10.1111/papr.13345
SOURCE: Wiley
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