Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, May 3, 2022

Seven hours of sleep is optimal in middle and old age, say researchers

What is your doctor's sleep protocol? Mine seemed to be, hand out sleeping pills like candy at 10pm, then have the vampire squad come in at 7am to steal blood from at least one person in the quad. Turning on the lights in the process, clinical staff efficiency, not patient wellbeing.  Do sleeping pills provide decent sleep? Why doesn't your doctor know that answer?

 

Seven hours of sleep is optimal in middle and old age, say researchers


 




April 28, 2022
Seven hours of sleep is optimal in middle and old age, say researchers

by University of Cambridge
Credit: Unsplash/CC0 Public Domain

Seven hours is the ideal amount of sleep for people in their middle age and upwards, with too little or too much little sleep associated with poorer cognitive performance and mental health, say researchers from the University of Cambridge and Fudan University.

Sleep plays an important role in enabling cognitive function and maintaining good psychological health. It also helps keep the brain healthy by removing waste products. As we get older, we often see alterations in our sleep patterns, including difficulty falling asleep and staying asleep, and decreased quantity and quality of sleep. It is thought that these sleep disturbances may contribute to cognitive decline and psychiatric disorders in the aging population.

In research published today in Nature Aging, scientists from the UK and China examined data from nearly 500,000 adults aged 38-73 years from the UK Biobank. Participants were asked about their sleeping patterns, mental health and well-being, and took part in a series of cognitive tests. Brain imaging and genetic data were available for almost 40,000 of the study participants.

By analyzing these data, the team found that both insufficient and excessive sleep duration were associated with impaired cognitive performance, such as processing speed, visual attention, memory and problem-solving skills. Seven hours of sleep per night was the optimal amount of sleep for cognitive performance, but also for good mental health, with people experiencing more symptoms of anxiety and depression and worse overall well-being if they reported sleeping for longer or shorter durations.

The researchers say one possible reason for the association between insufficient sleep and cognitive decline may be due to the disruption of slow-wave—'deep'—sleep. Disruption to this type of sleep has been shown to have a close link with memory consolidation as well as the build-up of amyloid—a key protein which, when it misfolds, can cause 'tangles' in the brain characteristic of some forms of dementia. Additionally, lack of sleep may hamper the brain's ability to rid itself of toxins.

The team also found a link between the amount of sleep and differences in the structure of brain regions involved in cognitive processing and memory, again with greater changes associated with greater than or less than seven hours of sleep.

Having a consistent seven hours' sleep each night, without too much fluctuation in duration, was also important to cognitive performance and good mental health and well-being. Previous studies have also shown that interrupted sleep patterns are associated with increased inflammation, indicating a susceptibility to age-related diseases in older people.

Professor Jianfeng Feng from Fudan University in China said: "While we can't say conclusively that too little or too much sleep causes cognitive problems, our analysis looking at individuals over a longer period of time appears to support this idea. But the reasons why older people have poorer sleep appear to be complex, influenced by a combination of our genetic makeup and the structure of our brains."

The researchers say the findings suggest that insufficient or excessive sleep duration may be a risk factor for cognitive decline in aging. This is supported by previous studies that have reported a link between sleep duration and the risk of developing Alzheimer's disease and dementia, in which cognitive decline is a hallmark symptom.

 Professor Barbara Sahakian from the Department of Psychiatry at the University of Cambridge, one of the study's authors, said: "Getting a good night's sleep is important at all stages of life, but particularly as we age. Finding ways to improve sleep for could be crucial to helping them maintain good and well-being and avoiding cognitive decline, particularly for patients with and dementias."

 
Inverted U-shaped link seen for sleep duration, cognitive decline
More information: Wei Cheng, The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health, Nature Aging (2022). DOI: 10.1038/s43587-022-00210-2. www.nature.com/articles/s43587-022-00210-2
Journal information: Nature Aging

Provided by University of Cambridge

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