Deans' stroke musings: Glial and Neuronal Control of Brain Blood Flow

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, May 21, 2020

Glial and Neuronal Control of Brain Blood Flow

It has been almost 10 years, has your incompetent doctor and stroke hospital done anything with this? My definition of incompetence is not following AND implementing research. Your hospital might just be following the status quo and considers that good enough. IT IS NOT!

Do you prefer your incompetence NOT KNOWING OR NOT DOING?

Oops, I'm not playing by the polite rules of Dale Carnegie, 'How to Win Friends and Influence People'.

Politeness will never solve anything in stroke. Yes, I'm a bomb thrower and proud of it. Someday a stroke "leader" will ream me out for being truthful by making them look bad, I look forward to that day.

The latest here:

Glial and Neuronal Control of Brain Blood Flow

David Attwell¹, Alastair M Buchan, Serge Charpak, Martin Lauritzen, Brian A Macvicar, Eric A Newman

. 2010 Nov 11;468(7321):232-43.

doi: 10.1038/nature09613.

Affiliations

PMID: 21068832
PMCID: PMC3206737
DOI: 10.1038/nature09613

Free PMC article

Abstract

Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these cells control blood flow is crucial for understanding how neural computation is powered, for interpreting functional imaging scans of brains, and for developing treatments for neurological disorders. It is now recognized that neurotransmitter-mediated signalling has a key role in regulating cerebral blood flow, that much of this control is mediated by astrocytes, that oxygen modulates blood flow regulation, and that blood flow may be controlled by capillaries as well as by arterioles. These conceptual shifts in our understanding of cerebral blood flow control have important implications for the development of new therapeutic approaches.