Deans' stroke musings: Associations of the ‘weekend warrior’ physical activity pattern with mild dementia: findings from the Mexico City Prospective Study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, November 5, 2024

Associations of the ‘weekend warrior’ physical activity pattern with mild dementia: findings from the Mexico City Prospective Study

Just maybe you'd like something more specific since weekend warrior has no basis in factual measurements.

This one suggests 8900 steps a day:

Can Exercise Protect Against Alzheimer's?

The latest here:

Associations of the ‘weekend warrior’ physical activity pattern with mild dementia: findings from the Mexico City Prospective Study

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Supplementary
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Original research

Associations of the ‘weekend warrior’ physical activity pattern with mild dementia: findings from the Mexico City Prospective Study

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http://orcid.org/0000-0001-6748-6218Gary O'Donovan1,
http://orcid.org/0000-0002-4384-4962Fanny Petermann-Rocha2,3,
http://orcid.org/0000-0003-3177-6576Gerson Ferrari4,5,
http://orcid.org/0000-0002-0538-0650Catalina Medina6,
http://orcid.org/0000-0001-8048-9165Carolina Ochoa-Rosales7,8,
http://orcid.org/0000-0002-9190-3568Olga L L Sarmiento1,
http://orcid.org/0000-0001-6758-5101Agustín Ibáñez7,9,10

Correspondence to Dr Gary O'Donovan; g.odonovan@uniandes.edu.co

Abstract

Objectives To investigate associations of the ‘weekend warrior’ physical activity pattern with mild dementia.

Methods Participants in the Mexico City Prospective Study were surveyed from 1998 to 2004 and re-surveyed from 2015 to 2019. Participants were asked about leisure time physical activity at baseline. Those who exercised up to once or twice per week were termed ‘weekend warriors’ and those who exercised more often were termed ‘regularly active’. A Mini Mental State Examination (MMSE) was used to assess mild dementia at re-survey. Cox models were adjusted for age, sex, education, income, blood pressure, smoking, body mass index, civil status, sleep, diet and alcohol at baseline. The attributable fraction was defined as the proportion of cases that would not exist if all adults were to exercise once or twice per week or more often.

Results The analysis included 10 033 adults of mean (SD) age 51 (10) years followed for 16 (2) years. There were 2400 cases when mild dementia was defined as a score of ≤22 on the MMSE. Compared with the group that reported no sport or exercise, the hazard ratio was 0.75 (95% CI 0.61 to 0.91) in the weekend warrior group, 0.89 (95% CI 0.78 to 1.02) in the regularly active group and 0.84 (95% CI 0.75 to 0.95) in the combined group. The attributable fraction was 13% (95% CI 5% to 21%). Similar results were observed when mild dementia was defined as a score of ≤23 on the MMSE.

Conclusions This longitudinal analysis suggests that the weekend warrior physical activity pattern is associated with a reduced risk of mild dementia.

Data availability statement

Data are available upon reasonable request. Mexico City Prospective Study data are available for open-access data requests. The data access policy is described online: http://www.ctsu.ox.ac.uk/research/mcps.

https://doi.org/10.1136/bjsports-2024-108460