Your chances of getting dementia.
1. A documented 33% dementia chance post-stroke from an Australian study? May 2012.
2. Then this study came out and seems to have a range from 17-66%. December 2013.
3. A 20% chance in this research. July 2013.
2. Then this study came out and seems to have a range from 17-66%. December 2013.
3. A 20% chance in this research. July 2013.
TBI Is Associated With Increased Dementia Risk for Decades After Injury
January 31, 2018
SAN
FRANCISCO -- January 31, 2018 -- Traumatic brain injury (TBI) increases
the risk of a dementia diagnosis for more than 30 years after a trauma,
though the risk of dementia decreases over time, according to a study
published this week in PLOS Medicine.
Although TBI has been associated with dementia, the details of that risk over time and in different TBI types have not been well studied.
For the current study, Anna Nordström, Umeå University, Umeå, Sweden, and colleagues tracked all diagnoses of dementia and TBI in Swedish nationwide databases from 1964 through 2012.
In a retrospective cohort, 164,334 individuals with TBI were matched with control participants who did not have TBI; in a case-control cohort, 136,233 individuals diagnosed with dementia at follow-up were matched with control participants who did not develop dementia; and in a third cohort, the researchers studied 46,970 sibling pairs with one individual having a TBI.
In the first year after TBI, the risk of dementia is increased by 4- to 6-fold. Thereafter, the risk decreased rapidly but was still significant more than 30 years after the TBI.
Overall, the risk of dementia diagnosis was increased by about 80% during a mean follow-up period of 15 years.
The risk of dementia was higher for those with a severe TBI or multiple TBIs and was similar in men and women.
Because the development of dementia can be a risk factor for accidents resulting in TBI, it’s likely that in some cases, the onset of dementia preceded the TBI, so the researchers caution against making causal inferences.
“The findings of this study suggest an existence of a time- and dose-dependent risk of developing dementia more than 30 years after TBI,” the authors wrote. “To our knowledge, no previous prospective study with similar power and follow-up time has been reported.”
Reference: https://doi.org/10.1371/journal.pmed.1002496
SOURCE: PLOS
Although TBI has been associated with dementia, the details of that risk over time and in different TBI types have not been well studied.
For the current study, Anna Nordström, Umeå University, Umeå, Sweden, and colleagues tracked all diagnoses of dementia and TBI in Swedish nationwide databases from 1964 through 2012.
In a retrospective cohort, 164,334 individuals with TBI were matched with control participants who did not have TBI; in a case-control cohort, 136,233 individuals diagnosed with dementia at follow-up were matched with control participants who did not develop dementia; and in a third cohort, the researchers studied 46,970 sibling pairs with one individual having a TBI.
In the first year after TBI, the risk of dementia is increased by 4- to 6-fold. Thereafter, the risk decreased rapidly but was still significant more than 30 years after the TBI.
Overall, the risk of dementia diagnosis was increased by about 80% during a mean follow-up period of 15 years.
The risk of dementia was higher for those with a severe TBI or multiple TBIs and was similar in men and women.
Because the development of dementia can be a risk factor for accidents resulting in TBI, it’s likely that in some cases, the onset of dementia preceded the TBI, so the researchers caution against making causal inferences.
“The findings of this study suggest an existence of a time- and dose-dependent risk of developing dementia more than 30 years after TBI,” the authors wrote. “To our knowledge, no previous prospective study with similar power and follow-up time has been reported.”
Reference: https://doi.org/10.1371/journal.pmed.1002496
SOURCE: PLOS
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