How will this change your competent? doctor's protocols that will prevent Parkinsons? Oh NO, your doctor HAS NOTHING! And the incompetent? board of directors hasn't fired them yet?
With your risk of Parkinsons post stroke, WHAT EXACTLY WILL YOUR DOCTOR DO TO PREVENT THIS?
Parkinson’s Disease May Have Link to Stroke March 2017
The latest here:
Researchers propose that Parkinson’s disease may start in the gut, not the brain
Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal barrier damage interact to ignite the biological cascade leading to neurodegeneration.
Environmental insults reduce gut resilience and initiate convergent mechanisms that drive Parkinson’s disease. A lifetime of environmental insults (including Western diets and food additives, nano- and microplastics, pesticides and herbicides, industrial solvents, and air pollution) act on the intestinal microbiome and barrier. These exposures promote microbiota dysbiosis, disrupt tight junctions, and erode the mucus layer, collectively reducing gut resilience. Once this peripheral defense is compromised, several mechanistic pathways propagate pathology to the brain: (a) amyloid seeding by bacterial functional amyloids, (b) maladaptive T cell education and autoimmune responses, (c) microbiome-driven metabolic shifts that generate neurotoxic metabolites and reduce short-chain fatty acids, and (d) systemic inflammatory amplification. Together, these processes lower the threshold for α-syn misfolding, neuroinflammation, and neurodegeneration.
A recent perspective published in the Journal of Clinical Investigation suggests that PD may, in some individuals, begin in the gut, driven by environmental exposures and changes in the microbiome.
No comments:
Post a Comment