Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, May 8, 2025

Optimizing Health-Related Quality of Life Assessments for Stroke Survivors: A Validation Study of Psychometric Properties for the Vietnamese Version of Stroke Impact Scale 3.0

Assessments like this that don't lead to EXACT RECOVERY PROTOCOLS are COMPLETELY FUCKING USELESS FOR RECOVERY!


Optimizing Health-Related Quality of Life Assessments for Stroke Survivors: A Validation Study of Psychometric Properties for the Vietnamese Version of Stroke Impact Scale 3.0

Thao Thi Phuong NguyenThao Thi Phuong Nguyen1,2*Hai Bui HoangHai Bui Hoang3,4Huyen Thi Thanh VuHuyen Thi Thanh Vu5,6Seung Won LeeSeung Won Lee10,7,8,9*
  • 1Academy of Medical Sciences, Ho Chi Minh, Vietnam
  • 2Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam
  • 3Department of Emergency and Critical Care Medicine, Hanoi Medical University, Hanoi, Vietnam
  • 4Emergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi Medical University, Hanoi, Vietnam
  • 5Department of Geriatrics, Hanoi Medical University, Hanoi, Vietnam
  • 6Scientific Research Department, National Geriatric Hospital, Hanoi, Vietnam
  • 7Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea
  • 8Department of Artificial Intelligence, Sungkyunkwan University, Suwon, Republic of Korea
  • 9Department of Metabiohealth, Sungkyunkwan University, Suwon, Republic of Korea
  • 10Personalized Cancer Immunotherapy Research Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea

The final, formatted version of the article will be published soon.

    Background: 

    Ensuring lifelong health among aging populations necessitates comprehensive assessments of functional recovery and quality of life, particularly for vulnerable groups such as elderly stroke survivors. While the Stroke Impact Scale (SIS) 3.0 is a widely validated instrument for evaluating health-related quality of life (HRQoL) in stroke survivors, its psychometric properties have not yet been examined in the Vietnamese context. This study aimed to translate, culturally adapt, and validate the Vietnamese version of the SIS 3.0 (V-SIS 3.0), providing a robust tool to support holistic, multidimensional approaches to stroke rehabilitation in aging populations.

    Methods: 

    A cross-sectional study was conducted from July to December 2021 at the National Geriatric Hospital in Hanoi, Vietnam. The study enrolled 256 stroke survivors aged 45 years or older who had experienced a stroke between one month and one year prior to participation. The V-SIS 3.0 questionnaire was developed through a rigorous forward and backward translation process. Its factorial structure was examined using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Internal consistency was assessed via Cronbach’s alpha, and convergent and divergent validity were evaluated through correlation analyses. Additionally, Item Response Theory (IRT) was employed to examine item discrimination and difficulty.

    Results: 

    EFA identified a four-factor structure consisting of Physical (28 items), Cognitive (12 items), Social Participation (10 items), and Emotional (8 items) domains. CFA supported this structure, indicating a good model fit (RMSEA = 0.080, CFI = 0.925, TLI = 0.918, SRMR = 0.053). The instrument demonstrated excellent internal consistency across all domains, with Cronbach’s alpha values of 0.971 for Physical, 0.950 for Cognitive, 0.949 for Social Participation, and 0.920 for Emotional. Convergent and divergent validity were confirmed by strong item correlations within each factor, while IRT analysis further indicated high discrimination and appropriate difficulty levels for most items.

    Conclusions: 

    The V-SIS 3.0 is the first culturally adapted and validated tool to assess HRQoL in Vietnamese stroke survivors. By offering a reliable, multidimensional evaluation of physical, cognitive, emotional, and social well-being, this instrument enhances clinical assessments, informs targeted interventions, and ultimately contributes to more effective aging and lifestyle strategies for stroke survivors in Vietnam.

    Keywords: Stroke, health-related quality of life, Validation Studies as Topic, Psychometric, Vietnam

    Received: 07 Feb 2025; Accepted: 30 Apr 2025.

    Copyright: © 2025 Nguyen, Hoang, Vu and Lee. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Thao Thi Phuong Nguyen, Academy of Medical Sciences, Ho Chi Minh, Vietnam
    Seung Won Lee, Department of Precision Medicine, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea 

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