For stroke prevention; for dementia prevention; for cognitive improvement; for cholesterol reduction; for plaque removal; for Parkinsons prevention; for inflammation reduction; for blood pressure reduction.
https://link.springer.com/article/10.1007/s12603-018-1095-4
Article
First Online: 13 August 2018
Abstract
Objective
To
systematically review evidence on the effects of nutrition therapy in
older stroke patients undergoing rehabilitation and identify its
effectiveness using meta-analysis.
Methods
PubMed
(MEDLINE), EMBASE (via Dialog), Cochrane Central Register of Controlled
Trial, World Health Organization International Clinical Trials Registry
Platform and Ichu-shi Web were searched for relevant articles.
Randomized controlled trials investigating the effects of nutrition
therapy compared to control interventions in older stroke patients
undergoing rehabilitation were considered eligible. The primary outcome
was activities of daily living (ADL), and secondary outcomes were
all-cause mortality, infections, pneumonia incidence, disability level,
walking ability, fall, stroke recurrence, and quality of life. The risk
of bias of each trial was assessed using the Cochrane Collaboration
Tool, and the quality of the body of evidence was assessed using the
Grading of Recommendations Assessment, Development and Evaluation
approach.
Results
Eight
randomized controlled trials with a total of 5484 participants were
included in the meta-analysis. The meta-analysis for ADL showed no
significant effects (mean difference, 4.16; 95% confidence interval
[CI], -0.88 to 9.20; I2=53%, low-quality evidence). The
meta-analyses for secondary outcomes revealed a significant effect of
reduced infections (risk ratio, 0.65; 95% CI, 0.51 to 0.84; I2=0%; low-quality evidence), with no significant effects on the other outcomes.
Conclusion
Nutrition
therapy had no statistically significant effect on ADL. However, it
reduced the incidence of infections. More high-quality trials are
warranted to clarify the effects of nutrition therapy in older stroke
patients undergoing rehabilitation.
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