Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 33,242 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
1. Department of Neurology, Handan Central Hospital, Handan, China
2. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Abstract
Background:
Inflammation has an important impact on the pathological progression associated with ischemic stroke. Serum uric acid (UA) to lymphocyte ratio (ULR) is a biomarker that responds to the level of inflammation but is not definitively associated with the clinical outcomes in patients with acute ischemic stroke (AIS).
Methods:
The data were obtained from the Third China National Stroke Registry (CNSR-III). Enrolled AIS patients were grouped by ULR quartiles at admission. The outcomes were poor functional outcomes (modified Rankin Scale [mRS] score of 3–6 or 2–6) and all-cause mortality at 3 months and 1 year. The associations of ULR with the risk of poor functional outcome and all-cause mortality were analyzed by multivariable logistic regression and Cox proportional hazards regression.
Results:
A total of 8,241 patients were included from the CNSR-III study. After adjusting for confounders, it was found that patients in the highest ULR quartile had higher mRS scores of 2–6 (odds ratio [OR], 1.33; 95% confidence interval [CI], 1.15–1.53) and 3–6 (OR, 1.35; 95% CI, 1.16–1.57) at the 3-month follow-up. Additionally, the highest ULR quartile was associated with an increased risk of all-cause mortality at the 3-month follow-up (hazard ratio [HR], 1.97; 95%CI, 1.22–3.18). Similar results were observed at the 1-year follow-up.
Conclusion:
Elevated ULR increased the risks of poorer functional outcomes and all-cause mortality in the AIS patients. However, this observational study was limited by potential unmeasured confounders, selection bias, residual confounding, and restricted generalizability to other populations.
Look at it yourself, you can see it has no objectivity at all and nothing that could generate an EXACT RECOVERY PROTOCOL! In my opinion; TOTALLY WORTHLESS!
You need to determine which of these nine options is causing your problems.
The exact same deficit could have 9 causes.
See this example of nine reasons for a movement disability:
You can't tell me these all have the same solution, I'm not that stupid. 1. Penumbra damage to the motor cortex. 2. Dead brain in the motor cortex. 3. Penumbra damage in the pre-motor cortex. 4. Dead brain in the pre-motor cortex. 5. Penumbra damage in the executive control area. 6. Dead brain in the executive control area. 7. Penumbra damage in the white matter underlying any of these three. 8. Dead brain in the white matter underlying any of these three. 9. Spasticity preventing movement from occurring.
Correspondence to Professor Jeremy Hobart, Clinical Neurology Research Group, Plymouth University Peninsula Schools of Medicine and Dentistry, Room N13 ITTC Building, Plymouth Science Park, Derriford, Plymouth PL6 8BX, UK; jeremy.hobart@plymouth.ac.uk
Abstract
Objective Despite a growing call to use patient-reported outcomes in clinical research, few are available for measuring upper limb function post-stroke. We examined the Disabilities of the Arm, Shoulder and Hand (DASH) to evaluate its measurement performance in acute stroke. In doing so, we compared results from traditional and modern psychometric methods.
Methods 172 people with acute stroke completed the DASH. Those with upper limb impairments completed the DASH again at 6 weeks (n=99). Data (n=271) were analysed using two psychometric paradigms: traditional psychometric (Classical Test Theory, CTT) analyses examined data completeness, scaling assumptions, targeting, reliability and responsiveness; Rasch Measurement Theory (RMT) analyses examined scale-to-sample targeting, scale performance and person measurement.
Results CTT analyses implied the DASH was psychometrically robust in this sample. Data completeness was high, criteria for scaling assumptions were satisfied (item-total correlations 0.55–0.95), targeting was good, internal consistency reliability was high (Cronbach's α=0.99) and responsiveness was clinically moderate (effect size=0.51). However, RMT analyses identified important limitations: scale-to-sample targeting was suboptimal, 4 items had disordered response category thresholds, 16 items exhibited misfit, 3 pairs of items had high residual correlations (>0.60) and 84 person fit residuals exceeded the recommended range.
Conclusions RMT methods identified limitations missed by CTT and indicate areas for improvement of the DASH as an upper limb measure for acute stroke. Findings, similar to those identified in multiple sclerosis, highlight the need for scales to have strong conceptual underpinnings, with their development and modification guided by sophisticated psychometric methods.
Father Muller Medical College Hospital (FMMCH) has been conferred the WSO Angels Diamond Award for Q1 2026, an international recognition jointly supported by the World Stroke Organization (WSO) and the Angels Initiative, for its outstanding excellence in stroke patient care(NOT RECOVERY!) and advanced neurovascular services as of Thursday, May 28.
A release here said the award recognises hospitals that demonstrate exceptional standards in acute stroke management through rapid diagnosis, timely treatment, evidence-based thrombolysis, mechanical thrombectomy services, multidisciplinary coordination, and superior patient outcomes. The recognition reflects the collaborative efforts of multiple departments working in unison, including the Departments of Emergency Medicine, Neurology, Neuroradiology, Critical Care, and General Medicine.
The advanced Stroke Unit at FMMCH is supported by state-of-the-art neuroimaging and interventional facilities, including a 3 Tesla MRI, CT Brain Perfusion Imaging, and a sophisticated Bi-plane Cath Lab. These facilities allow rapid diagnosis, accurate patient selection, and timely neuro-interventional procedures, including acute thrombolysis and mechanical thrombectomy.
FMMCH acknowledged the dedicated contributions of the core stroke care(NOT RECOVERY!) team, including Raghavendra B.S. and Vimala Colaco from the Department of Neurology, Shailaja S. from the Department of Emergency Medicine, and Ariharan K. from the Department of Interventional Neuro-Radiology, along with the Cath Lab team, nursing staff, technicians, emergency personnel, and the hospital administration.
Hospitals from countries outside the territory of the European Stroke Organisation that capture treatment data in RES-Q, SITS-QR, or other approved stroke registries are automatically considered for the WSO Angels awards based on stringent quality measures outlined in the tier system.
Developing sustainable bioelectronics that simultaneously integrate mechanical robustness, high conductivity, biocompatibility, and system-level functionality remains a fundamental challenge. Here, we report a Hofmeister-engineered, fully biobased hydrogel platform (GT2C20) that addresses these limitations through a synergistic dual physical cross-linking network. By combining citrate-induced chain compaction and continuous ionic transport pathways, this hydrogel achieves high tensile strength (0.73 MPa), large extensibility (272.5%), and high electrical conductivity (1.8 S m–1), overcoming intrinsic trade-offs in conventional gelatin-based systems. Building on these properties, GT2C20enables an integrated multifunctional bioelectronic system. As a skin-conformal bioelectrode, it provides high-fidelity acquisition of electrophysiological signals (ECG, EEG, and EMG), achieving a high signal-to-noise ratio (24.3 dB for ECG) compared to commercial Ag/AgCl electrodes. When integrated with deep learning algorithms, the platform enables autonomous assessment of Brunnstrom stages for stroke rehabilitation with an accuracy of 97.31%, while a wireless telemedicine system supports remote diagnosis and personalized healthcare management. In parallel, the hydrogel functions as a highly stable strain sensor for real-time motion monitoring and precise gesture recognition, enabling intuitive control of prosthetic devices. Additionally, the hydrogel acts as a triboelectric nanogenerator electrode, yielding an open-circuit voltage of 72.1 V to power its own functions, while a microcontroller system supports wireless telemedicine and remote rehabilitation monitoring. This work presents an eco-friendly strategy for fabricating high-performance, biobased flexible electronics suited for health monitoring, telemedicine, and soft robotics.
Daily cold exposure using cooling vests for 2 hours each morning over 6 weeks reduced body weight and body fat mass in adults with overweight or obesity. The intervention improved thermal comfort and cold-induced carbohydrate oxidation while reducing cold perception over time.
METHODOLOGY:
Cold exposure has gained attention as a possible way to decrease fat accumulation; however, previous studies involved lean participants or short-term interventions.
Researchers studied the effects of longer-term cold exposure in 47 adults with overweight or obesity (BMI, 25-35) who were randomly assigned either to the control group (n = 23) or the cold exposure group (n = 24). Participants wore a cooling vest and waist wrap with phase change material with 15 °C cooling pads for 2 hours each morning for 6 weeks.
Body composition was measured using bioimpedance and hepatic steatosis via FibroScan, and resting energy expenditure was evaluated at thermoneutrality (27 °C) and upon acute cold exposure (11 °C) before and after the intervention period.
Daily questionnaires assessed participants’ cold perception and thermal comfort.
Other measures included serum levels of glucose metabolism markers (eg, glucose and insulin) and lipid metabolism markers (eg, triglycerides, free fatty acids, total cholesterol, and low-density lipoprotein cholesterol), and whole blood was assessed for leukocyte count and lipopolysaccharide-induced cytokine release.
TAKEAWAY:
Compared with the control group, the cold exposure group had a reduced body weight by 1.6 ± 0.4 kg (P < .001) and BMI by 0.5 ± 0.1 (P < .001), attributed to a reduction in body fat mass of 1.5 ± 0.5 kg (P = .007), whereas fat-free mass remained unchanged.
Repeated cold exposure improved thermal comfort ratings of the cooling vest (P = .020) and decreased cold perception (P = .025).
Cold exposure did not result in changes in hepatic steatosis, circulating levels of markers related to glucose or lipid metabolism, leukocyte composition, or lipopolysaccharide-induced cytokine release in blood.
IN PRACTICE:
“In subjects with overweight or obesity, 6 weeks of daily cold exposure reduced body weight primarily by lowering body fat mass,” the authors of the study wrote.
SOURCE:
The study was led by Mariëtte Boon, Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, Netherlands. The findings were presented at the 33rd European Congress on Obesity (ECO) 2026.
My opinion about this opinion is that you are totally missing the best prevention out there! 100% RECOVERY! Are you really that blitheringly stupid you can't see that? Oops, I just dissed some professors, not sorry. Want to discuss; oc1dean@gmail.com
I know you'll ignore me because stroke patients know nothing. I've only got 20 years of experience, care to beat that?
You're supposed to completely solve problems, NOT just reduce the fall rate. In business not solving the problem completely would get you fired immediately! Hoping comeuppance hits you really hard when you are the 1 in 4 per WHO that has a stroke!
New evidence from the Falls After Stroke Trial shows that falls after stroke can be reduced with a tailored, home-based intervention.
Falls are one of Australia’s most serious and costly public health problems, and the leading cause of injury related hospitalisation and death among people aged 65 years and over. Each day, around 16 older Australians die following a fall and 400 are hospitalised. Fall‑related injuries in older Australians cost the health system more than $2 billion annually, with additional impacts on rehabilitation, aged care and informal caregiving.
The challenge of reducing falls after stroke is compounded by a lack of access to ongoing support (including allied health). Stroke survivors feel abandoned in the months and years following the stroke. If they choose to re-engage, they must navigate Australia’s complex and disjointed health and disability systems.
Falls prevention has remained a major gap in post stroke care. No previous intervention had been shown to prevent falls after stroke, and falls have often been viewed as an inevitable consequence.
FAST addressed previous limitations by reframing exercise as a habit rather than homework (PeopleImages/Shutterstock).
The Falls After Stroke Trial
The Falls After Stroke Trial (FAST), recently published in the BMJ, is set to change all that: it’s the first effectiveness trial worldwide to demonstrate that falls after stroke can be prevented.
Beginning in 2019, FAST recruited 370 community-dwelling stroke survivors aged over 50 and within five years of their first stroke across New South Wales, Victoria and the ACT and randomised them to usual care or a six-month, home-based intervention.
The intervention was delivered by occupational therapist–physiotherapist dyads and combined three components: habit‑forming functional exercise using the Lifestyle‑integrated Functional Exercise (LiFE) program; targeted home hazard reduction; and goal‑directed community mobility coaching. Importantly, the program was tailored to the participant’s level of stroke‑related disability, with the components prioritised according to mobility.
The fall rate was reduced by 33%(NOT GOOD ENOUGH!) in participants randomised to the FAST intervention compared with the group receiving usual care, and these changes were accompanied by clinically meaningful improvements in balance, walking speed, confidence and community participation.
Previous trials aimed at preventing falls after stroke have largely relied on conventional exercise programs or home modification alone, resulting in poor adherence and no significant reduction in falls. A systematic review and meta‑analysis of exercise-based programs showed a trend toward lower post-stroke fall rates compared with no or sham intervention, but estimates were imprecise, and effects varied. FAST showed the most robust reduction in falls, highlighting the trial’s importance and its capacity to transform the falls prevention landscape.
FAST addressed previous limitations by embedding balance challenging exercise into everyday activities, reframing exercise as a habit rather than homework; adherence was high, with more than 85% of participants completing all sessions.
The intervention was also pragmatic and relatively low cost, delivered through seven initial home visits, three booster visits and two phone calls over six months, using simple equipment and home modifications.
FAST Forward: from evidence to access
Health professionals need to be alert to the risk of falls when assessing and treating stroke survivors and ensure referrals are made to ongoing allied health support, prioritising evidence-based falls reduction programs like FAST.
Current Australian and New Zealand stroke guidelines do not yet include clear evidence for preventing falls after stroke, but this is likely to change given the strength of the FAST evidence. Guideline inclusion is essential to reposition falls prevention as a core component of long-term recovery rather than an optional add‑on.
However, providing access to effective falls prevention will require more than guideline endorsement. A Phase 4 implementation study is needed to facilitate widespread adoption into real world settings. Workforce upskilling for physiotherapists and occupational therapists in the FAST model of care will be a critical part. Training in the LiFE program and home hazard identification components are currently available. Further, the FAST study adaptations for stroke, collaborative approach, goal setting and resources will enable progression to implementation.
Conclusion
Falls after stroke are not an unavoidable consequence. High‑quality evidence now shows that a practical, home‑based intervention embedded in daily life can reduce falls and improve outcomes.
The question is no longer whether falls after stroke can be prevented, but whether we will act on the evidence to ensure stroke survivors have access to care that reduces avoidable harm and supports long‑term independence.
Associate Professor Katharine Scrivener is a physiotherapy clinician-researcher specialising in stroke rehabilitation at Macquarie and Monash Universities.
Dr Sally Day is an early career researcher and occupational therapy academic at the University of Sydney.
Professor Catherine Dean is a physiotherapist and leading stroke researcher and educator she is currently and Deputy Dean Education and Employability in the Faculty of Medicine Health and Human Sciences at Macquarie University.
Emeritus Professor Lindy Clemson is an occupational therapist from the University of Sydney and international research leader in falls prevention and public health research in ageing.
Professor Natasha A. Lannin is an occupational therapist clinician-researcher with a joint appointment at Bayside Health and Monash University, where she is the Head of the Brain Recovery and Rehabilitation Research group in the School of Translational Medicine.
Funding: The FAST trial was funded by the National Health and Medical Research Council, Australia (Project Grant #1157739). NL is supported by the Heart Foundation (Australia, grant #106762).
