Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, June 7, 2021

'Landmark study delivers major stroke prevention breakthrough' - MRINZ

 You may want this test so if found your doctor can implement the protocols that will prevent this stroke. YOUR DOCTOR'S RESPONSIBILITY.

'Landmark study delivers major stroke prevention breakthrough' - MRINZ 

A simple procedure, taking six minutes on average, and performed at the same time as other heart surgery, reduces the risk of stroke by about one third in high-risk patients with atrial fibrillation, according to results of the recently published ‘Left Atrial Appendage Occlusion Study III’ (LAAOS III).

New Zealand trial lead Dr Shay McGuinness, Medical Research Institute of New Zealand (MRINZ) Senior Clinical Research Fellow, was the principal investigator for the Auckland District Health Board LAAOS III trial site, co-authoring the study alongside international contemporaries.

Atrial fibrillation (AF) is a common medical condition where the upper chambers of the heart do not always beat in a coordinated way with the lower chambers. People can experience palpitations when this happens, and in a certain part of the heart - the left atrial appendage - this can lead to blood becoming stagnant and forming clots. These clots are at risk of dislodging and being pumped into the brain, where they can block blood vessels to cause a stroke. The clots also risk being pumped into other parts of the body, where they can cause trouble by cutting off blood supply.

The left atrial appendage can be surgically 'blocked off', known as occlusion, in several ways to prevent clot formation, theoretically preventing this kind of stroke in patients with AF. However, until now, there has been no definitive evidence to prove whether this is effective.

129 patients from Auckland, Waikato and Wellington Hospitals contributed to this large international study, which included 4770 participants, across 105 centres, in 27 countries.

Dr Shay McGuinness, MRINZ Senior Clinical Research Fellow says "In my view this is the most important recent study conducted in cardiac surgery. Quite simply it's a game-changer for patients who have a history of atrial fibrillation who need open heart surgery. At the time of their main surgery, they can have their left atrial appendix closed with no additional risk of bleeding or other complications. Our study showed that this dramatically reduced the risk of stroke for many years after the procedure."

2379 trial participants worldwide were randomly selected to have their left atrial appendage closed during cardiac surgery, while a control group of 2391 did not. Both were followed up for an average of almost 4 years, and it was found that stroke or other embolism occurred 33% less commonly in those in the occlusion group compared to the control group. There were no differences in the rates of bleeding during the operation, complications after, or death. This means the study showed that the occlusion procedure helped to prevent stroke in patients with AF and did not increase the rates of complications.

The finding opens a new approach for stroke prevention in atrial fibrillation and will undoubtedly be incorporated into local and international guidelines.

MRINZ’s established Cardiothoracic Research Programme IOACS Net (the Improving Outcomes After Cardiothoracic Surgery Network), has been exploring the care of patients undergoing cardiac surgery at public hospitals across New Zealand since 2015. MRINZ also has a long history of stroke research, with a particular focus on ethnic disparities in post-stroke outcomes, and self-rehabilitation.

Professor Richard Beasley, Director of MRINZ says, "the findings from this trial have the power to change clinical practice both in Aotearoa New Zealand and globally, due to the marked reduction in risk of stroke with this surgical procedure. The LAAOS III study highlights the impact that the dedicated work of our IOACS Net cardiac surgeons, anaesthetists, intensivists, clinical perfusionists and researchers can have both locally and internationally."

 

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