Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, March 9, 2026

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

 Since this doesn't get spasticity cured; COMPLETELY FUCKING USELESS!

 Of course the infamous Dr. William M. Landau thinks spasticity is not worth treating. 

Do you believe in the do nothingism of Dr. William M. Landau on spasticity?  

His statement from here:

Spasticity After Stroke: Why Bother? Aug. 2004

Wonder if he will be singing the same tune after he becomes the 1 in 4 per WHO that has a stroke, will he be satisfied with not getting recovered?

If you get chosen, just keep asking for the cure for spasticity; you may need to scream at these idiots for useless research!

The latest  useless crapola here:

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

ClinicalTrials.gov IDNCT06055725
SponsorIpsen
Information Provided byIpsen Medical Director
Study Start (Actual)2023-11-01
Primary Completion (Estimated) 2027-11-30
Study Completion (Estimated)2027-11-30
Enrollment (Estimated)1051
Study TypeObservational
Last Update Posted2026-03-04

Study Overview

Brief Summary

This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain. The main aim of the study will be to find out how many of those who experience their first-ever stroke then go on to develop spasticity that would benefit from treatment with medication. Spasticity is a common post-stroke condition that causes stiff or ridged muscles. The results of this study will provide a standard guideline on the best way to monitor the development of post-stroke spasticity.

Contacts and Locations

Contact Information

Study Contact

NameIpsen Clinical Study Enquiries

PhoneSee e mail

Study Contact Backup

NameNot available

PhoneNot available

United States Locations

California

Anderson, California, United States 92354

Loma Linda

Los Angeles, California, United States 90095

University Of California, Los Angeles Medical Center

Florida

Florida City, Florida, United States 13330

University of South Florida (USF) - Morsani Center (USF Health Carol and Frank Morsani Center for Advanced Healthcare)

Rockledge, Florida, United States 32955

Knight Neurology

Georgia

Atlanta, Georgia, United States 30329-2206

Emory University Merge

Maryland

Hyattsville, Maryland, United States 20782

Medstar Health Research Institute, Inc

Massachusetts

Boston, Massachusetts, United States 02114

Massachusetts General Hospital

Boston, Massachusetts, United States 02129

Spaulding Rehabilitation Hospital

Minnesota

Rochester, Minnesota, United States 55905

Mayo Clinic

Missouri

Columbia, Missouri, United States 65212

University of Missouri Health Care

Nebraska

Omaha, Nebraska, United States 68114

Methodist Physicians Clinic

Omaha, Nebraska, United States 68118

Madonna Rehabilitation Hospital - Omaha Campus

North Carolina

Durham, North Carolina, United States 27705

Duke University School of Medicine

Ohio

Centerville, Ohio, United States 45459

Dayton Center for Neurological Disorders

Pennsylvania

Elkins Park, Pennsylvania, United States 19027

Moss Rehab

South Carolina

Charleston, South Carolina, United States 29425

Medical University of South Carolina

Texas

Dallas, Texas, United States 75390-8869

The University Of Texas Southwestern Medical Center

Houston, Texas, United States 77030

McGovern Medical School - UT Physicians - Neurology (Adult Neurology Clinic) - Texas Medical Center Location

San Antonio, Texas, United States 78229

The University of Texas Health Science Center

Utah

Salt Lake City, Utah, United States 84112

University Of Utah

Wisconsin

Milwauke, Wisconsin, United States 53226

Medical College of Wisconsin

Participation Criteria

Eligibility Criteria

Inclusion Criteria:

  • Participant must be aged 18 to 90 years at the time of providing informed consent
  • First-ever clinical stroke, defined according to World Health Organization criteria as rapidly developing clinical signs of focal (at times global) disturbance of cerebral function lasting more than 24 hours, within the past 4 weeks;
  • Confirmed paresis of the arms and/or legs which does not resolve within 1 day, according to the NIHSS score (a score of > 0 on Question 5 or 6 of the scale) within 2 weeks after the stroke
  • Capable of giving informed consent which includes compliance with the requirements and restrictions listed in the ICF and in this protocol

Exclusion Criteria:

  • Upper or lower extremity functional impairment prior to stroke per investigator judgement (e.g., modified Rankin Scale >2);
  • Presence of significant/major neurological impairment that might affect muscle tone (other than limb paresis);
  • Severe multi-impairment or diminished physical condition before stroke that could have caused paresis/spasticity/motor deficit per investigator judgement;
  • Life expectancy of less than 12 months as a result of severity of stroke or other illnesses (e.g. cardiac disease, malignancy, etc.)
  • Participation in any interventional study

Ages Eligible for Study

Minimum Eligible Age Not available

Maximum Eligible Age Elderly

Age Groups adult, older_adult

Eligible Sexes all

Accepts Healthy VolunteersNo

Sampling Method Non-Probability Sample

Study Population

The Main Population will be participants aged 18 to 90 years with confirmed paresis within 2 weeks after a first-ever clinical stroke that has occurred within the past 4 weeks

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