Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, July 30, 2021

Study finds that cognitive activity in old age may delay the onset of dementia by 5 years

Well this gets you back to your starting point before stroke since you

have  5 lost years of brain cognition due to your stroke.

So your doctor is still responsible for having EXACT STROKE REHAB PROTOCOLS to recover those 5 lost years. Don't let her weasel out of it by quoting; 'All strokes are different, all stroke recoveries are different.' In my hospital that would be a fireable offense, it shows excuses are used to explain lack of job performance. If your doctors don't have 100% recovery protocols and are doing nothing to get there, that is also a fireable offense.There would be no excuses in my hospital, there should be none in yours.

  1. tPA full recovery better than 12%?

  2. Full stroke recovery better than 10%?

 If not, the whole hospital needs to be reconstituted. I take no prisoners in making stroke recovery better.


 Study finds that cognitive activity in old age may delay the onset of dementia by 5 years

– Yuji Sakai / DigitalVision / Getty Images

Dementia Comes 5 Years Later for Some (MedPage Today):A cognitively active lifestyle that involves reading and processing information in old age may delay the onset of dementia in Alzheimer’s disease by as much as 5 years, a longitudinal study suggested.

Older adults who had the highest level of late-life cognitive activity had a mean onset age of Alzheimer’s dementia of 94, reported Robert Wilson, PhD, of Rush University Medical Center in Chicago, and colleagues.

In contrast, those with the lowest late-life cognitive activity levels developed dementia at age 89, they wrote in Neurology.

Our study shows that people who engage in more cognitively stimulating activities may be delaying the age at which they develop dementia,” Wilson said in a statement.

It is important to note, after we accounted for late-life level of cognitive activity, neither education nor early-life cognitive activity were associated with the age at which a person developed Alzheimer’s dementia,” he continued. “Our research suggests that the link between cognitive activity and the age at which a person developed dementia is mainly driven by the activities you do later in life.”

This study provides further support for the concept of cognitive reserve, where genetic and life exposures allow some people to cope better than others with age- or disease-related brain changes,” noted Yaakov Stern, PhD, of Columbia University in New York City, who wasn’t involved with the research.

The Study:

Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia (Neurology). From the Abstract:

  • Objective: To test the hypothesis that higher level of cognitive activity predicts older age of dementia onset in Alzheimer’s disease (AD) dementia.
  • Methods: As part of a longitudinal cohort study, 1,903 older persons without dementia at enrollment reported their frequency of participation in cognitively stimulating activities. They had annual clinical evaluations to diagnose dementia and AD, and the deceased underwent neuropathologic examination. In analyses, we assessed the relation of baseline cognitive activity to age at diagnosis of incident AD dementia and to postmortem markers of AD and other dementias.
  • Results: During a mean of 6.8 years of follow-up, 457 individuals were diagnosed with incident AD at a mean age of 88.6 (SD = 6.4; range: 64.1–106.5). In an extended accelerated failure time model, higher level of baseline cognitive activity (mean 3.2, SD = 0.7) was associated with older age of AD dementia onset (estimate = 0.026; 95% confidence interval: 0.013. 0.039). Low cognitive activity (score = 2.1, 10th percentile) was associated with a mean onset age of 88.6 compared to a mean onset age of 93.6 associated with high cognitive activity (score = 4.0, 90th percentile). Results were comparable in subsequent analyses that adjusted for potentially confounding factors. In 695 participants who died and underwent a neuropathologic examination, cognitive activity was unrelated to postmortem markers of AD and other dementias.
  • Conclusion: A cognitively active lifestyle in old age may delay the onset of dementia in AD by as much as 5 years.

The Study in Context:

 
– Yuji Sakai / DigitalVision / Getty Images

Dementia Comes 5 Years Later for Some (MedPage Today):

A cognitively active lifestyle that involves reading and processing information in old age may delay the onset of dementia in Alzheimer’s disease by as much as 5 years, a longitudinal study suggested.

Older adults who had the highest level of late-life cognitive activity had a mean onset age of Alzheimer’s dementia of 94, reported Robert Wilson, PhD, of Rush University Medical Center in Chicago, and colleagues.

In contrast, those with the lowest late-life cognitive activity levels developed dementia at age 89, they wrote in Neurology.

Our study shows that people who engage in more cognitively stimulating activities may be delaying the age at which they develop dementia,” Wilson said in a statement.

It is important to note, after we accounted for late-life level of cognitive activity, neither education nor early-life cognitive activity were associated with the age at which a person developed Alzheimer’s dementia,” he continued. “Our research suggests that the link between cognitive activity and the age at which a person developed dementia is mainly driven by the activities you do later in life.”

This study provides further support for the concept of cognitive reserve, where genetic and life exposures allow some people to cope better than others with age- or disease-related brain changes,” noted Yaakov Stern, PhD, of Columbia University in New York City, who wasn’t involved with the research.

The Study:

Cognitive Activity and Onset Age of Incident Alzheimer Disease Dementia (Neurology). From the Abstract:

  • Objective: To test the hypothesis that higher level of cognitive activity predicts older age of dementia onset in Alzheimer’s disease (AD) dementia.
  • Methods: As part of a longitudinal cohort study, 1,903 older persons without dementia at enrollment reported their frequency of participation in cognitively stimulating activities. They had annual clinical evaluations to diagnose dementia and AD, and the deceased underwent neuropathologic examination. In analyses, we assessed the relation of baseline cognitive activity to age at diagnosis of incident AD dementia and to postmortem markers of AD and other dementias.
  • Results: During a mean of 6.8 years of follow-up, 457 individuals were diagnosed with incident AD at a mean age of 88.6 (SD = 6.4; range: 64.1–106.5). In an extended accelerated failure time model, higher level of baseline cognitive activity (mean 3.2, SD = 0.7) was associated with older age of AD dementia onset (estimate = 0.026; 95% confidence interval: 0.013. 0.039). Low cognitive activity (score = 2.1, 10th percentile) was associated with a mean onset age of 88.6 compared to a mean onset age of 93.6 associated with high cognitive activity (score = 4.0, 90th percentile). Results were comparable in subsequent analyses that adjusted for potentially confounding factors. In 695 participants who died and underwent a neuropathologic examination, cognitive activity was unrelated to postmortem markers of AD and other dementias.
  • Conclusion: A cognitively active lifestyle in old age may delay the onset of dementia in AD by as much as 5 years.

The Study in Context:

Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Study finds that cognitive activity in old age may delay the onset of dementia by 5 years
Study finds that cognitive activity in old age may delay the onset of dementia by 5 years

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