What is your doctors fall prevention protocol? DO YOU HAVE ANY? Or are you practicing perfection rather than error based learning?
Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis
Objective To investigate the effect of whole-body vibration exercise (WBV) on fracture risk in adults ≥50 years of age.
Design
A systematic review and meta-analysis calculating relative risk ratios,
fall rate ratio and absolute weighted mean difference using random
effects models. Heterogeneity was estimated using I2
statistics, and the Cochrane Collaboration’s risk of bias tool and the
GRADE approach were used to evaluate quality of evidence and summarise
conclusions.
Data sources
The databases PubMed, Embase and the Cochrane Central Register from
inception to April 2016 and reference lists of retrieved publications.
Eligibility criteria for selecting studies
Randomised controlled trials examining the effect of WBV on fracture
risk in adults ≥50 years of age. The primary outcomes were fractures,
fall rates and the proportion of participants who fell. Secondary
outcomes were bone mineral density (BMD), bone microarchitecture, bone
turnover markers and calcaneal broadband attenuation (BUA).
Results
15 papers (14 trials) met the inclusion criteria. Only one study had
fracture data reporting a non-significant fracture reduction (risk ratio
(RR)=0.47, 95% CI 0.14 to 1.57, P=0.22) (moderate quality of evidence).
Four studies (n=746) showed that WBV reduced the rate of falls with a
rate ratio of 0.67 (95% CI 0.50 to 0.89, P=0.0006; I2=19%)
(moderate quality of evidence). Furthermore, data from three studies
(n=805) found a trend towards falls reduction (RR=0.76, 95% CI 0.48 to
1.20, P=0.24; I2=24%) (low quality of evidence). Finally,
moderate to low quality of evidence showed no overall effect on BMD and
only sparse data were available regarding microarchitecture parameters,
bone turnover markers and BUA.
Conclusions
WBV reduces fall rate but seems to have no overall effect on BMD or
microarchitecture. The impact of WBV on fractures requires further
larger adequately powered studies. This meta-analysis suggests that WBV
may prevent fractures by reducing falls.
PROSPERO registration number
CRD42016036320; Pre-results.
This
is an Open Access article distributed in accordance with the Creative
Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits
others to distribute, remix, adapt, build upon this work
non-commercially, and license their derivative works on different terms,
provided the original work is properly cited and the use is
non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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