Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, May 2, 2024

Global, regional, and national burden of stroke from 1990 to 2019: A temporal trend analysis based on the Global Burden of Disease Study 2019

 But you tell us NOTHING ON 100% RECOVERY RESULTS!  The only goal in stroke, I guess that won't be important to you until you are the 1 in 4 per WHO that has a stroke Might be too late then for you to solve the 100% problem!

So no reporting or measurement of 100% recovery, obviously not important to the medical staff or researchers. But vastly important to stroke survivors. 

“What's measured, improves.” So said management legend and author Peter F. Drucker 

Global, regional, and national burden of stroke from 1990 to 2019: A temporal trend analysis based on the Global Burden of Disease Study 2019

Abstract

Background:

Stroke is the second leading cause of death and the leading cause of disability worldwide. However, how the prevalence of stroke varies across the world is uncertain.

Aims:

The aim of this study was to analyze temporal trends of prevalence for stroke, including ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) at the global, regional, and national levels.

Methods:

The age-standardized prevalence rates (ASPR) of stroke, IS, ICH, and SAH, along with their corresponding 95% uncertainty intervals (UI), were derived from data in the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This provides estimates for the burden of 369 diseases and injuries globally in 2019, as well as their temporal trends over the past 30 years. Joinpoint regression analysis was used to analyze the 1990–2019 temporal trends by calculating the annual percentage change (APC) and average annual percentage change (AAPC), as well as their 95% confidence interval (CI).

Results:

In 2019, the global ASPR of stroke was 1240.263 per 100,000 population (95% UI: 1139.711 to 1352.987), with ASPRs generally lower in Europe compared to other regions. Over the period from 1990 to 2019, a significant global decrease in ASPR was observed for stroke (AAPC −0.200, 95% CI: −0.215 to −0.183), IS (AAPC −0.059%, 95% CI: −0.077 to −0.043), SAH (AAPC −0.476, 95% CI: −0.483 to −0.469), and ICH (AAPC −0.626, 95% CI: −0.642 to −0.611). The trends of ASPR of stroke, IS, SAH, and ICH varied significantly across 204 countries and territories.

Conclusion:

Our findings highlight significant global disparities in stroke prevalence, emphasizing the need for ongoing monitoring and intensified efforts in developing regions to reduce the global burden of stroke.

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Discover the Latest Cutting Edge Advancements in Stroke Care: The Supernova Revascularization Device & The Neutron Aspiration Catheter

Anytime I see 'care' in any stroke press release I know the stroke medical world is not willing to disclose actual results because they are so fucking bad, it wouldn't look good, so misdirection is used. Don't fall for that misdirection! By touting 'care' they are not telling you about results or recovery which survivors want! Survivors don't care about door to needle time; you FUCKING BLITHERING IDIOTS; they want 100% recovery! Why aren't you providing that?

Big fucking whoopee.

 

 But you tell us NOTHING ABOUT RESULTS. They remind us they 'care' about us multiple times but never tell us how many 100% recovered.  You have to ask yourself why they are hiding their incompetency by not disclosing recovery results.  ARE THEY THAT FUCKING BAD?


Three measurements will tell me if the stroke medical world is possibly not completely incompetent; DO YOU MEASURE ANYTHING?  I would start cleaning the hospitals by firing the board of directors, you can't let incompetency continue for years at a time.

There is no quality here if you don't measure the right things.

  1. tPA full recovery? Better than 12%?
  2. 30 day deaths? Better than competitors?
  3. rehab full recovery? Better than 10%?

 

You'll want to know results so call that company president(whomever that is) RESULTS are; tPA efficacy, 30 day deaths, 100% recovery. Because there is no point in using this if they are not willing to publish results.

In my opinion this partnership allows stroke hospitals to continue with their tyranny of low expectations and justify their complete failure to get survivors 100% recovered. Prove me wrong, I dare you in my stroke addled mind. If your stroke hospital goal is not 100% recovery you don't have a functioning stroke hospital.

 

All you ever get from hospitals are that they are following guidelines; these are way too static to be of any use. With thousands of pieces of stroke research yearly it would take a Ph.D. level research analyst to keep up, create protocols, and train the doctors and therapists in their use. 

If your stroke hospital doesn't have that, you don't have a well functioning stroke hospital, you have a dinosaur. 

 Survivors want RECOVERY not 'care'

“What's measured, improves.” So said management legend and author Peter F. Drucker 

The latest invalid chest thumping here:

Discover the Latest Cutting Edge Advancements in Stroke Care: The Supernova Revascularization Device & The Neutron Aspiration Catheter

Join us on May 3rd for an exciting launch event exploring the latest advancements in stroke care: The Supernova Revascularization Device & The Neutron Aspiration Catheter Morning Virtual Panel | Afternoon On-Site Hands-On Workshop led by leading experts in the field:


 

 

 

 

 

 

 

 

 

Ashutosh Jadhav Tudor Jovin Dileep R. Yavagal, MD Naoki Kaneko Albert Yoo Fazal Zaidi Kunakorn Atchaneeyasakul, MD MPH Nicholas Liaw #GlobalStroke #Thrombectomy #Innnovation #GravityMission

Wednesday, May 1, 2024

When should physicians start thinking about medical cannabis for patients?

 Didn't your competent? doctor start prescribing it years ago?

Well, this cartoon says it all, your doctor will never prescribe medical marijuana.. 

 

 

 

 

 

 

 

 

 

 

 

 

 

I'm doing it after my next stroke.

My 13 reasons for marijuana use post-stroke.  

Don't follow me, I'm not medically trained and I don't have a Dr. in front of my name.

When should physicians start thinking about medical cannabis for patients?

Key takeaways:

  • Cannabis may alleviate neuropathic pain, chemotherapy-induced nausea/vomiting and MS-associated spasticity.
  • The studies, however, are generally of low quality, a speaker said.

BOSTON — There is some evidence that cannabinoids may help with neuropathic pain, chemotherapy-induced nausea/vomiting and MS-associated spasticity, “but it’s not exactly a slam dunk,” a speaker said.

Most of the evidence on the health effects of cannabinoids comes from trials outside the United States and often involves synthetic forms “that may or may not have any similarity to what our patients get when they go to a dispensary,” Ellie Grossman, MD, MPH, an instructor in the division of internal medicine at Harvard Medical School and Cambridge Health Alliance, said during a presentation at the ACP Internal Medicine Meeting. In addition, studies typically involve self-reports, and patients may not know how much chemical they are ingesting.

Ellie Grossman, MD, MPH

Despite these limitations, Grossman told attendees that “if you’re going to leave here with anything today, you can remember there are three indications for which there is some evidence in favor of cannabinoid effectiveness.”

‘Some signal for helpfulness’

“By far” the most common medical condition that cannabinoids are used for is chronic pain, Grossman said. It is also one of the more commonly studied medical conditions in cannabis trials, particularly neuropathic pain.

A meta-analysis from 2015 showed that cannabinoids reduced chronic pain, although “the effect size is not huge,” Grossman said.

“If you look at the size of those studies, they are all individually small [and] they are generally low-quality studies. But there is this thrust of evidence showing an effect,” she said.

There are essentially no data comparing cannabinoids with other pain agents, Grossman noted. Most of the trials are older and used pain scores as the primary outcome. Since then, researchers determined that functional outcomes are a better marker. So, there is “almost no evidence to guide us” on those clinically important outcomes, Grossman said.

“Garbage in, garbage out,” she added.

The Agency for Healthcare Research and Quality is conducting a living systematic review that is updated every quarter. The most recent review from January found that one product — a THC:CBD oromucosal spray that is not available in the U.S. — appears to have a beneficial effect on chronic pain with moderate evidence. All the other cannabis products studied either had no evidence or low-quality evidence.

A Cochrane review restricted to neuropathic pain identified 16 studies with 1,750 participants. These studies showed a moderate effect, but the quality was very low, and twice as many patients in the cannabis arms dropped out because of adverse events, Grossman said.

“There is some signal for helpfulness for cannabinoid, but it’s messy,” she said.

The two other indications with data supporting the use of cannabinoids are chemotherapy-induced nausea/vomiting and MS-associated spasticity. Like chronic pain, however, the evidence is “not great quality,” Grossman said. For chemotherapy-induced nausea/vomiting, some studies demonstrated an improvement compared with placebo, but there are no data comparing cannabinoids with other antiemetics. For spasticity, there appears to be an improvement in patient-related outcomes, but the evidence on clinician-reported outcomes is unclear, according to Grossman.

There is less robust or negative evidence of cannabinoids for:

  • weight loss/anorexia in HIV;
  • sleep disorders and anxiety;
  • glaucoma;
  • Tourette’s syndrome;
  • inflammatory bowel disease; and
  • PTSD.

Adverse effects

In studies of patients who used cannabinoids medicinally, Grossman said short-term adverse effects included sedation, “feeling high,” dizziness, speech disorders, muscle twitching, hypertension, numbness, psychiatric effects, euphoria, dysphoria, impaired memory and disassociation.

“There are a whole lot of questions about longer term health care risks,” she said. “All the evidence comes from studies of people who have been using it for recreational reasons.”

When inhaled or smoked, cannabinoids are associated with an increased risk for coughing, wheezing and sputum/phlegm, according to Grossman.

When used during pregnancy, there is an increased risk for lower neonatal birth weight and preterm labor.

Additionally, there is emerging evidence linking cannabis to myocardial infarction, stroke, COPD and mortality.

“The signals keep coming, in particular about cardiovascular disease,” Grossman said.

Other longer term risks of cannabinoids include the development of psychotic symptoms, psychosis relapse, suicide and cannabis use disorder. In a study published in JAMA Network Open in 2023, 13% of participants who used cannabis for medical purposes met the criteria for cannabis use disorder. Among them, 1.3% met criteria for moderate to severe cannabis use disorder.

When weighing the benefits and risks of cannabinoids, Grossman pointed attendees to a clinical practice guideline developed by Canadian researchers.

According to the guideline:

  • In order to achieve a 30% or greater reduction in chronic pain, the number of patients needed to treat is 11 and the number needed to harm is six.
  • To control chemotherapy-induced nausea/vomiting, the number needed to treat is three and the number needed to harm is six.
  • For a 30% or greater improvement in spasticity, the number needed to treat is 10 and the number needed to harm is six.

“How we weigh that in our individual patients, I leave up to you,” Grossman said. “That is one way of thinking about this.”

References:

Sources/Disclosures

Collapse

Source:

Grossman E. Cannabinoids for clinical care: What prescribers need to know. Presented at: ACP Internal Medicine Meeting; April 18-20, 2024; Boston.

Our General Election Manifesto Make Stroke a Priority UK

With just this manifesto and NO strategy outlined on how to get to 100% recovery, this will be ignored for the useless crapola it is!

 You could vastly reduce disability and deaths by having 100% recovery protocols!  Getting people directly back to their old life. But it will require destroying the existing stroke associations since they don't know what the fuck they are doing as proven by this 'manifesto'!

Our General Election Manifesto Make Stroke a Priority UK

Stroke is the UK's fourth biggest killer and a leading cause of disability. The good news is that with the right investment, stroke is preventable, treatable, and recoverable. Ahead of the General Election, we have set out what needs to change to improve stroke care.

Read about how the next UK Government can make this happen and what you can do to help.

Nationwide, 6 stroke advocates selected to receive 2024 Stroke Hero Awards

 So rather than actually solving stroke the ASA lazily recognizes people they should have helped to fully recover by sponsoring research that gets survivors recovered!. They need to be destroyed and run by survivors, that is the only way stroke will ever get solved.

Nationwide, 6 stroke advocates selected to receive 2024 Stroke Hero Awards

The American Stroke Association spotlights the resiliency of local individuals and groups in the fight against stroke
 DALLAS, May 1, 2024 Each year, approximately 800,000 people in the U.S. have a stroke.[1] Six local stroke heroes from across the country are being recognized by the American Stroke Association, a division of the American Heart Association, for their resiliency and dedication in the fight against stroke.

The American Stroke Association’s annual Stroke Hero Awards honors stroke survivors, health care professionals, advocates and caregivers. During May, American Stroke Month, the Association, devoted to a world of healthier lives for all and celebrating 100 years of lifesaving service, honors these Stroke Heroes and proudly advocates(Advocating DOES NOTHING TO GET SURVIVORS RECOVERED YOU BLITHERING IDIOTS!) for stroke survivors year-round. Those who have had a stroke often must work against physical, emotional and cognitive changes to move forward. The following Stroke Heroes are being recognized for outstanding efforts in educating, inspiring and raising awareness about stroke.

Send me hate mail on this: oc1dean@gmail.com. I'll print your complete statement with your name and my response in my blog. Or are you afraid to engage with my stroke-addled mind?  Survivors would like to know why you are being so fucking incompetent!

Oops, I'm not playing by the polite rules of Dale Carnegie,  'How to Win Friends and Influence People'. 

Telling supposedly smart stroke medical persons they know nothing about stroke is a no-no even if it is true. 

Politeness will never solve anything in stroke. Yes, I'm a bomb thrower and proud of it. Someday a stroke 'leader' will try to ream me out for making them look bad by being truthful, I look forward to that day.

 

 

Winners include:

  • Caregiver Hero: Loretta Sharp Gray, Oakwood Village, Ohio
    • Loretta Sharp Gray went from teaching students with disabilities to personal caregiver for her life partner, who survived a serious stroke and wasn’t expected to live. Never complaining or seeking recognition, she takes care of him at home with periodic home visits from his primary care doctor and nurse practitioner. At the same time, this grandmother is an advocate, volunteer and trusted messenger in the community. She also volunteers with the Association’s STEM Goes Red program. Students from local schools learn about heart health, stroke and CPR, as well as careers in science, technology, engineering and math.
  • Equity Hero: Dr. Kimon Bekelis, Babylon, New York
    • Kimon Bekelis, MD has worked tirelessly to ensure equal access to lifesaving stroke care on Long Island, N.Y. regardless of demographics or ability to pay. He led the development of the Stroke and Brain Aneurysm Center at Good Samaritan, the first Comprehensive Stroke Center on the south shore of Long Island, expanding access to high-quality stroke care for an underserved population. He believes everyone deserves an equal chance at the best possible outcome. Throughout his career, Dr. Bekelis has embodied this commitment to health equity and worked to enact meaningful improvements in equitable access to lifesaving stroke care.
  • Group Heroes: Centre for Neuro Skills, various locations in California and Texas
    • For more than 40 years, the Centre for Neuro Skills has provided community-based treatment for people recovering from brain injuries. As a recognized leader in the stroke and brain injury rehabilitation field, the Centre’s specially trained staff offer outcome-driven medical treatment, therapeutic rehabilitation and disease management services. The Centre lends its clinical expertise for educational interviews and shares inspiring stroke patient stories to local and national media for national recognition days, such as World Stroke Day and American Stroke Month, to educate the public about stroke prevention, causes and rehabilitation.
  • Pediatric Hero: Reegan Lueken, Ely, Iowa
    • After a stroke at age 12, Reegan Lueken's perseverance is an inspiration. Returning home from the hospital wasn’t the end of her journey. She participated in intensive therapies to help get her life back on track. Now a 10th grader, her stroke has taught her that every day is a gift. Reegan has worked hard to be on the honor roll and complete her first community college course. She uses the Association’s platform to share her story so others can learn from her experience. She and her mom, a heart disease survivor, want others to know that a stroke can happen to anyone at any age.
  • Survivor Hero: Craig Northcutt, Durant, Oklahoma
    • Craig Northcutt nearly lost his life in an ATV accident, leaving him with a brain bleed that caused a stroke. After months of intensive neurorehabilitation, he relearned how to walk, talk and return to work. Now he raises awareness about stroke through professional mentorship and by sharing his story with high school students and stroke survivors. Craig is celebrating his 12-year stroke anniversary and his 30-year work anniversary with the Choctaw Nation. As part of the organization’s Tribal Advocacy program, he helps tribal nation members develop their professional skills and find jobs.
  • Voters’ Choice Hero: Rick Hoeg, Northville, Michigan
    • ​​After having a stroke on Dec. 30, 2022, Rick Hoeg tackled the hardest challenge of his life: recovery. While still in aggressive outpatient rehab, Rick created a nine-part YouTube series on stroke education and prevention, often featuring his rehabilitation therapists. In his series, he taught stroke warning signs and shared his recovery journey, reaching over 100,000 viewers. Rick’s video series culminated in a $30,000 fundraiser benefiting the hospitals that saved his life. Today, he continues to educate about stroke and supports hospital staff in their vital work.

Winners were selected by a nationwide panel of volunteer judges from the American Stroke Association, with the exception of the Voters’ Choice Award, which was selected via online popular vote.

For more information, visit Stroke.org/HeroAwards.

New research to help strengthen our understanding of stroke recovery

 If they are not going back to the start of the stroke and stopping the 5 causes of the neuronal cascade of death in the first week thus saving millions to billions of neurons, well then they are not going back and solving the original cause of the movement problem; DEAD NEURONS! Which means their mentors and senior researchers don't know what the hell they are doing! Rehab after the stroke barely works; Only 10%? fully recover!

New research to help strengthen our understanding of stroke recovery

University of Northampton academics are looking to improve movement and flexibility for people who have had a stroke.

Helping lighten the load so stroke patients get back on their feet forms new research from University of Northampton (UON).

A stroke is a serious life-threatening medical condition that happens when the blood supply to part of the brain is cut off.


The prevalence of strokes in the UK is expected to increase from 950,000 people in 2015 to 2.1 million in 2035, an increase of 120%. The cost associated with strokes in 2015 was £26 billion, which is expected to increase to £75 billion in 2035, an increase of 194%.

Brett Baxter and University of Northampton students
Brett Baxter and University of Northampton students

Physical rehabilitation work to help stroke patients return to ‘normal’ life usually focusing attention on the affected side of their body with muscle growing exercises.

Now, UON academics are investigating how stroke patients’ muscles on the affected side of their bodies improve, with no exercises, when a different muscle activity is used on the other side.

When we train our bodies – such as lifting weights at the gym – the other, untrained side benefits because of the cross-educational effect: the muscles not being trained adapt and show signs of improvements anyway.

Exercising the good side to recover the 'bad' side. December 2012)

 So you're doing something that has been proven for over a decade already! WHY? Your mentors and senior  researchers are so out-of-date, they don't even know of previous research in their field? In my opinion; complete incompetence!


With this, our muscles become stronger due to neurological adaptations although this phenomenon is usually observed in traditional resistance training (such as lifting and lowering a weight).

However, during eccentric muscle contractions when the muscles become longer this cross-educational effect is more pronounced. With this research, UON academics will focus on how this can help people who have suffered a stroke.

Brett Baxter, Lecturer in Sport & Exercise Science, is working on research with colleagues in Sport and Physiotherapy. He says: “Strokes can have a devastating impact on people’s health and wellbeing, compromising their quality of life and autonomy.

“Traditional stroke rehabilitation places, understandably, a focus on techniques on the affected side of the body. This can be gruelling and challenging, but what we’re exploring with this research is a novel approach that could have huge implications by changing the narrative of stroke rehabilitation efforts.”


The research will take place over the summer, starting with a briefing session for interested volunteers and to assess their eligibility to take part. If eligible, on the same day volunteers will perform the exercise so the team can check what is the right resistance for the exercise to hit the right intensity and assess their response.

Volunteers will be invited back at a later date for one more session to perform five sets of the exercise at the chosen intensity.

Brett concludes: “As people who have had a stroke are at an increased risk of another, we will perform the pilot tests under safe conditions to check participants’ health and the feasibility of the training by monitoring beat-to-beat heart rate and blood pressure and terminating the test if these raise to an excessively elevated level or upon the participant’s request”.

“We also want this research to be co-created with our volunteers so their thoughts on what we are doing will be crucial to taking the pilot forward. For anyone who wishes to take part in the briefing session and the later stages of the research, please email me for further details.”

Route 92 announces US FDA 510(k) clearance for FreeClimb 54 reperfusion system

 Does your competent? stroke hospital have procedures in place to bring in new stroke interventions? NO? So you don't have a functioning stroke hospital?  You'll have to direct the ambulance to a more successful place.

Route 92 announces US FDA 510(k) clearance for FreeClimb 54 reperfusion system

Route 92 Medical has today announced receipt of US Food and Drug Administration (FDA) 510(k) clearance for the FreeClimb 54 reperfusion system, comprised of the FreeClimb 54 aspiration catheter paired with a Tenzing 5 delivery catheter.

This new system is part of a growing portfolio of neurovascular devices from Route 92, designed to work harmoniously as a complete endovascular thrombectomy solution to address a broad range of neurovascular interventions, according to a company press release.

“Route 92 Medical works to provide innovative endovascular thrombectomy solutions to clinicians, helping them maximise their opportunity to restore blood flow to the brain on their first attempt,” said Tony Chou, chief executive officer of Route 92. “The FreeClimb 54 reperfusion system is an essential addition to our product portfolio, enabling clinicians to use our products to address a wider range of patient needs.”

The FreeClimb 54 system can telescope through the company’s complementary products, allowing physicians to rapidly, predictably reach and remove stroke-causing clots during endovascular thrombectomy procedures. Route 92’s recent press release also notes that FreeClimb 54’s robust tip and shaft design facilitates use for multiple passes, and compatibility with other technologies. Additionally, the system may be used to remove distal clots when first-line therapies fail to completely remove the clot.

“The launch of the FreeClimb 54 reperfusion system continues Route 92 Medical’s progressive and complete approach to stroke care,” stated Peter Pema (Riverside Methodist Hospital, Columbus, USA). “This system combines the unparalleled effectiveness and safety of their Tenzing delivery system with an aspiration catheter that can reach far into the cerebral circulation beyond the proximal branch vessels. Thus, the size of the FreeClimb 54 system offers clear advantages to clinicians looking to achieve rapid, safe recanalisation of vessels on the first attempt.”

“The FreeClimb 54 system is a gamechanger,” added Ronald Budzik (Riverside Methodist Hospital, Columbus, USA). “It is a simple system capable of getting a larger bore aspiration catheter to distal anatomy, especially around tighter turns.”

Utility and usability of a wearable system and progressive-challenge cued exercise program for encouraging use of the more involved arm at-home after stroke—a feasibility study with case reports

 This obviously was tried on high functioning individuals. Nobody like me with spasticity that prevents voluntary movement. So going against the precept of 'Leave no survivor behind!'

Utility and usability of a wearable system and progressive-challenge cued exercise program for encouraging use of the more involved arm at-home after stroke—a feasibility study with case reports

Abstract

Background

Understanding the role of adherence to home exercise programs for survivors of stroke is critical to ensure patients perform prescribed exercises and maximize effectiveness of recovery.

Methods

Survivors of hemiparetic stroke with impaired motor function were recruited into a 7-day study designed to test the utility and usability of a low-cost wearable system and progressive-challenge cued exercise program for encouraging graded-challenge exercise at-home. The wearable system comprised two wrist-worn MetaMotionR+ activity monitors and a custom smartphone app. The progressive-challenge cued exercise program included high-intensity activities (one repetition every 30 s) dosed at 1.5 h per day, embedded within 8 h of passive activity monitoring per day. Utility was assessed using measures of system uptime and cue response rate. Usability and user experience were assessed using well-validated quantitative surveys of system usability and user experience. Self-efficacy was assessed at the end of each day on a visual analog scale that ranged from 0 to 100.

Results

The system and exercise program had objective utility: system uptime was 92 ± 6.9% of intended hours and the rate of successful cue delivery was 99 ± 2.7%. The system and program also were effective in motivating cued exercise: activity was detected within 5-s of the cue 98 ± 3.1% of the time. As shown via two case studies, accelerometry data can accurately reflect graded-challenge exercise instructions and reveal differentiable activity levels across exercise stages. User experience surveys indicated positive overall usability in the home settings, strong levels of personal motivation to use the system, and high degrees of satisfaction with the devices and provided training. Self-efficacy assessments indicated a strong perception of proficiency across participants (95 ± 5.0).

Conclusions

This study demonstrates that a low-cost wearable system providing frequent haptic cues to encourage graded-challenge exercise after stroke can have utility and can provide an overall positive user experience in home settings. The study also demonstrates how combining a graded exercise program with all-day activity monitoring can provide insight into the potential for wearable systems to assess adherence to—and effectiveness of—home-based exercise programs on an individualized basis.

Background

Stroke is a leading cause of disability and a growing public health concern. Approximately 9.4 million Americans had a stroke between 2017 and 2020 (an overall prevalence of 3.3%, which is expected to increase to nearly 4% by 2030) [1]. An increasing population of individuals surviving stroke poses a significant burden on social, economic, and health care systems because motor impairments that limit movement on one side of the body affect up to 80% of survivors [2]. Motor impairments significantly degrade quality of life by hindering activities of daily living and limiting community participation. Deficits in motor function often result from physical impairment, but can also arise from the behavioral phenomenon of learned nonuse whereby limb use is suppressed despite sufficient motor capacity [3]. Prolonged nonuse can lead to weakness and contractures that further exacerbate impairment. Therefore, a primary goal of rehabilitation after stroke focuses on promoting recovery of impaired movements. Exercise training is an effective tool in restoring motor function, even beyond the acute stage of recovery wherein most of the practical gains are typically seen [4, 5].

Although physical and occupational therapists commonly prescribe home exercise programs to manage residual sensorimotor deficits after stroke, adherence rates can be low thereby limiting the patient’s potential recovery [6, 7]. Home-based tele-rehabilitation programs with therapists providing intermittent supervision of the patient may help mitigate adherence issues [7] and demonstrate potential functional benefits [8, 9] that equal or exceed those provided by conventional face-to-face therapy (for reviews see [10, 11]). Augmenting home-based tele-rehabilitation programs with wearable technologies that monitor movement and provide feedback to patients and therapists has potential to improve stroke outcomes through increased intensity of therapy and adherence to rehabilitation programs [12, 13]; see also [9]. Despite its promise, wearable activity monitoring technology is not widely used by therapists in day-to-day stroke care in the clinic [14] or by patients at home. Barriers to adoption include lack of skills and knowledge of patients, not knowing what brand and type of monitor to choose (cf. [15]), and the skills, beliefs, and attitudes of individual therapists, which determine the current use of wearable technology [14]. Other factors, including user motivation and trust in the technology likely contribute to patterns of low adherence (cf. [16, 17]).

In recognition of this opportunity, there has been a recent explosion in the number and types of technologies proposed to promote adherence to home-based exercise programs for physical rehabilitation after stroke [18,19,20,21,22,23,24,25,26,27,28,29], for reviews see [30,31,32]. Most of these systems use micro-electro-mechanical sensor (MEMS) technology such as accelerometers and gyroscopes to monitor body movements in real-time and to derive summary statistics such as “activity counts” [22, 33, 34] or measures of movement smoothness [23]. Other approaches to motion tracking are possible such as visual image processing systems cf. [35] but lack the portability and convenience of wearable systems.

The most common application of wearable technologies is the monitoring and assessment of the quantity and quality of movement [18, 26, 36,37,38,39,40]. Wearable technologies can also provide helpful cues (i.e., reminders, nudges) to perform activities such as exercises prescribed as therapy [19, 20, 24, 25, 27, 28, 41]. In one exemplar study, Holden and colleagues describe a wrist-worn system [24] that provided a vibratory stimulus to the more-involved arm when that arm’s activity level fell below a personalized threshold for a selected time window. If prompted, the participant was instructed to increase more-involved arm movements, ideally by performing pre-selected activities from a self-directed repetitive functional task practice program [19]. The study protocol also included twice weekly meetings with a study therapist to download acceleration data and to provide performance feedback to the participant. Across seven participants and the 4-week program, this system provided only a small number of cues per day (median = 4), although mean arm activity increased following prompts by 11% to 29%. The authors conclude that personalized prompts delivered by a wrist-worn accelerometer may enhance self-directed arm activity after stroke [19]. However, for technologies to be adopted by clinicians and their patients, the systems must not only have practical utility, but they must also provide a positive user experience within the context of their intended use scenarios cf. [20, 27, 29].

To date, wearable rehabilitation exercise systems have prompted users to increase activity relatively infrequently, such as once every 10 min [25], once an hour [24] or less frequently [24, 27]. User feedback indicates that they desire flexible exercise schedules and well-defined exercise recommendations with graded challenge levels based on ability [27]. In the current study, we sought to assess the utility, usability, and user experience of a wearable exercise cueing and monitoring system designed to promote high-dose (60 cues per 30-min exercise session, 3× per day), graded-challenge exercise at-home with a small cohort of hemiparetic stroke survivors. Our clinician-designed exercise program was motivated by the fact that many survivors of stroke are ineligible for interventions such as constraint-induced movement therapy (CIMT) [42, 43], which is suitable only for participants retaining substantial motor capacity (e.g., residual wrist extension). Our novel exercise program seeks to engage patients in high-dose activities while accepting of a broad range of impairment levels, ranging from an inability to move the more-involved arm and hand to the ability to move that limb independently. Our study included a wide age range of participants (29 to 63 years old), a wide range of time post-stroke (2 to 21 years), and varying living situations (i.e., living alone, living with family, or in assisted care settings) to demonstrate how such a system can be used by different populations. Quantitative movement data was derived from motion trackers worn on both wrists. End-user feedback was collected through well-validated quantitative surveys that assess key aspects of the subjective user experience. Additional qualitative feedback was collected through questionnaires and informal discussions designed to solicit recommendations for future system modifications or improvements. After summarizing our findings, we provide two individual case reports that demonstrate how patients with different levels of residual motor capacity chose to engage with the cued exercise program in their home setting.

This Is The Powerful Impact Food Has On Your Brain Health by Debbie Hampton

 You'll want your competent? doctor to have the nutritionist and dietician create diet protocols with this in mind, along with all these other needs!

For dementia prevention; for cognitive improvement; for cholesterol reduction; for plaque removal; for Parkinsons prevention; for inflammation reduction; etc.

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This Is The Powerful Impact Food Has On Your Brain Health by Debbie Hampton

A couple important paragraphs here:

The study showed that people with a healthy balanced diet had better brain health, cognitive function and mental health than others. We compared the balanced diet to three other diet groups — low-carb (18%), vegetarian (6%) and high protein/low fibre (19%). We found that people who ate a more balanced diet had better:

  1. fluid intelligence (the ability to solve new problems),
  2. processing speed, memory and
  3. executive functions (a set of mental skills that include flexible thinking and self-control)

than the other diets. This also corresponded to better brain health — with higher grey matter volumes (the outermost layer of the brain) and better structured neurons (brain cells), which are key markers of brain health.