Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, October 15, 2025

Dietary supplementation with 6% blueberries (Vaccinium corymbosum L.) attenuates neurodegeneration and motor deficits in a Parkinson’s Disease model

 With your risk of Parkinsons post stroke, IS YOUR DOCTOR SMART ENOUGH TO INSTITUTE THIS PROTOCOL FOR YOU? NO?  Your doctor doesn't know about it and will do nothing! Fire that doctor and find someone intelligent!

Is your doctor that fucking incompetent about not knowing about the Parkinson's risk? Valid question; ask your doctor AND NOT POLITELY!

Your doctor, IF COMPETENT AT ALL, will know exactly what the fuck 6% means in this context!

Dietary supplementation with 6% blueberries (Vaccinium corymbosum L.) attenuates neurodegeneration and motor deficits in a Parkinson’s Disease model


https://doi.org/10.1016/j.tjnut.2025.10.015Get rights and content

Abstract

Background

Parkinson’s disease (PD) is a progressive neurodegenerative disorder associated with oxidative stress and neuroinflammation. Blueberries (Vaccinium corymbosum L.), rich in polyphenols and anthocyanins, have shown potential in mitigating these pathological processes.

Objective

To evaluate whether dietary supplementation with 6% freeze-dried blueberries attenuates motor impairment, dopaminergic denervation, and microglial activation in a 6-OHDA-induced rat model of PD.

Methods

Adult male Wistar rats were randomly assigned to a control group (standard rodent food) or a treatment group (6% blueberry-enriched diet). Hemiparkinsonism was induced via stereotaxic injection of 6-hydroxydopamine (6-OHDA) into the right striatum. Behavioral assessments (narrow beam test, apomorphine-induced rotations, and cylinder test) were conducted before and after surgery. Immunohistochemistry was performed to quantify tyrosine hydroxylase (TH) and Iba1 expression in the striatum and substantia nigra. Statistical analyze included two-way ANOVA and Student’s t-tests.

Results

Rats receiving 6% blueberries showed significantly fewer contralateral paw slips, reduced apomorphine-induced rotations, and lower motor asymmetry compared to controls (p < 0.05). Immunohistochemical analysis revealed decreased dopaminergic denervation and microglial activation in both brain regions. Behavioral improvements correlated with histological outcomes.

Conclusions

A diet enriched with 6% blueberries significantly mitigated motor deficits, dopaminergic neuron loss, and microglial activation in a 6-OHDA-induced rat model of PD. These findings highlight the potential of blueberry supplementation as a neuroprotective nutritional strategy in neurodegenerative disease models.

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