Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, March 23, 2023

Restless Legs a New Modifiable Risk Factor for Dementia?

 With your already higher risk of dementia post stroke, is your doctor testing for this? And what EXACTLY is your doctor's protocol for preventing dementia? Doesn't have one! You don't have a functioning stroke doctor! Why are you seeing them if they are that incompetent?

Your risk of dementia, has your doctor told you of this?

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

Your risk of Parkinsons here:

Parkinson’s Disease May Have Link to Stroke March 2017 

The latest here:

Restless Legs a New Modifiable Risk Factor for Dementia?

Restless legs syndrome (RLS) is associated with an elevated risk of dementia among older adults, suggesting the disorder may be a risk factor for dementia or a very early noncognitive sign of dementia, researchers say.

In a large population-based cohort study, adults with RLS were significantly more likely to develop dementia over more than a decade than their peers without RLS.

If confirmed in future studies, "regular check-ups for cognitive decline in older patients with RLS may facilitate earlier detection and intervention for those with dementia risk," investigators led by Eosu Kim, MD, PhD, with Yonsei University College of Medicine, Seoul, Republic of Korea, write.

The study was published online March 6 in Alzheimer's Research and Therapy.

Sleep Disorders and Dementia

RLS is associated with poor sleep, depression/anxiety, poor diet, microvasculopathy, and hypoxia ― all of which are known risk factors for dementia. However, the relationship between RLS and incident dementia has been unclear.

The researchers compared risk for all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VaD) among 2501 adults with newly diagnosed RLS and 9977 matched control persons participating in the Korean National Health Insurance Service–Elderly Cohort (KHIS-EC), a nationwide population-based cohort of adults aged 60 and older.

The mean age of the cohort was 73 years; most of the participants were women (65%). Among all 12,478 participants, 874 (7%) developed all-cause dementia during follow-up ― 475 (54%) developed AD, and 194 (22%) developed VaD.

The incidence of all-cause dementia was significantly higher among the RLS group than among the control group (10.4% vs 6.2%). Incidence rates of AD and VaD (5.6% and 2.6%, respectively) were also higher in the RLS group than in the control group (3.4% and 1.3%, respectively).

In Cox regression analysis, RLS was significantly associated with an increased risk of all-cause dementia (adjusted hazard ratio [aHR], 1.46; 95% CI, 1.24 – 1.72), AD (aHR 1.38; 95% CI, 1.11 – 1.72) and VaD (aHR, 1.81; 95% CI, 1.30 – 2.53).

The researchers note that RLS may precede deterioration of cognitive function, leading to dementia, and they suggest that RLS could be regarded as a "newly identified" risk factor or prodromal sign of dementia.

Modifiable Risk Factor

Reached for comment, Thanh Dang-Vu, MD, PhD, professor and research chair in sleep, neuroimaging, and cognitive health at Concordia University, in Montreal, Canada, said there is now "increasing literature that shows sleep as a modifiable risk factor for cognitive decline.

"Previous evidence indicates that both sleep apnea and insomnia disorder increase the risk for cognitive decline and possibly dementia. Here the study adds to this body of evidence linking sleep disorders to dementia, suggesting that RLS should also be considered as a sleep-related risk factor," Dang-Vu told Medscape Medical News.

"More evidence is needed, though, as here, all diagnoses were based on national health insurance diagnostic codes, and it is likely there were missed diagnoses for RLS but also for other sleep disorders, as there was no systematic screening for them," Dang-Vu cautioned.

Support for the study was provided by the Ministry of Health and Welfare, the Korean government, and Yonsei University College of Medicine. Kim and Dang-Vu report no relevant financial relationships.

Alzheimers Res Ther. Published online March 6, 2023. Full text

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