Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, March 13, 2026

Could cilostazol outperform aspirin after ischemic stroke in real-world care?

 Ask your completely incompetent? doctor. They better at a minimum know of this paper and discuss it cogently with you.
Let's see how long your doctor has been incompetent!

And this one is really a bitch for not delivering it NOW!

Two Cases Showing That Cilostazol Administration Leads to an Increase in Cerebral Blood Flow and Has a Positive Effect on Rehabilitation March 2024 

The latest here:

Could cilostazol outperform aspirin after ischemic stroke in real-world care?

OBJECTIVE

To compare clinical characteristics and outcomes associated with cilostazol versus aspirin in patients with ischemic stroke, with attention to carotid plaque progression, lipid metabolism, platelet aggregation, adverse events, and 12-month stroke recurrence.

METHODS

This retrospective study included 250 patients with ischemic stroke treated between August 2019 and April 2023, of whom 100 received cilostazol and 150 received aspirin according to routine clinical practice. Cilostazol was more commonly prescribed to patients with aspirin intolerance or perceived bleeding risk. Outcomes included changes in carotid plaque area and stenosis, lipid parameters, platelet function, adverse reactions, and recurrent ischemic stroke within 12 months.

RESULTS

At 12-month follow-up, patients receiving cilostazol showed greater reductions in carotid plaque area and stenosis rate compared with those receiving aspirin (P < 0.05). Differences were also observed in lipid profiles and platelet aggregation assays, with patterns consistent with the known pharmacological actions of cilostazol (P < 0.05). Adverse reactions, including bleeding events, pruritus, myalgia, and liver enzyme elevations, occurred less frequently in the cilostazol group (P < 0.05). Recurrent ischemic stroke was documented in 6.0% of cilostazol-treated patients and 20.0% of aspirin-treated patients (P < 0.05). These findings reflect associations observed in this real-world cohort and should be interpreted in light of underlying baseline differences and the non-randomized study design.

CONCLUSION

In this retrospective cohort, cilostazol use was associated with more favorable safety outcomes and lower recurrence rates compared with aspirin. Because treatment allocation was clinically driven and residual confounding cannot be excluded, the results indicate associations rather than causal effects. Prospective randomized studies are needed to determine whether these observed differences represent true treatment benefits.

REFERENCES

  1. Comparative effectiveness of cilostazol and aspirin in ischemic stroke: a retrospective cohort study.

    Wang Y, Chen H, Zhang X.

    Acta Neurol Belg. 2026 Mar 12 [Epub ahead of print]

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