Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, March 22, 2026

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

 I guess you incompetently don't know that reperfusion is only the first step in stroke recovery!  Where are the followup steps to 100% recovery? Haven't even thought of that? COMPLETE FUCKING INCOMPETENCY!

Optimizing Reperfusion to Improve Outcomes and Neurologic Function


ClinicalTrials.gov ID NCT06990867 Sponsor Corxel Pharmaceuticals Information Provided by Senior Director, Clinical Operations Study Start (Actual) 2025-05-15
Primary Completion (Estimated) 2029-10-31
Study Completion (Estimated)2029-12-31
Enrollment (Estimated)740
Study TypeInterventional
Last Update Posted2026-03-13

Study Overview

Brief Summary

The goal of this study is to evaluate the safety and efficacy of JX10 versus placebo in participants with Acute Ischemic Stroke (AIS) who present for care within 4.5 to 24 hours. The main question the study aims to answer are: 1. JX10 improves functional outcomes as measured by the modified Rankin Scale score when compared with placebo following AIS. 2. Risk of symptomatic intracranial hemorrhage of JX10 in participants with AIS. During Part 1, participants will be randomized to JX 10 (1mg/kg, 3 mg/kg) or placebo. During Part 2, participants will receive JX10 (optimal dose chosen from Part 1) or placebo. ClinicalTrials.gov Study Contact Name Corxel Pharmaceuticals Study Information Center Phone 201-268-3723

Study Contact Backup

NameNot available

PhoneNot available

United States Locations

California

Long Beach, California, United States 90806

Corxel Investigational Site

Sacramento, California, United States 95817

Corxel Investigational Site

Colorado

Colorado Springs, Colorado, United States 80909

Corxel Investigational Site

District of Columbia

Washington D.C., District of Columbia, United States 20007

Corxel Investigational Site

Florida

Delray Beach, Florida, United States 33484

Corxel Investigational Site

Illinois

Chicago, Illinois, United States 60616

Corxel Investigational Site

Kansas

Wichita, Kansas, United States 67214

Corxel Investigational Site

Maryland

Baltimore, Maryland, United States 21215

Corxel Investigational Site

Michigan

Kalamazoo, Michigan, United States 49048

Corxel Investigational Site

Traverse City, Michigan, United States 49684

Corxel Investigational Site

Missouri

St Louis, Missouri, United States 63110

Corxel Investigational Site

New York

Great Neck, New York, United States 11021

Corxel Investigational Site

New York, New York, United States 10029

Corxel Investigational Site

Ohio

Toledo, Ohio, United States 43606

Corxel Investigational Site

Oklahoma

Tulsa, Oklahoma, United States 74104

Corxel Investigational Site

Texas

Dallas, Texas, United States 75246

Corxel Investigational Site

Houston, Texas, United States 77030

Corxel Investigational Site

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