Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, March 1, 2024

Cannabis Singled Out for Cardiovascular Risk

 Not enough information here to tell me if this cannabis use is smoked or an edible. So without that this click-bait title tells us nothing!

For my next stroke I will use cannabis for recovery.

Didn't your competent? doctor prescribe marijuana years ago to help your stroke recovery?  Oh, you don't have a functioning stroke doctor, do you? 

Cannabis Singled Out for Cardiovascular Risk

Findings independent of tobacco and e-cigarette use considered a "call to action"

A close up photo of a woman holding cannabis flowers

Cannabis use was independently linked to adverse cardiovascular outcomes in the general population even after accounting for tobacco cigarette and e-cigarette use, a large national study found.

Using data from the CDC's Behavioral Risk Factor Surveillance System (BRFSS), there was an increase in most incident cardiovascular disease events among adults using cannabis daily compared with non-users:

  • Coronary heart disease: adjusted OR 1.16, 95% CI 0.98-1.38
  • Myocardial infarction: adjusted OR 1.25, 95% CI 1.07-1.46
  • Stroke: adjusted OR 1.42, 95% CI 1.20-1.68
  • Composite of the three: adjusted OR 1.28, 95% CI 1.13-1.44

Evidence of an association between cannabis use and cardiovascular events persisted in non-tobacco smokers and younger people at risk of premature cardiovascular disease (men under 55 and women under 65), reported the study authors led by Abra Jeffers, PhD, a data analyst at Massachusetts General Hospital in Boston.

"We also accounted for number of days used per month as a continuous variable. This analysis is important, because it suggests that cannabis use alone may be a risk factor for adverse cardiovascular outcomes," Jeffers and team wrote in the Journal of the American Heart Associationopens in a new tab or window.

Of note, cannabis use has been rising while conventional tobacco use has decreased nationwide. According to the CDC, marijuana is the most commonly used federally illegal drug in the U.S., with 48.2 million people (or 18% of Americans) using it at least once in 2019.

"Despite common use, little is known about the risks of cannabis use and, in particular, the cardiovascular disease risks," said Jeffers in a press release from the American Heart Association (AHA). "Cannabis smoke is not all that different from tobacco smoke, except for the psychoactive drug: THC versus nicotine. Our study shows that smoking cannabis has significant cardiovascular risks, just like smoking tobacco."

The investigators noted that their study is consistent with older, smaller BRFSS studies supporting a relationship between cannabis and cardiovascular harms. Being three to 17 times larger, however, the present report had an adequate sample to show harms in the subgroup of tobacco and e-cigarette never-users.

"This is an important public health finding, particularly given our ongoing efforts to reduce the burden of heart disease in this country," said David Goff, MD, PhD, director of the National Heart, Lung, and Blood Institute's Division of Cardiovascular Sciences, in a statement.

Outside the CDC survey, other work has suggested that use of cannabis and other recreational substances is associated with early-onset atherosclerotic cardiovascular disease.

Yet cannabis is often undisclosed by patients. One French study showed that many recreational drug users with acute cardiovascular events landed in cardiac intensive care units without disclosing their drug use.

"As cannabis use continues to grow in legality and access across the U.S., practitioners and clinicians need to remember to assess cannabis use at each patient encounter in order to have a non-judgmental, shared decision conversation about potential cardiovascular risks and ways to reduce those risks," commented Robert Page II, PharmD, MSPH, of the University of Colorado School of Medicine in Aurora, in the AHA press release.

"The findings of this study have very important implications for population health and should be a call to action for all practitioners, as this study adds to the growing literature that cannabis use and cardiovascular disease may be a potentially hazardous combination," he added.

The population-based, cross-sectional study was based on data from the BRFSS covering 27 U.S. states and two territories. The analysis relied on data from the 2016 to 2020 telephone surveys, for which there were 434,104 respondents ages 18 to 74 years.

Overall, 55% of the respondents were ages 35-64, and 14.5% were ages 65-74; 51.1% were women, and 60.2% were white. The prevalence of daily and non-daily cannabis use was 4% and 7.1%, respectively.

Jeffers and colleagues acknowledged their reliance on self-reported cardiovascular conditions and cannabis use. Anonymous data also precluded linkage to mortality records for analysis.

Prospective cohort studies are needed to confirm their findings, they said.

  • author['full_name']

    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow

Disclosures

The study was funded by grants from the National Heart, Lung, and Blood Institute and the National Cancer Institute.

Jeffers had no disclosures.

Primary Source

Journal of the American Heart Association

Source Reference: opens in a new tab or windowJeffers AM, et al "Association of cannabis use with cardiovascular outcomes among US adults" J Am Heart Assoc 2024; DOI: 10.1161/JAHA.123.030178.

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