Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, April 29, 2022

New Research Identifies Blood Biomarker for Predicting Dementia Before Symptoms Develop

 This originally came out in August 2021, what is the current status?

Blood Test Discerns Alzheimer's From Other Dementia With High Accuracy

With your good chance of getting dementia this test should be prescribed by your doctor to establish a baseline for you. And then if found implement THOSE EXACT DEMENTIA PREVENTION PROTOCOLS  your doctor should have competently already set up.

Your risk of dementia, has your doctor told you of this?

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018

 

The latest here:

New Research Identifies Blood Biomarker for Predicting Dementia Before Symptoms Develop

Researchers have identified a blood biomarker that could help identify people with the earliest signs of dementia, even before the onset of symptoms.

The findings were published in the Journal of Alzheimer’s Disease.

Emer McGrath, MD, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland, and colleagues measured blood levels of P-tau181, a marker of neurodegeneration, in 52 cognitively healthy adults who were part of the US-based Framingham Heart Study, who later went on to have specialised brain positron emission tomography (PET) scans. The blood samples were taken from people who had no cognitive symptoms and who had normal cognitive testing at the time of blood testing.

The analysis found that elevated levels of P-tau181 in the blood were associated with greater accumulation of ß-amyloid on specialised brain scans. These scans were completed on average 7 years after the blood test.

Further analysis showed the biomarker P-tau181 outperformed t2other biomarkers in predicting signs of ß-amyloid on brain scans.

“The results of this study are very promising,” said Dr. McGrath. “P-tau181 has the potential to help us identify individuals at high risk of dementia at a very early stage of the disease, before they develop memory difficulties or changes in behaviour.”

The research team said the identification of a biomarker also points to the potential for a population screening programme.

“This study was carried out among people living in the community, reflecting those attending GP practices,” said Dr. McGrath. “A blood test measuring P-tau181 levels could potentially be used as a population-level screening tool for predicting risk of dementia in individuals at mid to late-life, or even earlier. This research also has important potential implications in the context of clinical trials. Blood levels of P-tau181 could be used to identify suitable participants for further research, including in clinical trials of new therapies for dementia. We could use this biomarker to identify those at a high risk of developing dementia but still at a very early stage in the disease, when there is still an opportunity to prevent the disease from progressing.”

Reference: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad215639

SOURCE: National University of Ireland Galway


No comments:

Post a Comment