Deans' stroke musings: Dietary antioxidants and risk of Parkinson's disease in two population-based cohorts

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, September 29, 2021

Dietary antioxidants and risk of Parkinson's disease in two population-based cohorts

With your risk of Parkinsons it is your hospital's responsibility to have the dietician create protocols on this.

Parkinson’s Disease May Have Link to Stroke March 2017

The latest here:

Dietary antioxidants and risk of Parkinson's disease in two population-based cohorts

Fei Yang MD, PhD, Alicja Wolk PhD, Niclas Håkansson PhD, Nancy L. Pedersen PhD, Karin Wirdefeldt MD, PhD,

First published: 07 September 2017

https://doi.org/10.1002/mds.27120

Citations: 51

The copyright line for this article was changed on 15 September 2017 after original online publication.

Funding agencies: : Suppported by the Swedish Research Council.

Relevant conflicts of interest/financial disclosures: : Nothing to report.

Full financial disclosures and author roles may be found in the online version of this article.

ABSTRACT

Background: A neuroprotective effect of dietary antioxidants on Parkinson's disease (PD) risk has been suggested, but epidemiological evidence is limited.

Objectives: To examine the associations between intake of dietary antioxidant vitamins and total antioxidant capacity and risk of PD.

Methods: We prospectively assessed the relationships of dietary antioxidant vitamins C and E, ß-carotene, and total antioxidant capacity with PD risk in two population-based cohorts (38,937 women and 45,837 men).

Results: During a mean 14.9-year follow-up period, 1,329 PD cases were identified. Dietary intake of ß-carotene was associated with a lower risk of PD (hazard ratio: 0.86; 95% confidence interval: 0.78-0.95; P_trend < 0.01 for women and hazard ratio: 0.91; 95% confidence interval: 0.84-0.99; P_trend = 0.05 for men). An inverse association between dietary vitamin E and PD risk was found in women (hazard ratio: 0.87; 95% confidence interval: 0.79-0.96; P_trend = 0.02). Dietary intake of vitamin C was inversely associated with PD risk in women at borderline significance (hazard ratio: 0.91; 95% confidence interval: 0.83-1.00; P_trend = 0.04). There was no association between dietary total antioxidant capacity and PD risk in either women (hazard ratio: 0.93; 95% confidence interval: 0.84-1.02; P_trend = 0.35) or men (hazard ratio: 1.00; 95% confidence interval: 0.93-1.07; P_trend = 0.97).

Conclusion: Intake of dietary vitamin E and ß-carotene was associated with a lower risk of PD. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Dietary antioxidants including vitamin C, E, and carotenoids have been suggested as neuroprotective agents for Parkinson's disease (PD) based on their property of reducing oxidative damage.1 Epidemiological evidence for a neuroprotective effect of dietary antioxidants on PD risk is, however, largely limited and inconsistent.2, 3 In addition, although not only vitamin C, E, and carotenes, but also several other compounds are dietary antioxidants, no previous study has yet examined the role of total dietary antioxidants on PD risk.

In this study, we estimated total antioxidant capacity (TAC) in a single estimate by taking into account summed effects of compounds from all relevant dietary antioxidants in the foods. We prospectively investigated the relationship of TAC, as well as the individual dietary antioxidant vitamins C and E and ß-carotene, with PD risk in two population-based cohorts.