Your Brain Needs Cholesterol - David Perlmutter M.D.
Cholesterol could cause dementia, research warns.
Scientists found a link between the fatty substance in the blood and amyloid-beta protein — a key player in the onset of Alzheimer’s disease.
They discovered that cholesterol in the brain is a trigger for the formation of clusters of amyloid-beta. They eventually lead to the formation of amyloid plaques in a toxic chain reaction that results in the death of brain cells.
An international team led by Cambridge University researchers said the identification of a new “pathway” in the brain where amyloid-beta sticks together, or aggregates, could represent a fresh target for potential treatments.
“We’re not saying that cholesterol is the only trigger for the aggregation process, but it’s certainly one of them.”
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