Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, February 25, 2022

Effects of Intermittent Fasting On Cognition and Neurodegeneration

Only 24 references so your doctor can competently discuss those with you to see if the correct conclusions were drawn.

Effects of Intermittent Fasting On Cognition and Neurodegeneration

Dureshahwar Kanwar Aga Khan University Pakistan Mohammad Wasay Aga Khan University Pakistan Follow this and additional works at: https://ecommons.aku.edu/pjns Part of the Neurology Commons Recommended Citation Kanwar, Dureshahwar and Wasay, Mohammad (2021) "Effects of Intermittent Fasting On Cognition and Neurodegeneration," Pakistan Journal of Neurological Sciences (PJNS): Vol. 16 : Iss. 3 , Article 8. Available at: https://ecommons.aku.edu/pjns/vol16/iss3/8

ABSTRACT:  

Intermittent fasting (IF) can facilitate neurodegenerative, neuroadaptive and neuroprotective processes leading to profound effects on cognition and dementias. The impact that IF has on the central nervous system is still not fully known. Several factors come into likely effect including changes in energy metabolism, oxidative damage, insulin sensitivity, inflammation, and functional changes related to various neurotransmitters and hormones. During IF ketones are produced in large quantities and the brain consumes these for energy. The presence of ketone bodies increases the expression of the genes for brain derived neurotrophic factor which has a powerful effect on dementia and cognition. Brain derived neurotrophic factor (BDNF) in the hippocampus, the striatum, and cerebral cortex affects learning capabilities and memory. This process is enhanced by IF. IF also has multiple effects on the endocrine wellbeing, including control of hypertension, metabolic syndrome, insulin resistance and dyslipidemia. In ancient times, fasting was a common practice but with recent cellular studies the beneficial effects on the brain of IF are being truly proven. In a world of costly health care with an increase in neurological disorders, IF could be an effective therapy that is multi targeted, self-controlled and cost free .Further research is required to question the effect of IF in the long-term and whether pharmaceuticals can come up with safer medication options that imitate the effects of IF without a drastic change in the eating patterns.

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