Deans' stroke musings: Robot-assisted upper limb training combined with Botulinum toxin injection in the treatment of upper limb spasticity: a randomised single-blinded controlled trial

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, July 26, 2020

Robot-assisted upper limb training combined with Botulinum toxin injection in the treatment of upper limb spasticity: a randomised single-blinded controlled trial

In multiple sclerosis so your doctor won't even think of trying to extrapolate this knowledge to stroke. If you have spasticity you are totally fucking screwed. I've had it for 14 years and it hasn't relented one bit. Fix my spasticity and I will easily recover my motor functions from dead areas.

Robot-assisted upper limb training combined with Botulinum toxin injection in the treatment of upper limb spasticity: a randomised single-blinded controlled trial

2019, Frontiers in Neurology

ORIGINAL RESEARCH
published: 24 October 2018doi: 10.3389/fneur.2018.00905Frontiers in Neurology | www.frontiersin.org
1
October 2018 | Volume 9 | Article 905
Edited by:
Giovanni Abbruzzese,Università di Genova, Italy
Reviewed by:
Paolo Tonin,Sant’Anna Institute, Italy Giovanni Morone,Fondazione Santa Lucia (IRCCS), Italy
*Correspondence:
Marialuisa Gandolﬁ marialuisa.gandolﬁ@univr.it
Specialty section:
This article was submitted toNeurorehabilitation, a section of the journal Frontiers in Neurology
Received:
03 August 2018
Accepted:
05 October 2018
Published:
24 October 2018
Citation:
Gandolﬁ M, Valè N, Dimitrova EK,Mazzoleni S, Battini E, Benedetti MD,Gajofatto A, Ferraro F, Castelli M,Camin M, Filippetti M, De Paoli C,Chemello E, Picelli A, Corradi J,Waldner A, Saltuari L and Smania N (2018) Effects of High-intensity Robot-assisted Hand Training onUpper Limb Recovery and Muscle Activity in Individuals With MultipleSclerosis: A Randomized, Controlled,Single-Blinded Trial.Front. Neurol. 9:905.doi: 10.3389/fneur.2018.00905
Effects of High-intensity Robot-assisted Hand Training onUpper Limb Recovery and Muscle Activity in Individuals With MultipleSclerosis: A Randomized, Controlled,Single-Blinded Trial
Marialuisa Gandolﬁ 1* ,

Nicola Valè 1 ,

Eleonora Kirilova Dimitrova 1 ,

Stefano Mazzoleni 2,

Elena Battini 2,

Maria Donata Benedetti 1,

Alberto Gajofatto 1,

Francesco Ferraro 3 ,

Matteo Castelli 4 ,

Maruo Camin 4,

Mirko Filippetti 1 ,

Carola De Paoli 1 ,

Elena Chemello 1,

Alessandro Picelli 1,5 ,

Jessica Corradi 1 ,

Andreas Waldner 6 ,

Leopold Saltuari 7,8

and Nicola Smania 1,5

1 Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy,
2 The BioRobotics Institute, Scuola Superiore Sant’ Anna, Polo Sant’ Anna Valdera, Pontedera, Italy,
3 Section of Neuromotor Rehabilitation,Department of Neuroscience, ASST Carlo Poma, Mantova, Italy,
4 Centro di riabilitazione Franca Martini—ATSM ONLUS,Trento, Italy,
5 UOC Neurorehabilitation, AOUI Verona, Verona, Italy,
6 Department of Neurological Rehabilitation, PrivateHospital Villa Melitta, Bolzano, Italy,
7 Research Department for Neurorehabilitation South Tyrol, Bolzano, Italy,
8Department of Neurology, Hochzirl Hospital, Zirl, Austria
Background:
Integration of robotics and upper limb rehabilitation in people with multiple sclerosis (PwMS) has rarely been investigated.
Objective:
To compare the effects of robot-assisted hand training against non-robotic hand training on upper limb activity in PwMS. To compare the training effects on hand dexterity, muscle activity, and upper limb dysfunction as measured with the International Classiﬁcation of Functioning.
Methods:
This single-blind, randomized, controlled trial involved 44 PwMS (Expanded Disability Status Scale:1.5–8) and hand dexterity deﬁcits. The experimental group (n =23) received robot assisted hand training; the control group(n=21) received nonrobotic hand training. Training protocols lasted for 5 weeks (50 min/session, 2 sessions/week).Before (T0), after (T1), and at 1 month follow-up (T2), a blinded rater evaluated patients using a comprehensive test battery. Primary outcome: Action Research Arm Test. Secondary outcomes: Nine Holes Peg Test; Fugl-Meyer Assessment Scale–upperextremity section; Motricity Index; Motor Activity Log; Multiple Sclerosis (MS) Quality of Life
−
54; Life Habits assessment—general short form and surface electromyography.
Results:
There were no signiﬁcant between-group differences in primary and secondary outcomes. Electromyography showed relevant changes providing evidence increased activity in the extensor carpi at T1 and T2