Deans' stroke musings: REVIEW OF CITICOLINE APPLICATION IN THE COMPLEX TREATMENT AND REHABILITATION OF PATIENTS WITH ACUTE ISCHEMIC STROKE

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, March 21, 2022

REVIEW OF CITICOLINE APPLICATION IN THE COMPLEX TREATMENT AND REHABILITATION OF PATIENTS WITH ACUTE ISCHEMIC STROKE

A Uzbekistan researcher puts together the closest thing I've seen to a protocol in over 10 years.

Of course I bet your doctor did nothing with citicoline when this Russian research came out in November 2019. So your doctor and hospital have been incompetent for a year and a half. Actually your board of directors is completely incompetent for not setting correct goals for the stroke department; 100% recovery protocols; all staff up-to-date on latest research provided by the research analyst who keeps track of such stuff and trains the staff in new research/protocols.

Neurometabolic therapy in the recovery period of ischemic stroke: impact on quality of life and cognitive functions November 2019

Diane wrote about Bob using CerAxon here. I'm sure your doctor doesn't read stroke survivor blogs either so would have missed this from April 2012.

REVIEW OF CITICOLINE APPLICATION IN THE COMPLEX TREATMENT AND REHABILITATION OF PATIENTS WITH ACUTE ISCHEMIC STROKE

Submission Date: February 19, 2022, Accepted Date: March 04, 2022, Published Date: March 14, 2022 Crossref doi: https://doi.org/10.37547/medical-fmspj-02-03-05

Sadriddin Sayfullaevich Pulatov Candidate of Medical Sciences, Associate Professor of the Department of Rehabilitation,sports medicine and physical education Bukhara State Medical Institute, Uzbekistan

ABSTRACT

The review is devoted to the citicoline application in the complex treatment and rehabilitation of patients with acute ischemic stroke. The results of numerous experimental and clinical studies of the effect of citicoline on ischemia and hypoxia of the brain are presented. The basic pharmacological properties of citicoline, which has a complex neuroprotective effect are highlighted. Data are presented on the latest multicenter placebo-controlled trials of the drug in acute stroke. The basic principles of successful neurorehabilitation in stroke are discussed: early onset, continuity, continuity, multidisciplinary organizational approach, combination of rehabilitation measures and medication support of neuroplasticity [4,6].

This paragraph from there is the most important:

The review articles provide data on the optimal dosing regimen based on the results of clinical trials of the drug. So citicoline, administered at a dose of 1000 mg/day for 8 weeks, accelerated regression of hemiplegia, intravenous administration of the drug at a dose of 750 mg/day for 10 days, starting from the first 48 hours after the appearance of symptoms of stroke, contributed to the restoration of motor and cognitive functions, with intravenous administration of 1 g for 14 days marked by more rapid recovery of consciousness, a significant improvement in general condition and functional status. It is noted that a relatively high functional status was achieved in 61.3% of those who took citicoline at a dose of 500 mg/day, 39.4% of those who took citicoline at a dose of 1000 mg/day, and 52.3% of those who took citicoline at a dose of 2000 mg/day. The degree of improvement in the groups receiving citicoline at a dose of 500 and 2000 mg/day was approximately the same.