Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label tipping point. Show all posts
Showing posts with label tipping point. Show all posts

Wednesday, November 9, 2022

Reaching a Tipping Point for Neurorehabilitation Research: Obstacles and Opportunities in Trial Design, Description, and Pooled Analysis

 Until we get the correct research objective for all stroke research, we will never solve stroke. The major obstacle is we have NO strategy to solve stroke and NO leadership to drive that strategy to completion. It is that fucking simple.

1. All stroke research leads to 100% recovery.

2. All stroke research creates rehab protocols usable and understandable by survivors.

Reaching a Tipping Point for Neurorehabilitation Research: Obstacles and Opportunities in Trial Design, Description, and Pooled Analysis

The record-breaking pace of COVID-19 vaccine development and implementation depended heavily on collaboration among academic, government, and commercial stakeholders, especially through data-sharing and robust multicenter trials. Collaborative efforts have not been as fruitful in fields such as neurorehabilitation, where non-pharmacological interventions play a much larger role. Barriers to translating scientific advancements into clinical practice in neurorehabilitation include pervasively small study sizes, exacerbated by limited funding for non-pharmacological multicenter clinical trials; difficulty standardizing—and adequately describing—non-pharmacological interventions; and a lack of incentives for individual patient-level data-sharing. These barriers prevent reliable meta-analysis of non-pharmacological clinical studies in neurorehabilitation. This point-of-view will highlight these challenges as well as suggest practical steps that may be taken to improve the neurorehabilitation pipeline between evidence and implementation.

Get full access to this article

Saturday, July 17, 2021

All at once vs. chronic by Seth Godin applied to stroke

 Stroke is chronic and has totally been overtaken by dementia/Alzheimers. Stroke needs to get to the tipping point  where every piece of research is breathlessly reported on. But that won't occur with current stroke leadership who in some la-la land think nothing needs to be done for stroke, it's already solved.

The whole problem is the stroke world thinks nothing needs to be done as proven by this meme on World Stroke Day a few years ago. Whomever approved that is a complete blithering idiot.

What a lying piece of shit

All at once vs. chronic by Seth Godin applied to stroke 

The emergency wins every time.

The newspaper, social media, dinner time conversation, the principal’s office, sportscasters, the weather, the boardroom–the conversation is almost always about the emergency of the moment. The thing that’s happening all at once.

We have a volunteer fire department in town, but we don’t often have a volunteer corps dedicated to long-term culture change. Even typing that out seems odd.

But the chronic problems define our future, and the persistent changes over time brought us to where we are. Evolution of species is a chronic process. And most of us die from chronic illnesses.

What would it take for us to spend even a fraction of our time and energy and attention on the chronic instead of the urgent? Drip by drip.

 

Sunday, June 9, 2019

Rat brains provide even more evidence our brains operate near tipping point

You can try to understand this or just turn it over to your doctor to explain. You need to know how close you are to a 'tipping point' after your stroke damage and how to prevent that. 

Rat brains provide even more evidence our brains operate near tipping point

"Avalanches" in electrical activity between neurons provide a telltale signature.





A real human brain suspended in liquid within a human silhouette carved into acrylic, on display at the Bristol Science Centre in England. New research finds more evidence that the brain operates near a critical point.
Enlarge / A real human brain suspended in liquid within a human silhouette carved into acrylic, on display at the Bristol Science Centre in England. New research finds more evidence that the brain operates near a critical point.
Ben Birchall/PA Images/Getty Images
The human brain doesn't seem like it would have much in common with how water freezes into ice or heats up into a gas. But over the last decade, evidence has been mounting that the brain as a system functions much like water approaching the critical point of a phase transition. Now a team of Brazilian scientists has found additional evidence in rat brains that this might indeed be the case. The team described its findings in a recent paper in Physical Review Letters.
The notion of so-called "self-organized criticality" dates back to a landmark paper in 1987, when the late Danish physicist Per Bak concluded that nature's exquisite order was the result of a kind of phase transition. That precise moment of transition is colloquially known as the "tipping point" or "critical point."

A brain's the thing

Typically, a classical phase transition only occurs when the temperature and pressure are just right for a given system. Self-organized criticality emerges spontaneously as the result of many local interactions between the many elements of a system, like millions of grains of sand running from the top to the bottom of an hourglass. The pile grows, grain by grain, until it becomes sufficiently unstable that the next grain to drop makes the pile collapse in an avalanche. The base of the pile widens, restoring stability, and the pile-up begins anew, until the sand pile hits the critical point again. Those avalanches follow a so-called "power law," meaning smaller ones happen more often than larger ones.
Bak extended his ideas in a 1996 book, How Nature Works, applying the notion of self-organized criticality to earthquakes, financial markets, traffic jams, biological evolution, how galaxies are distributed in the universe, and the brain. In fact, he annoyed a group of neuroscientists in 1999 when he blithely informed them that he had figured out the fundamental principles behind how the brain works. Much like the pile of sand in an hourglass, he proposed that the brain teeters at that same critical point, a balance achieved by avalanches of electrical activity between neurons at all size scales. In other words, he proposed that electrical activity should follow a power law. The idea is that this critical state is a kind of "Goldilocks zone" that optimizes the transfer and processing of information in the brain while still maintaining stability.


The Bak–Tang–Wiesenfeld (Abelian) sandpile, here composed of 28 million grains, is a famous model for self-organized criticality.
Enlarge / The Bak–Tang–Wiesenfeld (Abelian) sandpile, here composed of 28 million grains, is a famous model for self-organized criticality.
Granted, the brain is not a highly idealized model sandpile, but the concept makes a certain degree of sense. The brain is a complex system that must adapt to constantly changing circumstances, so why shouldn't it have evolved mechanisms to maintain an ideal balance between order and disorder, so to speak? "A brain that is not critical is a brain that does exactly the same thing every minute, or, in the other extreme, is so chaotic that it does a completely random thing, no matter what the circumstances," Dante Chialvo, a neurophysiologist with UCLA and the National Scientific and Technical Research Council in Argentina, memorably told Quanta in 2014. "That is the brain of an idiot."

Signifying nothing?

All this was purely theoretical—and quite controversial—until 1992, when Swedish scientists conducted experiments with grains of rice pressed between glass plates, adding grains one by one and recording the eventual avalanches on camera. As Bak had predicted, there were more smaller avalanches than larger ones, following the telltale power law. In 2003, Indiana University biophysicist John Beggs and several colleagues were the first to demonstrate that slices of a brain's cortex showed evidence of an exponent relation. Add in evidence gleaned from other studies using magnetoencephalography, electroencephalography (EEG) recordings of the interactions between individual neurons, and computer simulations with fMRI imaging data of the brain's resting state, and it starts to look like proponents of the "brains at the tipping point" hypothesis might just have a case.
The biggest issue is what one might call a "fine-tuning" problem: critical states in nature are generally fragile, in that a slight perturbation will move it away from the exact critical point. And the brain is an especially noisy system, so there would be many such perturbations. That's why Beggs and his Indiana University colleague Gerardo Ortiz have since argued that perhaps the brain hovers near, rather than precisely at, the critical point—think of it as more of a "quasi critical" phase space than a traditional tipping point. Similarly, Viola Priesemann of the Max Planck Institute for Dynamics and Self-Organization in Gottingen has argued that the brain operates in a slightly subcritical zone.
Not everyone is convinced. Among the most vocal critics of the brain operating in a critical state is Alain Destexhe, a theoretical neuroscientist at the National Center for Scientific Research (CNRS) in France. Among other concerns, power law distribution isn't sufficient evidence for criticality, since other processes in nature can mimic that signature. In a 2017 paper, he and co-author Jonathan Touboul proposed that the real sign of criticality would be the critical exponent relation.


Signatures of criticality as a function of cortical spiking variability across several different species.
Enlarge / Signatures of criticality as a function of cortical spiking variability across several different species.
A.J. Fontenele et al./PRL

"This is mind-blowing"

Furthermore, if the brain operates near criticality, what kind of phase transition might be taking place? That's the question Antonio Fontenele and Mauro Copelli—both of the Universidade Federal de Pernambuco in Brazil—and various colleagues sought to answer with their experiments. They monitored the brains of lab rats as the rats moved from being asleep (thanks to a bit of anesthesia) and awake—technically, synchronized and unsynchronized states, respectively—and concluded that the rodent brains showed all the hallmarks of moving through a critical state as they cycled between sleep and wakefulness. Specifically, researchers saw spiking avalanches following a power distribution.
In other words, "The transition is between unsynchronized and synchronized firing, this transition point is indeed critical, and the brain hovers around it," said Beggs, who was not involved with the experiments. "They had avalanches, too, and they satisfied the exponent relation. To me, this is mind-blowing."
Beggs was especially impressed with the second figure in this latest paper, which showed every data point following the exponent relation—stronger evidence for criticality than a power law distribution alone. That figure includes data from multiple experiments involving anesthetized rats, freely moving mice, anesthetized macaque monkeys, and even turtle brains. That's in keeping with a paper last year reporting on the recording neuronal activity in the brains of zebrafish, which showed similar evidence of hovering near criticality.
"This shows that a variety of quite different species, under different conditions, all line up near the critical point," said Beggs. "Usually with biological data you expect a cloud of points that may show some rough correlation. Here you get something noticeably different: there is order. This suggests that different brains are hovering around criticality, independent of many biological details." This should delight physicists, who love universality—that is, when an equation can capture the large-scale behavior of a complicated system like the brain—and irritate biologists. However, "It is very difficult to dismiss the idea of criticality in the cortex, given the data points lining up pretty nicely across species," said Beggs.
DOI: Physical Review Letters, 2019. 10.1103/PhysRevLett.122.208101  (About DOIs).

Wednesday, January 2, 2019

Is the Rising Storm of Alzheimer's Disease Stoppable?

You can read and weep about this at the link. But I'm focusing on the complete failure of our stroke associations to reach this same tipping point on stroke. Now 1 in 4 will have a stroke and nothing exists for effective stroke rehab protocols to 100% recover. So 10 million yearly stroke survivors  are fucked but the meme from World Stroke day is keep your head firmly buried up your ass so you can't see all the problems in stroke.  

What a bald faced lie

Is the Rising Storm of Alzheimer's Disease Stoppable?

Saturday, September 22, 2018

Alzheimer's Disease Burden to Double by 2060

At 800,000 strokes a year in the US by 2060 that means we will have 33.6 million stroke cases, and that is a low estimate as our country ages.  If our fucking failures of stroke associations can't figure out how to get stroke to the tipping point where tons of research is directed to stroke and every research is reported by all media they need to be dissolved and run by survivors. But never mind, stroke is treatable per the meme from World Stroke Day a couple of years ago.  That has got to be the biggest lying piece of shit stroke associations have ever put out.





Alzheimer's Disease Burden to Double by 2060


Nearly 14 million Americans may have Alzheimer's disease by then

  • by Contributing Writer, MedPage Today
Over 3% of the population -- nearly 14 million Americans -- may have Alzheimer's disease or related dementias by 2060, according to a new CDC report.
The burden of Alzheimer's disease and related dementias, which was 1.6% of the U.S. population in 2014, is projected to double to 3.3% by 2060, reported the CDC's Kevin Matthews, PhD, and and colleagues in Alzheimer's & Dementia.
That translates to a jump from 5 million to 13.9 million Americans affected by the disease.
Hispanic Americans are expected to have the biggest increase due to population growth, but non-Hispanic whites still will have the most Alzheimer's cases, based on population numbers.
The study is the first to forecast Alzheimer's disease by race and ethnicity. It shows "that as the U.S. population increases, the number of people affected by Alzheimer's disease and related dementias will rise, especially among minority populations," CDC Director Robert Redfield, MD, said in a statement.
Currently, Alzheimer's disease is the fifth leading cause of death of Americans age 65 and older, the CDC said. Of people in that age group, African Americans have the highest prevalence of Alzheimer's disease and related dementias at 13.8%, followed by Hispanics at 12.2%, non-Hispanic whites at 10.3%, American Indian and Alaska Natives at 9.1%, and Asian and Pacific Islanders at 8.4%.
By 2060, 3.2 million Hispanics and 2.2 million African Americans are expected to have Alzheimer's disease and related dementias, due in part to longer life spans.
The report also addressed the need to support caregivers of Alzheimer's and dementia patients and the importance of early diagnosis. "Early diagnosis is key to helping people and their families cope with loss of memory, navigate the health care system, and plan for their care in the future," Redfield said.
CDC researchers used population projections from the U.S. Census Bureau and percentages of Medicare fee-for-service beneficiaries 65 and older with Alzheimer's disease and related dementias from the Centers for Medicare & Medicaid Services to estimate the number of people with Alzheimer's by age, sex, race, and ethnicity in 2014 and 2060.
The findings and conclusions in the study do not necessarily represent the official positions of the Centers for Disease Control and Prevention or the Centers for Medicare and Medicaid Services.
last updated

Tuesday, January 24, 2017

Alzheimer’s: Every Minute Counts

What should be occurring with stroke if it had hit the tipping point where all news about stroke is breathlessly reported. Failure on a massive scale from our stroke associations.
Someone in the United States has a stroke every 40 seconds, more often than Alzheimers yet no reporting is done on that because our fucking failures of stroke associations seem to only put out 'happy talk'.
https://danablog.org/2017/01/24/alzheimers-every-minute-counts/
In the United States, someone is diagnosed with Alzheimer’s disease every minute; around the world, it’s every four seconds. “It is the biggest epidemic we have in this country,” says Harvard University’s Rudolph Tanzi, “I’m shocked that people aren’t panicked about what this disease is going to do to the country or to their families.”
This Wednesday (January 25) at 10 pm ET, PBS is premiering “Alzheimer’s: Every Minute Counts,” an urgent wake-up call about the national threat posed by the disease. The documentary includes interviews with doctors, caregivers, and longtime researchers of the disease, such as Dana Alliance member Tanzi.
With the number of people finding they have Alzheimer’s rapidly escalating as the baby boom generation reaches 65 and older, researchers estimate that by 2050, the rate of diagnosis won’t be every minute but every 33 seconds. Scientists and drug-makers have yet to find a cure; they cite a dire need of federal funding for further research. No lifestyle activity is guaranteed to prevent the disease, Tanzi says, but there are measures we can take, based on various epidemiology studies and trials, that can reduce risk.
Among those things, he recommends:
  1. Stay active. Exercise, which can help remove the pathology and stop inflammation (considered by many a key part of Alzheimer’s disease).
  2. Get enough sleep. Scientists have found that during the deepest part of sleep (slow-wave sleep) is the only time the brain doesn’t make the amyloid proteins responsible for creating the plaques associated with the disease. Tanzi recommends a minimum of seven to eight hours a night to ensure the brain has time to “clean itself.”
  3. Adopt a healthy diet. The Mediterranean diet has shown to be most effective in reducing risk; it includes more fiber, olive oil, fruits, nuts, more fish, vegetables, and less red meat.
  4. “Keep moving” physically, socially, and intellectually. Every time you learn something new, your brain creates new connections between synapses and strengthens the ones already there. In Alzheimer’s, what correlates most with the degree of dementia is loss of synapses.
To watch the full, four-minute video of Tanzi’s tips on keeping our brains as healthy as possible, click here.

Friday, January 6, 2017

Top 20 Neuroscience News Articles of 2016

I guess stroke has absolutely no importance in neuroscience news. I blame our fucking failures of stroke associations not getting stroke to the tipping point where every stroke news article is awaited with breathless anticipation.  All because they just do the 'happy talk', never discussing all the fucking problems in stroke.
http://neurosciencenews.com/top-2016-neuroscience-articles-5842/

We have selected these articles based on stories that received the most views from our readers, as well as the most shares and likes from Reddit, Facebook, Twitter, Google+ and our other social networks.
This list is based on popularity among Neuroscience News audiences and is not based on importance of research directly.
Thanks to all of our readers and social media fans for reading and sharing our news throughout 2016.
In no particular order, here are some of the most popular Neuroscience News articles of 2016.
Happy New Year!

Depression Is Not Just a Mental Illness, It Affects the Whole Organism
1 – Depression Is Not Just a Mental Illness, It Affects the Whole Organism

Read the full article.

Researchers Identify Virus and Two Types of Bacteria as Major Causes of Alzheimer’s
2 – Researchers Identify Virus and Two Types of Bacteria as Major Causes of Alzheimer’s
.Read the full article.

Chronic Fatigue Syndrome Is Not in Your Head, It’s in Your Gut
3 – Chronic Fatigue Syndrome Is Not in Your Head, It’s in Your Gut

Read the full article.

Heavy Cannabis Use Associated With Reduced Dopamine Release
4 – Heavy Cannabis Use Associated With Reduced Dopamine Release

Read the full article.

Cognitive Offloading: How the Internet is Increasingly Taking Over Human Memory
5 – Cognitive Offloading: How the Internet is Increasingly Taking Over Human Memory

Read the full article.

Human Behavior Study Identifies Four Basic Personality Types
6 – Human Behavior Study Identifies Four Basic Personality Types

Read the full article.

Head Impacts Lead to Brain Changes in High School Football Players
7 – Head Impacts Lead to Brain Changes in High School Football Players

Read the full article.

This is Your Brain on LSD
8 – This is Your Brain on LSD

Read the full article.

Eating Fish While Pregnant Improves Baby’s Brain Development
9 – Eating Fish While Pregnant Improves Baby’s Brain Development

Read the full article.

Dietary Supplement May Prevent and Reverse Damage to Aging Brain
10 – Dietary Supplement May Prevent and Reverse Damage to Aging Brain

Read the full article.

Manipulation of Specific Neurons Helps to Erase Bad Memories and Enhance Good Ones
11 – Manipulation of Specific Neurons Helps to Erase Bad Memories and Enhance Good Ones

Read the full article.

Single Species of Gut Bacteria Can Reverse Autism Related Social Behavior: Mouse Study
12 – Single Species of Gut Bacteria Can Reverse Autism Related Social Behavior: Mouse Study

Read the full article.

Rhythm of Breathing Affects Memory and Fear
13 – Rhythm of Breathing Affects Memory and Fear
Perhaps our top story of the year was published in early December and comes from a team of researchers from Northwestern University.
Researchers have been able to link breathing rhythm to emotional judgement and enhanced memory recall.
There is a ‘dramatic difference’ in neural activity in both the hippocampus and amygdala depending on whether you are inhaling or exhaling, the researchers report. This can affect how you perceive stimuli and your ability to recall memories.
Read the full article.

How LSD Affects Language
14 – How LSD Affects Language
During 2016, we seemed to report fairly often on the neurobiological effects of LSD. Back in August, a new study was released that looked at the effect LSD had on language processing and skills.
Researchers reported that, when people under the influence of LSD were asked to name specific objects, their reaction times did not change, but they were more likely to mistakenly call objects by different names. For example, when presented with an image of a car, people who had taken LSD would instead name the stimuli as a ‘bus’ or other vehicle.
Based on their findings, the researchers believe that LSD could allow ‘quicker access to far away concepts stored in the brain’ (Neiloufar Family) and could help in the treatment of psychiatric illnesses.
Read the full article.

Broca and Wernicke Are Dead – It’s Time to Rewrite the Neurobiology of Language
15 – Broca and Wernicke Are Dead – It’s Time to Rewrite the Neurobiology of Language
One of the most influential news stories of the year was released in early November and could have implications for the way researchers consider the neurological basis of language function.
A new paper published by the BPS argued that the ‘Classic Model’ of language function in the brain is obsolete and the continued use could be hampering progress when it comes to researching language production. The researchers call for a new approach that considers how much of language function is overlaid on the cognitive system.
Read the full article.

Brain Structure That Tracks Negative Events Backfires in Depression
16 – Brain Structure That Tracks Negative Events Backfires in Depression
Back in May, we reported on a significant new finding which relates to the neurobiology of depression.
Researchers from University College London discovered people with depression had hyperactive habenula function. Surprisingly, when faced with an adverse event, habenula activity decreased in depressed people. The findings suggest that this brain area functions in a much different way in people with this psychiatric condition.
Read the full article.


How Neurons Talk to Each Other
17 – How Neurons Talk to Each Other
While not so much of a breaking news story, one of our most popular articles of the year provided a comprehensive breakdown of the process of neurotransmission. The article received a great deal of attention via our social network accounts and became quite a hit with educational communities and groups online.
Read the full article.

Our Brains Have a Basic Algorithm That Enables Our Intelligence
18 – Our Brains Have a Basic Algorithm That Enables Our Intelligence
Back in November, we reported on a groundbreaking piece of research that demonstrated our complex brain computations and intelligence are reliant upon a fairly basic algorithm. However, the researcher noted exceptions to the math rule in areas such as the reward system.
Read the full article.

Religious Beliefs Activate Neural Reward Circuits in Same Way As Sex and Drugs
19 – Religious Beliefs Activate Neural Reward Circuits in Same Way As Sex and Drugs
One of our favorite stories of the year was published back in late November and came to us from researchers at the University Of Utah School Of Medicine.
A new neurotheology study looked at the neural networks that are involved in feelings of spirituality.
Through neuroimaging technology, researchers identified activation in the nucleus accumbens, an area of the brain associated with reward, when powerful spiritual feelings are encountered. Interestingly, similar brain activation occurs when people are exposed to pleasurable stimuli such as sex, drugs, music and gambling.
Read the full article.

How the Hippocampus Influences Future Thinking
20 – How the Hippocampus Influences Future Thinking
To conclude our review of the top NeuroscienceNews stories to hit our pages in 2016, we’ll take you back to a fairly recent article.

Monday, October 24, 2016

Women are almost twice as likely to die from a stroke as from breast cancer

But you as the National Stroke Association are doing fucking nothing to solve that problem. Lazy AWARENESS press releases. You haven't figured out how to get stroke to the tipping point where every research paper on stroke is held in breathless anticipation. You don't deserve any money for your useless work. 

Women are almost twice as likely to die from a stroke as from breast cancer


View this message on our website.
Dear dean,
Know the stats...
  • Women are almost twice as likely to die from a stroke as from breast cancer
  • Stroke is the fifth leading cause of death in the U.S.
  • 800,000 people will experience a stroke this year and live to join the 7 million stroke survivors in the U.S.
  • Stroke is a leading cause of serious, long-term disability
  • Strokes in children, teens, and young adults are increasing at an alarming rate
For 32 years, we’ve been committed to raising stroke awareness. Stroke is a sudden and shocking loss for millions of families. But, with your help, we know we can do more to empower our community to understand their risk for stroke and make lifesaving changes.

Please stand with us today by making a gift. Together, we will take the next step in moving the needle forward for stroke survivors and their families.
Thank you again for your continued support; it means so much!
With thanks,
Crystal Blaylock's signature
Crystal Blaylock
Director of Development
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Friday, October 14, 2016

WHO's Director-General candidates: visions and priorities

No reference in here to tackling anything about stroke  which affects 15 million persons a year, 5 million die. The ASA, NSA and WSO can congratulate themselves that they have convinced the whole world that stroke is being treated so well that nothing needs to be done to improve stroke treatment. Stroke has not hit the tipping point where everyone in the world knows about all the fucking problems in stroke and waits breathlessly for advances in stroke results. So the presidents of the ASA, NSA and WSO are not concerned about having a stroke since they will be treated F.A.S.T. and fully recover. Excuse me while I scrape myself off the floor for telling such a whopper of a lie.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2816%2931847-5/fulltext

Friday, June 3, 2016

Stroke Hospitalization Down for Many in U.S.

'Happy talk' like this is preventing anyone from tackling all the fucking problems in stroke. We need gloom and doom reports if we ever expect to get to the tipping point in stroke and have foundations willing to throw money at the stroke problem. A great stroke leader would be pointing to the strategy that still needs to be executed to solve all the problems in stroke.
http://demo.healthday.com/cardiovascular-health-information-20/heart-stroke-related-stroke-353/u-s-stroke-hospitalization-down-for-most-710907.html

But higher rates reported for younger adults, blacks

By
HealthDay Reporter
WEDNESDAY, May 11, 2016 (HealthDay News) -- While Americans suffered fewer strokes overall from 2000 to 2010, stroke rates climbed substantially among younger adults and blacks, a new study found.
Hospitalizations for strokes caused by artery blockages dropped 18.4 percent overall during the decade, with greater decreases among the elderly, University of Southern California researchers found.
Within the overall decrease, however, some groups saw an increase in hospitalizations as the burden of stroke shifted to younger adults. For example, although stroke hospitalizations dropped 50 percent for people 65 and older, they increased nearly 49 percent among 25- to 64 year-olds.
Stroke hospitalizations also varied by race -- up almost 14 percent among blacks.
Dr. Paul Wright, chair of neurology at North Shore University Hospital, in Manhasset, N.Y., said, "There are things we can do to help prevent strokes." Topping the list: living a healthier lifestyle, which can prevent as many as 80 percent of strokes, said Wright, who was not involved with the study.
The study authors said better control of blood pressure, blood sugar and cholesterol probably accounted for the steep decline in strokes among the elderly.
Exactly why strokes are up among younger adults isn't clear, but more awareness of stroke symptoms is the most likely reason, Wright said.
"People are more aware of the risk factors for stroke and seek help when something happens, as opposed to saying, 'I'm getting a little numbness and tingling and weakness, but it will go away,' " he said. "So people are more likely to get help sooner."
Wright believes the higher stroke rate among blacks is largely due to lack of access to care. He also cited a need for more stroke education targeted to this population.
Dr. Amytis Towfighi, senior researcher on the study, emphasized the protective role of lifestyle behaviors in stroke prevention.
"The majority of cardiovascular events including heart attacks and stroke can be prevented through changing seven modifiable risk factors, namely: smoking, obesity, physical inactivity, poor diet, cholesterol, blood pressure and blood sugar," she said.
If you've had a stroke, "it's not too late to change your lifestyle. By making immediate changes one is on the road to a longer, healthier life," said Towfighi, an assistant professor of neurology at USC's Keck School of Medicine.
Healthier lifestyle habits probably accounted for the hefty decline in strokes for seniors -- down 28 percent for those 65 to 84, and more than 22 percent for those 85 and older, Towfighi said.
For the study, Towfighi and her colleagues analyzed data from a national database that collects information on about 8 million hospital stays each year.
They looked at the most common type of stroke, called ischemic stroke. This occurs when a clot in a blood vessel in the brain cuts off the blood supply to that area. Symptoms usually include weakness or numbness and tingling on one side of the body.
The researchers found that stroke hospitalization for whites declined about 12 percent and for Hispanics nearly 22 percent. But it rose 13.7 percent among blacks.
Overall, women saw a steeper decline in stroke than men -- more than 22 percent versus roughly 18 percent.
The study findings were published online May 11 in the Journal of the American Heart Association.
More information
For more about stroke, visit the American Stroke Association.
SOURCES: Amytis Towfighi, M.D. assistant professor, neurology, Keck School of Medicine, University of Southern California, Los Angeles; Paul Wright, M.D., chair, neurology, North Shore University Hospital, Manhasset, N.Y.; May 11, 2016, Journal of the American Heart Association, online

Monday, May 23, 2016

May is Stroke Awareness Month | Learn About Stroke Symptoms and Treatment

This graphic is fucking appalling, only happy and useless information provided. What the graphic should say:

Have a stroke: you're fucking screwed.
tPA only fully works 12% of the time.
Only 10% of survivors almost fully recover.
No cure for spasticity.
No cure for fatigue.
No therapy to prevent dementia.
No publicly available rehab protocols.

Now that would get your attention and likely create a hue and cry to solve stroke and create strokes' tipping point. 

Thursday, April 28, 2016

National Stroke Association - Where the money goes

This in a nutshell points out the whole problem with our stroke associations. Awareness NOT finding solutions to all the problems in stroke. This is so simple to solve;
1. Create and follow a stroke strategy to solve stroke problems. BHAGs (Big Hairy Audacious Goals)  Like repeatable neuroplasticity, repeatable neurogenesis, fatigue, spasticity, aphasia. And since we have no National Stroke Plan or strategy nothing will get done in stroke from the NSA that actually helps survivors.
2. Put out RFPs(Request for Proposals) to researchers to solve those problems.
3. Apply for grant money to fund those research projects.
4. Broadcast the success stories to generate enthusiasm and more foundations that want to get on a successful stroke strategy train. Hit the tipping point for stroke so each stroke success is met with breathless anticipation and media stories.
http://www.stroke.org/

Where the Money Goes


Total Expenses: $3,339,663

  • Administrative: $313,110 - 9%
  • Fundraising: $515,266 - 15%
  • Stroke Education: $2,511,287 - 74%

pie chart

Thursday, April 7, 2016

Cause Celeb: Actor David Hyde Pierce testifies on Alzheimer’s disease

Why can't our fucking failures of stroke associations find a popular actor/actress who had a stroke and use that to show what still needs to be done to solve all the problems in stroke?  We don't need another awareness campaign. We could finally get stroke to the tipping point where every research breakthrough is announced with breathless anticipation. This is so simple that any decent marketer should have thought of this years ago.

Cause Celeb: Actor David Hyde Pierce testifies on Alzheimer’s disease 


Sunday, December 20, 2015

Cardiovascular disease is the top killer in the US - with heart disease and stroke responsible for 1 in 3 deaths

And yet our fucking failures of stroke associations haven't managed to make stroke and cardiovascular disease into a tipping point where every new research item is breathlessly reported on by the popular media. They do lots of press releases but haven't figured out how to make stroke and CVD important.  And this comes from a UK site.
http://www.dailymail.co.uk/health/article-3366388/Cardiovascular-disease-killer-heart-disease-stroke-responsible-1-3-deaths.html 
Cardiovascular disease is the leading cause of death in the US, a new report revealed.
One in every three deaths in the US occurs because of heart disease, stroke and other cardiovascular diseases.
And across the globe, heart disease and stroke are the leading causes of death, according to the American Heart Association.
The AHA’s 2016 Heart Disease and Stroke Statistics Update showed cardiovascular diseases claimed 801,000 lives in the US in 2013 – the last available data.
Of that group, heart disease killed more than 370,000 people.
Stroke took the lives of nearly 129,000 people.
A report from the American Heart Association revealed that cardiovascular disease is the top killer in the US. Heart disease and stroke were also found to be the top two killers worldwide
Dr Mark Creager, president of the AHA, said: ‘Statistics about cardiovascular disease and stroke, and particularly the metrics about death and the factors that contribute to cardiovascular disease are incredibly important.’
The report has been produced annually since 1958.
It uses the most-recent data available from the AHA, the National Institutes of Health, the Centers for Disease Control and Prevention and other government sources.
The statistics help the AHA track the effectiveness of its efforts.
But despite the progress in reducing the number of deaths from heart disease and stroke, Dr Creager said the data is still too high.

Wednesday, October 28, 2015

White House Invites Michael J. Fox to Reflect on Research and Hope - Why isn't stroke there?

Stroke has vastly more people affected by it than Parkinsons yet our stroke associations are so fucking incompetent they can't get any visibility. I'd say that is because they keep saying everything is coming up roses because of F.A.S.T. and tPA. When the truth is that everything in stroke is a failure and they refuse to acknowledge that.
https://www.michaeljfox.org/foundation/news-detail.php?today-we-re-in-the-future&
Approximately 60,000 Americans are diagnosed with Parkinson's each year.
800,000 Americans have a stroke each year. 13.3 times more stroke patients each year than Parkinsons. Yet our stroke associations have no clue how to get stroke to the tipping point.

Saturday, August 22, 2015

A Harvard neuroscientist told us the major ways meditation changes your brain

Amy has been beating on this for years, maybe this might be the tipping point.
http://www.businessinsider.com.au/harvard-neuroscientist-sara-lazar-meditation-interview-2015-8
Mindfulness meditation is incredibly popular right now.

According to the National Institute of Health, 18 million people in the US have meditated, or 8% of the population.

Studies suggests that the practice lessens stresses, increases memory, and may even help prevent genetic damage related to cancer.

While there is an ever-increasing amount of academic research around the practice and its effects, scientists are still figuring out what precisely is happening when people meditate, and what effects that behaviour has on the brain.

Harvard neuroscientist Sara Lazar, a leading researcher in the field, is one of the first to show that meditation practice produces structural changes in the brain.

In 2005, her team was the first to show how long-term meditation practice correlates with cortical thickening in brain areas associated with attention, sensory processing, and interoception (the awareness someone has about the physiological state of their body).

In a 2011 paper, she found that people who learned meditation for the first time in an eight-week course had increases in grey matter concentration in areas of the brain associated with “learning and memory processes, emotion regulation, self-referential processing, and perspective taking.”

The research suggests that “changes in brain structure may underlie some of these reported improvements and that people are not just feeling better because they are spending time relaxing,” Lazar says.

Those changes to brain structure come with big changes in mental activity.

Lazar revealed a few of them to Tech Insider:

Understanding yourself (and other people too). Meditation increases your awareness of “minimally conscious thoughts and emotions,” or quieter emotions that otherwise go unnoticed. “You have probably experienced many emotions that you’re not even aware of,” Lazar says. “If you understand them in yourself, you’ll understand them better in other people.”
• Emotional strength. When you have a higher resolution image of your emotional landscape, then you’re less to be swayed by each individual feeling. “If you have a better handle of all the different emotions, you realise, ‘OK, this emotion isn’t useful,'” Lazar says. “It gives you more information, and information is power.”
Getting less freaked out by stress. “You’re less likely to make a rash decision,” Lazar says. “You’re less stressed, you’re less caught up in the hullabaloo around you. I think that’s important regardless of what you do. it plays into quality of life. I still get stressed, but it takes more to make me stressed out.”

Lazar is careful to note that your brain changes when you learn anything, be it a second language or juggling. Same with meditation: though it can be an intimidatingly abstract activity when you first encounter it, mindfulness meditation is an exercise that you can learn to get better at, just like swinging at a baseball.

It works like this.

“You pick one object,” Lazar says. “For many people, it’s breathing sensations. It doesn’t have to be that, but it’s the most common thing to start with. You notice that, and your mind is going to get bored, and it’s going to start wandering, and then you realise, oh, my mind is starting to wander, and bring it back to breath.”

Instead of manipulating a bat to hit a ball, Lazar says that you’re using two of the mind’s go-to instruments: attention and metacognition, or your awareness of your own thoughts.

“Attention helps you stay focused, and metacognition helps you to see all the minimally conscious content,” Lazar says. “You think, this is boring, but what else is happening? You start to notice little thoughts and feeling happening in the back. They’re happening all the time, and we miss them 80% or 90% of the time. You notice there’s a lot more going on that you never saw before.”

Lazar has had a personal practice for nearly two decades, but she fell into meditation unexpectedly. When she and a friend over-trained for the Boston Marathon and ended up hurting themselves, Lazar started going to yoga to help recover.

Then she got into mindfulness meditation. “It was really clear that something in my brain had changed,” she tells Tech Insider. “I was noticing things I hadn’t noticed before, and I was less reactive to things that would piss me off.”

Lazar is careful to note that meditation is not a cure-all, in the same way that while exercise is a terrifically excellent thing to do for yourself, it’s not the only thing you should be doing for your overall well-being.

“It’s not you start meditation and you become a Buddhist monk,” Lazar says. “It will help promote attention and metacognition. The benefits are real and beneficial, but it’s not like you become a super person because of this.”

Watch Lazar’s 2011 TedX talk on meditation’s effects on the brain below.

Thursday, June 18, 2015

House shows bipartisan support of historic prioritization of Alzheimer’s disease

Because our stroke associations have totally failed us we have no positive articles like this. Stroke has not hit the tipping point because we always are bombarded with this 'happy talk' that all you have to do is get to a stroke hospital(F.A.S.T.) in 3 hours and you'll be made all better. What a FUCKING LIE!!! If you don't acknowledge that there are problems to be solved no one will be willing to help you.
Like all these f*cking problems in stroke that no one wants to talk about.
Or the fact that if you have a stroke right now you are screwed.
Or the fact that your doctor doesn't tell you anything about how to recover from a stroke.
http://www.alz.org/news_and_events_101507.asp?WT.mc_id=enews2015_06_17&
The House Labor, Health and Human Services (Labor-HHS) Appropriations Subcommittee today approved a historic $300 million increase for Alzheimer’s disease research as requested by Alzheimer’s Association advocates. If this increase becomes law, it will be the largest annual increase in federal Alzheimer’s research funding to date. The Alzheimer’s Association applauds this exemplary bipartisan effort to address this devastating and costly disease before Alzheimer’s prevalence triples and costs quadruple in just over a generation.

“In an act of true leadership, Chairman Cole and the bipartisan members of the subcommittee reached across the aisle today to change the trajectory of the Alzheimer’s epidemic,” said Harry Johns, president and CEO of the Alzheimer’s Association. “This bipartisan effort reflecting a more than a 50 percent increase in Alzheimer’s research funding shows that leaders on Capitol Hill are in agreement that the burden Alzheimer’s places on families and the nation must be addressed now.”

In March, more than 1,000 advocates from all 50 states gathered in the nation’s capital for the Alzheimer’s Association Advocacy Forum and asked their legislators for this increase of $300 million for Alzheimer’s research. The following month, Robert Egge, executive vice president of government affairs at the Alzheimer’s Association, testified before the House Labor, Health and Human Services (Labor-HHS) Appropriations Subcommittee, outlining the unique triple threat that Alzheimer’s disease poses:

  • More than 5 million Americans and their 15 million unpaid caregivers are affected by Alzheimer’s disease.
  • Already the most expensive disease in the country, according to the New England Journal of Medicine, the cost of Alzheimer’s to the nation will soar to $1.1 trillion by 2050, threatening family savings and the future of Medicare.
  • Alzheimer’s is the only leading cause of death that cannot be prevented, cured or even slowed.

Earlier this year, the Alzheimer’s Association released Changing the Trajectory of Alzheimer's Disease: How a Treatment by 2025 Saves Lives and Dollars,(Stroke has NO plan) which reported that the United States could save $220 billion within the first five years of a treatment for Alzheimer’s disease being introduced. The report shows that meeting the goal of the National Plan to Address Alzheimer’s Disease — to prevent and effectively treat Alzheimer’s by 2025 — would reduce the number of individuals affected by the disease by 2.5 million within the first five years of a treatment being available.

Currently, Alzheimer’s disease receives $586 million a year in federal funding for research. Leading scientists have said it will take a ramp up to $2 billion a year to reach the goal of the National Alzheimer's Plan(Stroke has NO plan).

Saturday, May 16, 2015

Advances in Concussion Research: An Applied Research Area With Significant Implications for the Future Conduct of Brain Science

With 3.8 million concussions per year in the US I guess this is vastly more important to write about than the 800,00 strokes per year. Or concussions have hit the tipping point when stroke is still sitting on the sidelines. Another failure of our stroke associations.
http://www.tandfonline.com/doi/full/10.1080/87565641.2015.1047713#.VVdx7Ub0KM8

Sunday, February 15, 2015

We're more scared of getting dementia in old age than any other disease such as stroke, cancer and heart disease -UK

Until we hit the tipping point of having stroke talked about as much as dementia will we ever get people to work on actual solutions for us. And this lack of visibility I lay directly on our stroke association failures. Mainly because they focus on being positive stating that with F.A.S.T. you can completely recover if you get to a stroke hospital fast enough. They are lying through their teeth. Less than 10% of those eligible for tPA get it and it only works completely to reverse all the effects of the stroke 12% of the time.  We should be stating how f*cking appalling it is that if you have a stroke right now you are screwed.

1 in 4 per WHO that has a stroke

 compared to the Americans aged 65 and over, 1 in 8 has Alzheimer’s,

 
http://www.dailymail.co.uk/health/article-2947718/We-scared-getting-dementia-old-age-disease.html

Wednesday, December 17, 2014

Alzheimer's disease

From the front page of Yahoo news. Alzheimers has obviously hit the tipping point. But if you look at the figures, stroke will have more people affected by 2050. Why hasn't stroke been more visible?
http://news.yahoo.com/video/alzheimer-39-disease-084835094.html
36 million people suffer from Alzheimer's around the world. According to a World Health Organisation estimate, this figure could reach 115 million by 2050 in the absence of a cure. With a new case diagnosed every 4 seconds, the disease remains one of medicine's greatest challenges as it robs ever more people of their memory and independence.VIDEOGRAPHIC
At 10 million survivors a year stroke will have 350 million survivors by 2050 and 175 million dead.
Sounds like a major catastrophe to me.