Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, May 22, 2020

Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain

What EXACT PROTOCOL is your doctor prescribing to remove this cerebral atherosclerosis? Research is 13 and 20 years old, how come your doctor has done nothing in that amount of time? How fucking incompetent is your doctor and hospital? A serious question; ask them!

I'm using watermelon  but since there is no clinical study on it, I'm just guessing on amounts.

Watermelon juice reverses hardening of the arteries  Nov. 2011 

Another here:

Hebrew University Researcher Finds 'Sweet' Way To Help Prevent Heart Disease, fruit known in Hebrew as pomelit December 2004 

The latest here:

Shared proteomic effects of cerebral atherosclerosis and Alzheimer’s disease on the human brain

Nature Neuroscience (2020)Cite this article




Abstract

Cerebral atherosclerosis contributes to dementia via unclear processes. We performed proteomic sequencing of dorsolateral prefrontal cortex in 438 older individuals and found associations between cerebral atherosclerosis and reduced synaptic signaling and between RNA splicing and increased oligodendrocyte development and myelination. Consistently, single-cell RNA sequencing showed cerebral atherosclerosis associated with higher oligodendrocyte abundance. A subset of proteins and modules associated with cerebral atherosclerosis was also associated with Alzheimer’s disease, suggesting shared mechanisms.

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Data availability

Phenotype data are available at: https://www.radc.rush.edu. Proteomic data from the discovery dataset (ROS/MAP cohorts) are available at https://www.synapse.org/#!Synapse:syn17015098. Proteomic data from the replication dataset (BLSA cohort) are available at https://www.synapse.org/#!Synapse:syn11209141.

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