Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, February 21, 2022

“Discovery consists in seeing what everyone else has seen and thinking what no one else has thought” —Albert Szent-Györgyi

 There is absolutely no discovery here. Nothing even remotely close to solving

the 5 causes of the neuronal cascade of death in the first days. Or working on creating 100% recovery protocols. In my opinion these were all worthless, tell me EXACTLY where my thinking is wrong, considering the only goal in stroke is 100% recovery.

Send me hate mail on this: oc1dean@gmail.com. I'll print your complete statement with name and my response in my blog. Or are you afraid to engage with my stroke-addled mind?

“Discovery consists in seeing what everyone else has seen and thinking what no one else has thought”

—Albert Szent-Györgyi

Progress depends on innovation. With that in mind, the journal Stroke is pleased to offer an award that is a visible and effective way of encouraging new paths, new methods and new ways of thinking. This Award is made possible by funding from the American Heart Association | American Stroke Association to whom we are grateful.

Congratulations to the recipients!

2021

First prize: Naoki Kaneko and Sandro Satta
Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection

Spotlight: Q&A with Naoki Kaneko and Sandro Satta

Second prize: Stefan J. Blaschke and Lukas Hensel
Translating Functional Connectivity After Stroke: Functional Magnetic Resonance Imaging Detects Comparable Network Changes in Mice and Humans

Spotlight: Q&A with Stefan J. Blaschke and Lukas Hensel

Third prize: Cathy S. Zhong and James Beharry
Routine Use of Tenecteplase for Thrombolysis in Acute Ischemic Stroke

Spotlight: Q&A with Cathy S. Zhong and James Beharry

2020

First prize: Brian Mac Grory
Intravenous Fibrinolysis for Central Retinal Artery Occlusion: A Cohort Study and Updated Patient-Level Meta-Analysis

Spotlight: Q&A with Brian Mac Grory

Second prize: Tongyu Zhang and Pei Wu
Mitophagy Reduces Oxidative Stress Via Keap1 (Kelch-Like Epichlorohydrin-Associated Protein 1)/Nrf2 (Nuclear Factor-E2-Related Factor 2)/PHB2 (Prohibitin 2) Pathway After Subarachnoid Hemorrhage in Rats

Spotlight: Q&A with Tongyu Zhang and Pei Wu

Third prize: Keith L. Keene and Hyacinth I. Hyacinth
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke

Spotlight: Q&A with Keith L. Keene and Hyacinth I. Hyacinth

2019

First prize: Shubei Ma and Jianyi Wang
Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia

Spotlight: Q&A with Shubei Ma and Jianyi Wang

Second prize: Gregory Y.H. Lip
Effectiveness and Safety of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients: The ARISTOPHANES Study

Spotlight: Q&A with Gregory Y.H. Lip

Third prize: Frieder Schlunk
Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage

Spotlight: Q&A with Frieder Schlunk

2018

First prize: Rajkumar Verma 
Inhibition of miR-141-3p Ameliorates the Negative Effects of Poststroke Social Isolation in Aged Mice

Spotlight: Q&A with Rajkumar Verma

Second prize: Isaac García-Yébenes
Iron Overload Exacerbates the Risk of Hemorrhagic Transformation After tPA (Tissue-Type Plasminogen Activator) Administration in Thromboembolic Stroke Mice

Spotlight: Q&A with Isaac García-Yébenes

Third prize: Achala Vagal
Collateral Clock Is More Important Than Time Clock for Tissue Fate: A Natural History Study of Acute Ischemic Strokes

Spotlight: Q&A with Achala Vagal

2017

First prize: Marilena Marinescu 
Cerebral Microbleeds in Murine Amyloid Angiopathy: Natural Course and Anticoagulant Effects

Spotlight: Q&A with Marilena Marinescu

Second prize: Matthew P. Pase
Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study

Spotlight: Q&A with Matthew P. Pase

Third prize: Andrew Bivard
Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke

Spotlight: Q&A with Andrew Bivard

2016

First prize: Alexis N. Simpkins 
Identification of Reversible Disruption of the Human Blood– Brain Barrier Following Acute Ischemia

Spotlight: Q&A with Alexis N. Simpkins

Second prize: Xiangrong Liu
Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery After Cerebral Ischemia

Spotlight: Q&A with Xiangrong Liu

Third prize: Gary K. Steinberg
Clinical Outcomes of Transplanted Modified Bone Marrow–Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study

Spotlight: Q&A with Gary K. Steinberg

2015

First prize: Kevin B. Koronowski 
Resveratrol Preconditioning Induces a Novel Extended Window of Ischemic Tolerance in the Mouse Brain

Spotlight: Q&A with Kevin Koronowski

Second prize: Lucie A. van den Berg
Type of Anesthesia and Differences in Clinical Outcome After Intra-Arterial Treatment for Ischemic Stroke

Spotlight: Q&A with Lucie A. van den Berg

Third prize: Maurizio Paciaroni
Early Recurrence and Cerebral Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation: Effect of Anticoagulation and Its Timing: The RAF Study

Spotlight: Q&A with Maurizio Paciaroni

2014

First prize: Dominique A. Cadilhac 
Evaluation of Rural Stroke Services: Does Implementation of Coordinators and Pathways Improve Care in Rural Hospitals?

Spotlight: Q&A with Dr. Cadilhac

Second prize: Kristina Dupont Hougaard
Remote Ischemic Perconditioning as an Adjunct Therapy to Thrombolysis in Patients With Acute Ischemic Stroke: A Randomized Trial

Spotlight: Q&A with Dr. Hougaard

Third prize: Haiping Zhao
Ischemic Postconditioning Relieves Cerebral Ischemia and Reperfusion Injury Through Activating T-LAK Cell–Originated Protein Kinase/Protein Kinase B Pathway in Rats

Spotlight: Q&A with Dr. Zhao

2013

First prize: Marius de Groot and Benjamin F. J. Verhaaren
Changes in Normal-Appearing White Matter Precede Development of White Matter Lesions

Second prize: Ya-Ling Lee
Dental Prophylaxis and Periodontal Treatment Are Protective Factors to Ischemic Stroke

Third prize: Novella Calcinaghi
Multimodal Imaging in Rats Reveals Impaired Neurovascular Coupling in Sustained Hypertension

2012

First prize: Julie Tilson
Characterizing and Identifying Risk for Falls in the LEAPS Study: A Randomized Clinical Trial of Interventions to Improve Walking Poststroke

Second prize: Hiroyuki Sakata
Neural Stem Cells Genetically Modified to Overexpress Cu/Zn-Superoxide Dismutase Enhance Amelioration of Ischemic Stroke in Mice

Third prize: H. Bart Brouwers
Apolipoprotein E Genotype Predicts Hematoma Expansion in Lobar Intracerebral Hemorrhage

2011

First prize: David S. Liebeskind
CT and MRI Early Vessel Signs Reflect Clot Composition in Acute Stroke

Second prize: Gary A. Ford
Intravenous Alteplase for Stroke in Those Older Than 80 Years Old

Third prize: Yu Hasegawa
Preservation of Tropomyosin-Related Kinase B (TrkB) Signaling by Sodium Orthovanadate Attenuates Early Brain Injury After Subarachnoid Hemorrhage in Rats

2010

First prize: Alex Zacharek, Amjad Shehadah and Jieli Chen share first authorship
Comparison of Bone Marrow Stromal Cells Derived From Stroke and Normal Rats for Stroke Treatment

Second prize: Thomas M. Hemmen
Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke (ICTuS-L): Final Results

Third prize: J. David Spence
Treating Arteries Instead of Risk Factors: A Paradigm Change in Management of Atherosclerosis

2009

First prize: Gretchen E. Tietjen
Migraine and Biomarkers of Endothelial Activation in Young Women

Second prize: Jorge Kattah
HINTS to Diagnose Stroke in the Acute Vestibular Syndrome: Three-Step Bedside Oculomotor Examination More Sensitive Than Early MRI Diffusion-Weighted Imaging

Third prize: Nancy Mayo
A Longitudinal View of Apathy and Its Impact After Stroke

2008

First prize: Laurent Pierot
Immediate Clinical Outcome of Patients Harboring Unruptured Intracranial Aneurysms Treated by Endovascular Approach: Results of the ATENA Study

Second prize: Charlie Thompson
Living Beyond Our Physiological Means: Small Vessel Disease of the Brain Is an Expression of a Systemic Failure in Arteriolar Function: A Unifying Hypothesis

No third prize awarded.

 
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